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吉林大学白求恩第一... [18]
上海药物研究所 [12]
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期刊论文 [57]
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Characterization of the metabolites of tirabrutinib generated from rat, dog and human liver microsomes using ultra-high-performance liquid chromatography combined with high-resolution mass spectrometry
期刊论文
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2022, 卷号: 36
作者:
Zhang, Hongjian
;
Hu, Zhen
;
Zhang, Huiping
;
Sun, Xiyan
;
Yang, Jianming
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/03/28
Identification of Novel Fused Heteroaromatics-Based MALT1 Inhibitors by High-Throughput Screening to Treat B Cell Lymphoma
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 13, 页码: 9217-9237
作者:
Liang, Xuewu
;
Sun, Chenxia
;
Li, Chunpu
;
Yu, Haolan
;
Wei, Xiaohui
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Cerebellar ataxia and myeloradiculopathy associated with AP3B2 antibody: a case report and literature review
期刊论文
JOURNAL OF NEUROLOGY, 2021, 页码: 7
作者:
Mange, Liu
;
Haitao, Ren
;
Lixin, Zhou
;
Siyuan, Fan
;
Jing, Wang
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2021/06/09
Autoimmune
Cerebellar ataxia
Hydroxychloroquine Increased Anxiety-Like Behaviors and Disrupted the Expression of Some Related Genes in the Mouse Brain
期刊论文
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 12, 页码: 10
作者:
Xu, Hang
;
Zhang, Xiang Yang
;
Wang, Wei Wen
;
Wang, Jiesi
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2021/06/09
hydroxychloroquine
anxiety
BDNF
IL-1β
CRH
SLC6a4
AIF1
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
discoveryandbiologicalevaluationofn372methoxy44methylpiperazin1ylphenylamino4methyl2oxo2hpyrimido45d13oxazin14hylphenylacrylamideaspotentbrutonstyrosinekinaseinhibitors
期刊论文
actapharmacologicasinica, 2020, 卷号: 41, 期号: 3, 页码: 415
作者:
Lai Mengzhen
;
Song Peiran
;
Dou Dou
;
Diao Yanyan
;
Tong Linjiang
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton’s tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Donepezil, a drug for Alzheimer's disease, promotes oligodendrocyte generation and remyelination
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 11, 页码: 1386-1393
作者:
Cui, Xue
;
Guo, Yu-e
;
Fang, Jia-hui
;
Shi, Chang-jie
;
Suo, Na
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2020/07/01
donepezil
aricept
oligodendrocyte
oligodendrocyte progenitor cell
differentiation
myelin sheaths
remyelination
CNS demyelinating disorders
multiple sclerosis
Identification of new NIK inhibitors by discriminatory analysis-based molecular docking and biological evaluation
期刊论文
ARCHIV DER PHARMAZIE, 2019, 卷号: 352, 期号: 7, 页码: 9
作者:
Cheng, Gang
;
Mei, Xiao-Bing
;
Yan, You-You
;
Chen, Jing
;
Zhang, Bo
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/07/01
antiproliferation activity
inhibitors
NF-kappa B inducing kinase
virtual screen
Thyroid disorders in patients with systemic sclerosis: A systematic review and meta-analysis
期刊论文
AUTOIMMUNITY REVIEWS, 2019, 卷号: 18, 期号: 6
作者:
Yao, Qiuming
;
Song, Zhenyu
;
Wang, Bin
;
Zhang, Jin-an
;
Mu, Kaida
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/12/05
Systemic sclerosis
Autoimmune thyroid disease
Thyroid dysfunction
Risk factor
Prevalence
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