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科研机构
上海药物研究所 [4]
中南大学 [4]
昆明医科大学 [3]
复旦大学上海医学院 [2]
南华大学 [1]
北京大学 [1]
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期刊论文 [18]
学位论文 [1]
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2021 [1]
2019 [1]
2018 [2]
2017 [1]
2016 [1]
2015 [2]
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Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity
期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:
Qiao, Shida
;
Feng, Sisi
;
Wu, Zhitao
;
He, Ting
;
Ma, Chen
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/05/24
CYP2B6 genetic polymorphisms influence chronic obstructive pulmonary disease susceptibility in the Hainan population
期刊论文
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE, 2019, 卷号: 14, 页码: 2103-2115
作者:
Ding, Yipeng*
;
Li, Quanni
;
Feng, Qiong
;
Xu, Dongchuan
;
Wu, Cibing
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
*COPD
*CYP2B6
*case-control study
*chronic obstructive pulmonary disease
*gene polymorphisms
Direct and quantitative evaluation of the major human CYP contribution (fmCYP) to drug clearance using the in vitro Silensomes™ model
期刊论文
Xenobiotica; the fate of foreign compounds in biological systems, 2018, 页码: 1-14
作者:
Parmentier, Yannick
;
Pothier, Corinne
;
Hewitt, Nicola
;
Vincent, Ludwig
;
Caradec, Fabrice
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  |  
浏览/下载:17/0
  |  
提交时间:2019/01/08
CYP2B6*6基因多态性对中国健康受试者单次注射丙泊酚的药代动力学和药效学影响 Effect of genetic polymorphism of CYP2B6*6 on pharmacokinetics and pharmacodynamics of single dose propofol in Chinese healthy subjects
期刊论文
2018, 卷号: 34, 期号: 9, 页码: 1052
作者:
古安城[1,4]
;
曹婉雯[1]
;
张建萍[4]
;
秦再生[2]
;
陈滨[3]
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/13
细胞色素P2B6*6
丙泊酚
药代动力学
药效学
Metabolic profiling of five flavonoids from Dragon's Blood in human liver microsomes using high-performance liquid chromatography coupled with high resolution mass spectrometry
期刊论文
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2017, 卷号: 1052, 页码: 91-102
作者:
Li, Yujuan
;
Zhang, Yushi
;
Wang, Rui
;
Wei, Lizhong
;
Deng, Yulin
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2018/04/10
Dragon's Blood
Human Liver Microsomes
Hplc-hr-ms
Metabolites
Genetic markers in CYP2C19 and CYP2B6 for prediction of cyclophosphamide's 4-hydroxylation, efficacy and side effects in Chinese patients with systemic lupus erythematosus
期刊论文
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2016, 卷号: 81, 页码: 327-340
作者:
Shu, Wenying[1,2]
;
Guan, Su[3]
;
Yang, Xiuyan[4]
;
Liang, Liuqin[4]
;
Li, Jiali[1]
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/04/24
cyclophosphamide
CYP2B6
CYP2C19
lupus
pharmacogenetics
Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
期刊论文
DRUG METABOLISM AND DISPOSITION, 2015, 卷号: 43, 期号: 10, 页码: 1632-1641
作者:
Liu, Cai
;
Chen, Zhaoqiang
;
Zhong, Kan
;
Li, Liang
;
Zhu, Weiliang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
Effect of CYP2B6 Gene Polymorphisms on Efavirenz Plasma Concentrations in Chinese Patients with HIV Infection
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 6
作者:
Meng, Xianmin
;
Yin, Kang
;
Wang, Jiangrong
;
Dong, Ping
;
Liu, Li
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
Human Hepatocytes with Drug Metabolic Function Induced from Fibroblasts by Lineage Reprogramming
期刊论文
cell stem cell, 2014
Du, Yuanyuan
;
Wang, Jinlin
;
Jia, Jun
;
Song, Nan
;
Xiang, Chengang
;
Xu, Jun
;
Hou, Zhiyuan
;
Su, Xiaohua
;
Liu, Bei
;
Jiang, Tao
;
Zhao, Dongxin
;
Sun, Yingli
;
Shu, Jian
;
Guo, Qingliang
;
Yin, Ming
;
Sun, Da
;
Lu, Shichun
;
Shi, Yan
;
Deng, Hongkui
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2015/11/11
CELL-DERIVED HEPATOCYTES
PANCREAS PROGENITORS
LIVER
DIFFERENTIATION
MATURATION
SYSTEMS
Genetic Variants of Pregnane X Receptor (PXR) and CYP2B6 Affect the Induction of Bupropion Hydroxylation by Sodium Ferulate
期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 6, 页码: e62489
作者:
Gao, Lichen
;
He, Yijing
;
Tang, Jie
;
Yin, Jiye
;
Huang, Zhengyu
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Haplotypes,Drug metabolism,Hydroxylation,Drug-drug interactions,Pharmacokinetics,Variant genotypes,Gene expression,Genetic polymorphism
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