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Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Meng, Jian
;
Zhang, Hua
;
Bao, Jing-jing
;
Chen, Zhen-dong
;
Liu, Xiao-yun
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2021/06/11
metabolism
mass balance
distribution
covalent binding
furmonertinib
Systematic analysis of the metabolites of Angelicae Pubescentis Radix by UPLC-Q-TOF-MS combined with metabonomics approaches after oral administration to rats
期刊论文
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2020, 卷号: 188
作者:
Wan, Mei-Qi
;
Liu, Xiao-Yan
;
Gao, Hua
;
Wang, Tian-Xia
;
Yang, Yan-Fang
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2022/03/01
Angelicae Pubescentis radix
Metabolites
UPLC-Q-TOF-MS
Metabonomics
Sex-dependent aberrant PFC development in the adolescent offspring rats exposed to variable prenatal stress
期刊论文
INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE, 2020, 页码: 13
作者:
Niu, Yunxia
;
Wang, Tao
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  |  
浏览/下载:65/0
  |  
提交时间:2020/09/28
adolescence
physiological index
prefrontal cortex
prepulse inhibition
repeated variable prenatal stress
Species differences in the CYP3A-catalyzed metabolism of TPN729, a novel PDE5 inhibitor
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 9
作者:
Tian, Qian-qian
;
Zhu, Yun-ting
;
Diao, Xing-xing
;
Zhang, Xiang-lei
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/12/24
PDE5 inhibitor
TPN729
M3
species difference
pharmacokinetics
metabolite identification
Fructo-oligosaccharides from Morinda officinalis remodeled gut microbiota and alleviated depression features in a stress rat model
期刊论文
PHYTOMEDICINE, 2020, 卷号: 67, 页码: 12
作者:
Chi, Liandi
;
Khan, Imran
;
Lin, Zibei
;
Zhang, Jiwen
;
Lee, M. Y. Simon
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Inulin-type fructo-oligosaccharides (FOSs)
Chronic unpredictable mild stress (CUMS)
Behavioral tests
Gut microbiota
Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis
期刊论文
LIPIDS IN HEALTH AND DISEASE, 2019, 卷号: 18, 期号: 1, 页码: 11
作者:
Yang, Rui-Xu
;
Pan, Qin
;
Liu, Xiao-Lin
;
Zhou, Da
;
Xin, Feng-Zhi
收藏
  |  
浏览/下载:143/0
  |  
提交时间:2019/12/02
Ceramides
Autophagy
High fat diet
Non-alcoholic fatty liver disease
Distinct gene alterations between Fos-expressing striatal and thalamic neurons after withdrawal from methamphetamine self-administration
期刊论文
BRAIN AND BEHAVIOR, 2019, 页码: 12
作者:
Li, Xuan
;
Davis, Ian R.
;
Lofaro, Olivia M.
;
Zhang, Jianjun
;
Cimbro, Raffaello
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/10/25
anterior intralaminar nucleus of thalamus
dorsal striatum
fluorescence-activated cell sorting
Fos
incubation of drug craving
methamphetamine relapse
Dissecting the Metabolic Phenotype of the Antihypertensive Effects of Five Uncaria Species on Spontaneously Hypertensive Rats
期刊论文
FRONTIERS IN PHARMACOLOGY, 2019, 卷号: 10, 页码: 11
作者:
Feng, Zijin
;
Hou, Jinjun
;
Yu, Yang
;
Wu, Wenyong
;
Deng, Yanping
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/07/01
Uncaria Stem with Hooks
multiple botanical origins
spontaneously hypertensive rats
systolic blood pressure
metabonomics
indole alkaloids
NMR Based Metabolomics Comparison of Different Blood Sampling Techniques in Awake and Anesthetized Rats
期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 14, 页码: 16
作者:
Du, Hongying
;
Li, Shuang
;
Zhang, Yingfeng
;
Guo, Huiling
;
Wu, Liang
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2019/12/06
blood collection
serum
NMR
metabolomics
saphenous vein
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