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CORC

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Recent progress in HIV-1 inhibitors targeting the entrance channel of HIV-1 non-nucleoside reverse transcriptase inhibitor binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 174
作者:  Gu, Shuang-Xi;  Xiao, Ting;  Zhu, Yuan-Yuan;  Liu, Gen-Yan;  Chen, Fen-Er
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/05
Targeting the hydrophobic channel of NNIBP: discovery of novel 1,2,3-triazole-derived diarylpyrimidines as novel HIV-1 NNRTIs with high potency against wild-type and K103N mutant virus 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2019, 卷号: 17, 期号: 12, 页码: 3202-3217
作者:  Zhou, Zhongxia;  Liu, Tao;  Wu, Gaochan;  Kang, Dongwei;  Fu, Zhipeng
收藏  |  浏览/下载：11/0  |  提交时间：2019/12/11
Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145
作者:  Jin, KaiJun;  Yin, Hong;  De Clercq, Erik;  Pannecouque, Christophe;  Meng, Ge
收藏  |  浏览/下载：2/0  |  提交时间：2019/12/05
Discovery of novel diarylpyrimidines as potent HIV-1 NNRTIs by investigating the chemical space of a less explored "hydrophobic channel" 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2018, 卷号: 16, 期号: 6, 页码: 1014-1028
作者:  Zhou, Zhongxia;  Liu, Tao;  Kang, Dongwei;  Huo, Zhipeng;  Wu, Gaochan
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Structural modifications of diarylpyrimidines (DAPYs) as HIV-1 NNRTIs: Synthesis, anti-HIV activities and SAR 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 8, 页码: 2491-2497
作者:  Lu, Huan-Huan;  Xue, Ping;  Zhu, Yuan-Yuan;  Ju, Xiu-Lian;  Zheng, Xiao-Jiao
收藏  |  浏览/下载：15/0  |  提交时间：2019/09/25
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 352-363
作者:  Chen, Wenmin;  Zhan, Peng;  Daelemans, Dirk;  Yang, Jiapei;  Huang, Boshi
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16
Novel diarylpyrimidines and diaryltriazines as potent HIV-1 NNRTIs with dramatically improved solubility: a patent evaluation of US20140378443A1 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2016, 卷号: 26, 期号: 2, 页码: 281-289
作者:  Huang, Boshi;  Kang, Dongwei;  Yang, Jiapei;  Zhan, Peng;  Liu, Xinyong
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16
Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2015, 卷号: 25, 期号: 12, 页码: 1477-1486
作者:  Meng, Qing;  Liu, Na;  Huang, Boshi;  Zhan, Peng;  Liu, Xinyong
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17
Structural modification of diarylpyrimidine derivatives as HIV-1 reverse transcriptase inhibitors 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2015, 卷号: 24, 期号: 1
作者:  Gu, Shuang-Xi;  Zhu, Yuan-Yuan;  Chen, Fen-Er;  De Clercq, Erik;  Balzarini, Jan
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/19
Design and synthesis of a new series of cyclopropylamino-linking diarylpyrimidines as HIV non-nucleoside reverse transcriptase inhibitors 期刊论文
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2014, 卷号: 62, 期号: [db:dc_citation_issue], 页码: 334-341
作者:  Liu, Yang;  Meng, Ge;  Zheng, Aqun;  Chen, Fener;  Chen, Wenxue
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/03

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