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上海药物研究所 [3]
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期刊论文 [13]
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DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:
Wan, Fangping
;
Zhu, Yue
;
Hu, Hailin
;
Dai, Antao
;
Cai, Xiaoqing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Deep learning
Machine learning
Drug discovery
In silico drug screening
Compound-protein interaction prediction
Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2016, 卷号: 9
作者:
Xu, Hang
;
Zhang, Yu
;
Zhang, Fan
;
Yuan, San-na
;
Shao, Feng
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2016/11/14
social stress
adolescent
cognitive flexibility
medial prefrontal cortex (mPFC)
brain-derived neurotrophic factor (BDNF)
Practical method for the definition of chromatographic peak parameters in preparative liquid chromatography
期刊论文
JOURNAL OF SEPARATION SCIENCE, 2016, 卷号: 39, 期号: 20, 页码: 3917-3926
作者:
Shen, Aijin
;
Jin, Gaowa
;
Guo, Zhimou
;
Xiao, Yuansheng
;
Yan, Jingyu
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2017/10/29
Basic compounds
Chromatographic parameters
Concentration distribution
Peak broadening
Preparative liquid chromatography
Polydopamine-based surface modification of mesoporous silica nanoparticles as pH-sensitive drug delivery vehicles for cancer therapy
期刊论文
JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2016, 卷号: 463
作者:
Chang, Danfeng
;
Gao, Yongfeng
;
Wang, Lijun
;
Liu, Gan
;
Chen, Yuhan
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/05
Mesoporous silica nanoparticles
pH-sensitive
Desipramine
Polydopamine
Cancer nanotechnology
Effects of Duloxetine Treatment on Cognitive Flexibility and BDNF Expression in the mPFC of Adult Male Mice Exposed to Social Stress during Adolescence
期刊论文
FRONTIERS IN MOLECULAR NEUROSCIENCE, 2016
Xu, Hang
;
Zhang, Yu
;
Zhang, Fan
;
Yuan, San-na
;
Shao, Feng
;
Wang, Weiwen
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2017/12/03
social stress
adolescent
cognitive flexibility
medial prefrontal cortex (mPFC)
brain-derived neurotrophic factor (BDNF)
NEUROTROPHIC FACTOR EXPRESSION
MEDIAL PREFRONTAL CORTEX
MATERNAL SEPARATION
MAJOR DEPRESSION
DESIPRAMINE TREATMENT
CEREBRAL-CORTEX
BRAIN
RATS
MEMORY
IMPAIRMENT
Effects of aspirin on immobile behavior and endocrine and immune changes in the forced swimming test: Comparison to fluoxetine and imipramine
期刊论文
pharmacology biochemistry and behavior, 2014
Guan, Xi-ting
;
Shao, Feng
;
Xie, Xi
;
Chen, Lin
;
Wang, Weiwen
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2015/11/11
Aspirin
Antidepressant
Forced swimming test
Corticosterone
IL-6
TNF-alpha
NECROSIS-FACTOR-ALPHA
STRESS-INDUCED INCREASE
MAJOR DEPRESSION
ACETYLSALICYLIC-ACID
ANTIDEPRESSANT TREATMENTS
INFLAMMATORY MARKERS
ANTIINFLAMMATORY DRUGS
DESIPRAMINE TREATMENT
REUPTAKE INHIBITORS
MONOAMINE REUPTAKE
In Vivo Fast Equilibrium Microextraction by Stable and Biocompatible Nanofiber Membrane Sandwiched in Microfluidic Device
期刊论文
analytical chemistry, 2013, 卷号: 85, 期号: 23, 页码: 11524-11531
作者:
Wu, Qian
;
Wu, Dapeng
;
Guan, Yafeng
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2014/09/11
Desipramine Pretreatment Improves Sympathetic Remodeling and Ventricular Fibrillation Threshold after Myocardial Ischemia
期刊论文
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY, 2012
作者:
Wu, Xiaolin
;
Jiang, Hong
;
Yu, Lilei
;
Hu, Xiaorong
;
Liu, Wenwei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/05
Sequence polymorphisms of MC1R gene and their association with depression and antidepressant response
期刊论文
PSYCHIATRIC GENETICS, 2011, 卷号: 21, 期号: 1, 页码: 14-18
作者:
Wu, Gui-Sheng
;
Luo, Huai-Rong
;
Dong, Chuanhui
;
Mastronardi, Claudio
;
Licinio, Julio
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2012/07/25
antidepressant
association
haplotype
major depression
melanocortin 1 receptor
single nucleotide polymorphisms
Increased dopaminergic signaling impairs aversive olfactory memory retention in Drosophila
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2008, 卷号: 370, 期号: 1, 页码: 82-86
Zhang, Shixing
;
Yin, Yan
;
Lu, Huimin
;
Guo, Aike
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2012/07/23
drosophila
dopamine
olfactory memory
NEURONS
MELANOGASTER
TRANSPORTER
ACTIVATION
EXPRESSION
COCAINE
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