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CORC

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Discovery of potent HIV-1 non-nucleoside reverse transcriptase inhibitors by exploring the structure-activity relationship of solvent-exposed regions I 期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 93, 期号: 4, 页码: 430-437
作者:  Kang, Dongwei;  Wang, Zhao;  Chen, Meng;  Feng, Da;  Wu, Gaochan
收藏  |  浏览/下载：9/0  |  提交时间：2019/12/11
Further Exploring Solvent-Exposed Tolerant Regions of Allosteric Binding Pocket for Novel HIV-1 NNRTIs Discovery 期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 4, 页码: 370-375
作者:  Kang, Dongwei;  Wang, Zhao;  Zhang, Heng;  Wu, Gaochan;  Zhao, Tong
收藏  |  浏览/下载：8/0  |  提交时间：2019/12/11
The discovery of novel diarylpyri(mi) dine derivatives with high level activity against a wide variety of HIV-1 strains as well as against HIV-2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2051-2060
作者:  Lu, Xueyi;  Yang, Jiapei;  Kang, Dongwei;  Gao, Ping;  Daelemans, Dirk
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11
Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 16, 页码: 4397-4406
作者:  Huang, Boshi;  Wang, Xueshun;  Liu, Xinhao;  Chen, Zihui;  Li, Wanzhuo
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 352-363
作者:  Chen, Wenmin;  Zhan, Peng;  Daelemans, Dirk;  Yang, Jiapei;  Huang, Boshi
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16
Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 109, 页码: 294-304
作者:  Yang, Jiapei;  Chen, Wenmin;  Kang, Dongwei;  Lu, Xueyi;  Li, Xiao
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17
Design, synthesis and evaluation of novel HIV-1 NNRTIs with dual structural conformations targeting the entrance channel of the NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 115, 页码: 53-62
作者:  Meng, Qing;  Chen, Xuwang;  Kang, Dongwei;  Huang, Boshi;  Li, Wenxin
收藏  |  浏览/下载：10/0  |  提交时间：2019/12/17
基于靶点结构的新型DAPY类HIV-1 NNRTIs的设计、合成及活性研究 会议论文
中国化学会第30届学术年会-第二十八分会：化学生物学
作者:  李潇;  展鹏;  刘新泳
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/31
HIV-1  NNRTIs  DAPY  
Novel fluorine-containing DAPY derivatives as potent HIV-1 NNRTIs: a patent evaluation of WO2014072419 期刊论文
EXPERT OPINION ON THERAPEUTIC PATENTS, 2015, 卷号: 25, 期号: 12, 页码: 1477-1486
作者:  Meng, Qing;  Liu, Na;  Huang, Boshi;  Zhan, Peng;  Liu, Xinyong
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17
Synthesis and biological evaluation of DAPY-DPEs hybrids as non-nucleoside inhibitors of HIV-1 reverse transcriptase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2015, 卷号: 23, 期号: 3
作者:  Wu, Hai-Qiu;  Yao, Jin;  He, Qiu-Qin;  Chen, Wen-Xue;  Chen, Fen-Er
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/19

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