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科研机构
山东大学 [72]
上海药物研究所 [12]
复旦大学上海医学院 [7]
西安交通大学 [6]
北京大学 [5]
化学研究所 [3]
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期刊论文 [116]
会议论文 [2]
专著章节/文集论文 [1]
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2022 [1]
2020 [2]
2019 [3]
2018 [6]
2017 [5]
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organic co... [1]
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Deep Learning-Based Morphological Classification of Endoplasmic Reticulum Under Stress
期刊论文
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 9, 页码: 13
作者:
Guo, Yuanhao
;
Shen, Di
;
Zhou, Yanfeng
;
Yang, Yutong
;
Liang, Jinzhao
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/03/17
ER stress
morphological classification
image biomarker
deep learning
homeostasis
A removable directing group-assisted Rh(iii)-catalyzed direct C-H bond activation/annulation cascade to synthesize highly fused isoquinolines
期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2020, 卷号: 7, 期号: 20, 页码: 3186-3192
作者:
Cheng, Yilang
;
Han, Xu
;
Li, Junyou
;
Zhou, Yu
;
Liu, Hong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/12/24
Recent advances in AFM-based biological characterization and applications at multiple levels
期刊论文
SOFT MATTER, 2020, 卷号: 16, 期号: 39, 页码: 8962-8984
作者:
Liang WF(梁文峰)
;
Shi, Haohao
;
Yang XL(杨谢柳)
;
Wang, Junhai
;
Yang WG(杨文广)
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/10/31
ATOMIC-FORCE MICROSCOPY
MECHANICAL-PROPERTIES
CANCER-CELLS
TISSUE STIFFNESS
MICROMECHANICAL PROPERTIES
VISCOELASTIC PROPERTIES
SINGLE-MOLECULE
ADHESION
VISUALIZATION
MEMBRANE
A Knowledge Graph based Bidirectional Recurrent Neural Network Method for Literature-based Discovery
会议论文
Proceedings - 2018 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2018
作者:
Sang, S.
;
Yang, Z.
;
Liu, X.
;
Wang, L.
;
Zhang, Y.
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  |  
浏览/下载:14/0
  |  
提交时间:2019/12/02
Association reactions
Bioinformatics
Embeddings
Graphic methods
Recurrent neural networks
Vector spaces, Bidirectional recurrent neural networks
Biomedical abstracts
Drug discovery
Graph embeddings
Knowledge graphs
Learning methods
Literature-based discoveries
Short term memory, Deep learning
Novel discoveries targeting gemcitabine-based chemoresistance and new therapies in pancreatic cancer: How far are we from the destination?
期刊论文
2019
作者:
Luo Wenhao
;
Yang Gang
;
Qiu Jiangdong
;
Luan Jingyang
;
Zhang Ying
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  |  
浏览/下载:8/0
  |  
提交时间:2020/01/03
chemistry
drug therapy
metabolism
pancreatic cancer
prevention
Biological Activities of Artemisinin Derivatives Beyond Malaria
期刊论文
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 卷号: 19, 期号: 3, 页码: 205-222
作者:
Liu, Xiaoyan
;
Cao, Jianguo
;
Huang, Guozheng
;
Zhao, Qingjie
;
Shen, Jingshan
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  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
Anticancer activity
Antiviral activity
Artemisinin
Artemisinin derivatives
Dimer
Trimer
Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Huang, Wenjing
;
Tan, Wenfu
;
Zhang, Ao
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  |  
浏览/下载:28/0
  |  
提交时间:2019/01/08
Bcl-2
Bcl-xL
Sulfonamide
Navitoclax
Apoptosis
Cancer incidence and mortality patterns in Luwan district of Shanghai during 2002-2011
期刊论文
DRUG DISCOVERIES AND THERAPEUTICS, 2018, 卷号: 12, 期号: 2
作者:
Wang, Jue
;
Gao, Shuna
;
Wang, Yejing
;
Zhou, Jianjun
;
Lin, Jing
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  |  
浏览/下载:5/0
  |  
提交时间:2019/12/05
Cancer
incidence
mortality
temporal trend
Shanghai
Molecular mechanism and targeted therapy of Hsp90 involved in lung cancer: New discoveries and developments (Review)
期刊论文
INTERNATIONAL JOURNAL OF ONCOLOGY, 2018, 卷号: 52, 页码: 321-336
作者:
Rong, Biaoxue
;
Yang, Shuanying
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/11/26
expression
drug target
lung cancer
Hsp90
molecular targeted therapy
A thermo-/pH-responsive hydrogel (PNIPAM-PDMA-PAA) with diverse nanostructures and gel behaviors as a general drug carrier for drug release
期刊论文
POLYMER CHEMISTRY, 2018, 卷号: 9, 页码: 4063-4072
作者:
Chen, Yan[1]
;
Gao, Yuting[2]
;
da Silva, Lucilia P.[3]
;
Pirraco, Rogerio P.[4]
;
Ma, Mengdi[5]
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  |  
浏览/下载:8/0
  |  
提交时间:2019/04/22
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