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科研机构
上海药物研究所 [12]
昆明植物研究所 [6]
厦门大学 [5]
中国科学院大学 [3]
北京大学 [2]
高能物理研究所 [2]
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期刊论文 [41]
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Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Efficient synthesis, biological evaluation, and docking study of isatin based derivatives as caspase inhibitors
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2020, 卷号: 35, 期号: 1, 页码: 1674-1684
作者:
Firoozpour, Loghman
;
Gao, Lixin
;
Moghimi, Setareh
;
Pasalar, Parvin
;
Davoodi, Jamshid
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/12/24
Caspase inhibitor
Isatin sulphonamides
docking studies
Pharmacophore
apoptosis
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:
Lai Mengzhen
;
Song Peiran
;
Dou Dou
;
Diao Yanyan
;
Tong Linjiang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton’s tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
MiR-155 affects osteosarcoma cell proliferation and invasion through regulating NF-kappa B signaling pathway
期刊论文
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2018, 卷号: 22, 期号: 22, 页码: 7633-7639
作者:
Lu, S.
;
Liao, Q-S
;
Tang, L.
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2019/01/22
Mir-155
Nf-kappa b
Osteosarcoma
Proliferation
Invasion
Vitamin E deficiency depressed gill immune response and physical barrier referring to NF-kB, TOR, Nrf2 and MLCK signalling in grass carp (Ctenopharyngodon idella) under infection of Flavobacterium columnare
期刊论文
AQUACULTURE, 2018, 卷号: 484, 期号: 1, 页码: 13-27
作者:
Pan, Jia-Hong
;
Feng, Lin
;
Jiang, Wei-Dan
;
Wu, Pei
;
Kuang, Sheng-Yao
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2019/07/03
Vitamin E
Grass carp (Ctenopharyngodon idella)
Immunity
Antioxidant capacity
Apoptosis
Tight junction
Gill
Synthesis and inhibitory effect of 10-chlorocanthin-6-one on ovarian cancer HO8910PM cells
期刊论文
BIOTECHNOLOGY LETTERS, 2018, 卷号: 40, 期号: 1, 页码: 23-30
作者:
Li, Wenhua
;
Chen, Yuwen
;
Sheng, Yuwen
;
Xie, Zeyu
;
Tang, Yaxiong
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/12/24
Bim
Cell apoptosis
10-Chlorocanthin-6-one
Cytotoxicity
Ovarian cancer cell line
Discovery of Novel Bromophenol Hybrids as Potential Anticancer Agents through the Ros-Mediated Apoptotic Pathway: Design, Synthesis and Biological Evaluation
期刊论文
MARINE DRUGS, 2017, 卷号: 15, 期号: 11, 页码: 18
作者:
Wang, Li-Jun
;
Guo, Chuan-Long
;
Li, Xiang-Qian
;
Wang, Shuai-Yu
;
Jiang, Bo
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2019/07/15
bromophenol hybrids
anticancer
structure-activity relationships
ROS
apoptotic pathway
Isoliquiritigenin suppresses IL-1 beta induced apoptosis and inflammation in chondrocyte-like ATDC5 cells by inhibiting NF-kappa B and exerts chondroprotective effects on a mouse model of anterior cruciate ligament transection
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2017, 卷号: 40, 期号: 6, 页码: 1709-1718
作者:
Ji, BC (Ji, Baochao)
;
Guo, WT (Guo, Wentao)
;
Ma, HR (Ma, Hairong)
;
Xu, BY (Xu, Boyong)
;
Mu, WB (Mu, Wenbo)
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2018/01/08
Isoliquiritigenin
Osteoarthritis
Chondrocytes
Anti-apoptosis
Anti-catabolic
Mor-platin a new platinum complex that can induce apoptosis and inhibit migration
期刊论文
Chinese Science Bulletin科学通报, 2017, 卷号: 62, 期号: 4, 页码: 270-278
作者:
Li, Jingling
;
Cao, Jianping
;
Chen, Chunying
;
Guo, Zhengqing
;
Zhang, Leshuai
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/08/27
Mor-platin a new platinum complex that can induce apoptosis and inhibit migration
期刊论文
Chinese Science Bulletin科学通报, 2017, 卷号: 62, 期号: 4, 页码: 270-278
作者:
Li, Jingling
;
Chen CY(陈春英)
;
Cao, Jianping
;
Zhang, Leshuai
;
Guo, Zhengqing
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/08/29
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