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北京大学 [2]
大连化学物理研究所 [2]
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湖南大学 [1]
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期刊论文 [9]
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2018 [2]
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2010 [1]
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Chemoprobe-based assays of histone lysine demethylase 1A target occupation enable in vivo pharmacokinetics and -dynamics studies of KDM1A inhibitors.
期刊论文
The Journal of biological chemistry, 2019
作者:
Cristina Mascaró
;
Alberto Ortega
;
Elena Carceller
;
Raquel Ruiz Rodriguez
;
Filippo Ciceri
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/12/17
chemoprobe
chemoproteomics
drug development
enzyme inactivation
epigenetics
lysine demethylase
pharmacokinetics
protein drug interaction
Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 卷号: 115, 期号: 26, 页码: E5896-E5905
作者:
Dai, Jianye
;
Liang, Kai
;
Zhao, Shan
;
Jia, Wentong
;
Liu, Yuan
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/04/09
Baicalin
Cpt1
Obesity
Chemical Proteomics
Steatosis
Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
期刊论文
Proc Natl Acad Sci U S A., 2018, 页码: 1-10
作者:
Jianye Dai
;
Kai Liang
;
Shan Zhao
;
Wentong Jia
;
Yuan Liu
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2019/10/14
Quantitative time-resolved chemoproteomics reveals that stable O-GlcNAc regulates box C/D snoRNP biogenesis
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2017
Qin, Wei
;
Lv, Pinou
;
Fan, Xinqi
;
Quan, Baiyi
;
Zhu, Yuntao
;
Qin, Ke
;
Chen, Ying
;
Wang, Chu
;
Chen, Xing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
O-GlcNAcylation
metabolic labeling
proteomics
protein stability
snoRNP
MODIFIED PROTEINS
MASS-SPECTROMETRY
RIBOSOMAL-RNA
TRANSLATIONAL CONTROL
BIOSYNTHETIC-PATHWAY
CIRCADIAN CLOCK
CHRONIC DISEASE
H/ACA SNORNPS
BREAST-CANCER
CROSS-TALK
Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe
期刊论文
REDOX BIOLOGY, 2017
Chen, Ying
;
Cong, Yan
;
Quan, Baiyi
;
Lan, Tong
;
Chu, Xiaoyu
;
Ye, Zi
;
Hou, Xiaomeng
;
Wang, Chu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2017/12/03
Lipid-derived electrophile
4-hydroxy-2-nonenal
Chemoproteomics
Aminooxy probe
Activity-based protein profiling
QUANTITATIVE PROTEOMICS
PROTEIN CARBONYLATION
MASS-SPECTROMETRY
ABASIC SITES
DISEASE
IDENTIFICATION
PEROXIDATION
BIOTIN
ALKYLATION
CHEMISTRY
Multiplexed Thiol Reactivity Profiling for Target Discovery of Electrophilic Natural Products
期刊论文
2017, 卷号: 24, 期号: 11, 页码: 1416-+
作者:
Tian, Caiping
;
Sun, Rui
;
Liu, Keke
;
Fu, Ling
;
Liu, Xiaoyu
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
chemoproteomics
cysteine
electrophile
gambogic acid
iTRAQ
lactone
mass spectrometry
natural products
Preparation and characterization of vorinostat-coated beads for profiling of novel target proteins
期刊论文
journal of chromatography a, 2014, 卷号: 1372, 页码: 34-41
作者:
Lu, Congcong
;
Zhang, Kai
;
Zhang, Yi
;
Tan, Minjia
;
Li, Yijun
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2015/11/17
Proteomics
HPLC-MS/MS
Chemical probe
Target proteins
Vorinostat
Preparation and characterization of vorinostat-coated beads for profiling of novel target proteins
期刊论文
JOURNAL OF CHROMATOGRAPHY A, 2014, 卷号: 1372, 页码: 34-41
作者:
Lu, Congcong
;
Zhang, Kai
;
Zhang, Yi
;
Tan, Minjia
;
Li, Yijun
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Proteomics
HPLC-MS/MS
Chemical probe
Target proteins
Vorinostat
Combined Comparative and Chemical Proteomics on the Mechanisms of levo-Tetrahydropalmatine-Induced Antinociception in the Formalin Test
期刊论文
journal of proteome research, 2010, 卷号: 9, 期号: 6, 页码: 3225-3234
作者:
Wang, Chen
;
Zhou, Jiangrui
;
Wang, Shuowen
;
Ye, Mingliang
;
Jiang, Chunlei
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2010/11/30
2-D nano LC
proteomics
chemoproteomics
tetrahydropalmatine
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