CORC

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CORC

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Repressing MYC by targeting BET synergizes with selective inhibition of PI3K alpha against B cell lymphoma 期刊论文
CANCER LETTERS, 2022, 卷号: 524, 页码: 206-218
作者:  Chen, Zi-qi;  Cao, Zhe-rui;  Wang, Yi;  Zhang, Xi;  Xu, Lan
收藏  |  浏览/下载：53/0  |  提交时间：2021/12/16
CYH33  MYC  P300  BET  B cell lymphoma  PI3K  
Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 19, 页码: 14822-14847
作者:  Wei, Dan;  Wang, Hanlin;  Zeng, Qinghe;  Wang, Wenjing;  Hao, Bingbing
收藏  |  浏览/下载：30/0  |  提交时间：2021/12/16
Multi-omics characterization of WNT pathway reactivation to ameliorate BET inhibitor resistance in liver cancer cells 期刊论文
GENOMICS, 2021, 卷号: 113, 期号: 3, 页码: 1057-1069
作者:  Liu, Yuwei;  Xue, Mengzhu;  Cao, Danyan;  Qin, Lihuai;  Wang, Ying
收藏  |  浏览/下载：33/0  |  提交时间：2021/08/17
Novel bivalent BET inhibitor N2817 exhibits potent anticancer activity and inhibits TAF1 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2021, 卷号: 185, 页码: 14
作者:  Wu, Qian;  Chen, Dan-Qi;  Sun, Lin;  Huan, Xia-Juan;  Bao, Xu-Bin
收藏  |  浏览/下载：116/0  |  提交时间：2021/05/24
Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian
收藏  |  浏览/下载：30/0  |  提交时间：2021/05/24
Discovery of selective HDAC/BRD4 dual inhibitors as epigenetic probes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 209, 页码: 20
作者:  Chen, Jingjing;  Li, Yalei;  Zhang, Jie;  Zhang, Minmin;  Wei, Aihuan
收藏  |  浏览/下载：26/0  |  提交时间：2021/05/24
The MYC Paralog-PARP1 Axis as a Potential TherapeuticTarget in MYC Paralog-Activated Small Cell Lung Cancer 期刊论文
FRONTIERS IN ONCOLOGY, 2020, 卷号: 10
作者:  Bian, Xing;  Wang, Xiaolin;  Zhang, Qiuyan;  Ma, Liying;  Cao, Guozhen
收藏  |  浏览/下载：57/0  |  提交时间：2020/11/30
Rational Design and Evaluation of 6-(Pyrimidin-2-ylamino)-3,4-dihydroquinoxalin-2(1H)-ones as Polypharmacological Inhibitors of BET and Kinases 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 17, 页码: 9787-9802
作者:  Lv, Kaikai;  Chen, Weicong;  Chen, Danqi;  Mou, Jie;  Zhang, Huijie
收藏  |  浏览/下载：12/0  |  提交时间：2020/12/21
A new BET inhibitor, 171, inhibits tumor growth through cell proliferation inhibition more than apoptosis induction 期刊论文
INVESTIGATIONAL NEW DRUGS, 2020, 卷号: 38, 期号: 3, 页码: 700-713
作者:  Damaneh, Mohammadali Soleimani;  Hu, Jian-Ping;  Huan, Xia-Juan;  Song, Shan-Shan;  Tian, Chang-Qing
收藏  |  浏览/下载：37/0  |  提交时间：2020/07/01
Discovery of 8-Methyl-pyrrolo[1,2-a]pyrazin-1(2H)-one Derivatives as Highly Potent and Selective Bromodomain and Extra-Terminal (BET) Bromodomain Inhibitors 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 3956-3975
作者:  Li, Zizhou;  Xiao, Senhao;  Yang, Yaxi;  Chen, Chao;  Lu, Tian
收藏  |  浏览/下载：28/0  |  提交时间：2020/07/01

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