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科研机构
上海药物研究所 [4]
大连化学物理研究所 [3]
金属研究所 [1]
湖南农业大学 [1]
内容类型
期刊论文 [8]
会议论文 [1]
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2011 [1]
2007 [1]
2006 [2]
2004 [1]
2003 [3]
2001 [1]
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物理化学 [1]
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In vitro biotransformation and investigation of metabolic enzymes possibly responsible for the metabolism of bisdesoxyolaquindox in the liver fractions of rats, chicken, and pigs
期刊论文
Toxicology, 2011, 卷号: 279, 期号: 1-3, 页码: 155-166
作者:
Liu, Zhao-Ying
;
Chen, Dong-Mei
;
Huang, Ling-Li
;
Tao, Yan-Fei
;
Yao, Min
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/23
ADH
alcohol dehydrogenase
ALDH
aldehyde dehydrogenase
ANF
α-naphthoflavon
AO
aldehyde oxidase
BDES
bisdesoxyolaquindox
CID
collision-induced dissociation
Clint
intrinsic clearance
CPZ
chlorpromazine
CYP
cytochrome P450
DDTC
diethyldithiocarbamate
DIS
disulfiram
HCO
7-hydroxycoumarin
IT
ion trap
LC/MS-IT-TOF
high-performance liquid chromatography combined with hybrid ion trap/time-of-flight mass spectrometry
MEN
menadione
MOP
8-methoxypsoralen
MP
4-methylpyrazole
MQCA
3-methylquinoxaline 2-carboxylic acid
QUI
quinidine
SUL
sulphaphenazole
TAO
troleandomycin
TOF
time-of-flight
XO
xanthine oxidase
Bisdesoxyolaquindox
Metabolic enzymes
Metabolism
Olaquindox
Microsomes
CYP isoenzymes
Precolumn derivatization of cysteine residues for quantitative analysis of five major cytochrome P450 isoenzymes by liquid chromatography/tandem mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2007, 卷号: 21, 期号: 20, 页码: 3234-3244
作者:
Duan, Xiaotao
;
Chen, Xiaoyan
;
Yang, Yiming
;
Zhong, Dafang
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Characterization of hepatic drug-metabolizing activities of Bama miniature pigs (Sus scrofa domestica): Comparison with human enzyme analogs
期刊论文
comparative medicine, 2006, 卷号: 56, 期号: 4, 页码: 286-290
作者:
Li, Jian
;
Liu, Yong
;
Zhang, Jiang-Wei
;
Wei, Hong
;
Yang, Ling
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2015/11/11
Role of rat liver cytochrome P450 3A and 2D in metabolism of imrecoxib
期刊论文
ACTA PHARMACOLOGICA SINICA, 2006, 卷号: 27, 期号: 3, 页码: 372-380
作者:
Xu HY
;
Xie ZY
;
Zhang P
;
Sun J
;
Chu FM
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2021/02/02
NONSTEROIDAL ANTIINFLAMMATORY DRUGS
COX-2 INHIBITORS
IN-VITRO
MICROSOMES
CYCLOOXYGENASE-2
OSTEOARTHRITIS
ISOENZYMES
NSAIDS
VIVO
imrecoxib
cytochrome P450
metabolism
liver microsomes
Structural determinants of steroids for cytochrome P450 3A4-mediated metabolism
期刊论文
journal of molecular structure-theochem, 2004, 卷号: 710, 期号: 1-3, 页码: 215-221
作者:
Wang, YH
;
Han, KL
;
Yang, SL
;
Yang, L
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  |  
浏览/下载:41/0
  |  
提交时间:2010/11/30
CYP3A4
steroids
pharmacophore modeling
E-state map
Effects of huperzine A on liver cytochrome P-450 in rats
期刊论文
ACTA PHARMACOLOGICA SINICA, 2003, 卷号: 24, 期号: 8, 页码: 831-835
作者:
Ma, XC
;
Wang, HX
;
Xin, J
;
Zhang, T
;
Tu, ZH
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/01/08
huperzine A
cytochrome P-450
cytochrome P-450CYP1A2
liver
rat
Identification of cytochrome P450 1A2 as enzyme involved in the microsomal metabolism of Huperzine A
期刊论文
EUROPEAN JOURNAL OF PHARMACOLOGY, 2003, 卷号: 461, 期号: 2-3, 页码: 89-92
作者:
Ma, XC
;
Wang, HX
;
Xin, H
;
Zhang, T
;
Tu, ZH
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/01/08
Huperzine A
metabolism
cytochrome p450
microsome
effectsofhuperzineaonlivercytochromep450inrats
期刊论文
actapharmacologicasinica, 2003, 卷号: 24, 期号: 8, 页码: 831
作者:
Ma Xiaochao
;
Wang Haixue
;
Xin Jian
;
Zhang Ting
;
Tu Zenghong
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/07/01
ALZHEIMERS-DISEASE
OXIDATION
ENZYMES
MICROSOMES
CHEMICALS
TACRINE
huperzine A
cytochrome P-450
cytochrome P-450CYP1A2
liver
rat
Screening Study of the Inhibitory Effects 17 Steroids on 6 Major Cytochrome P450 Isoenzymes
会议论文
the 1st asia pacific issx meeting, 韩国, 2001-5-24
张江伟
;
刘勇
;
李巍
;
杨凌
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  |  
浏览/下载:13/0
  |  
提交时间:2011/07/11
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