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Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity
期刊论文
ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22
作者:
Hu, Lin
;
Chen, Fuxian
;
Wu, Chao
;
Wang, Jun
;
Chen, Si-si
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/18
Structure-Based Virtual Screening and Identification of Potential Inhibitors of SARS-CoV-2 S-RBD and ACE2 Interaction
期刊论文
FRONTIERS IN CHEMISTRY, 2021, 卷号: 9, 页码: 12
作者:
Xiong, Jiacheng
;
Xiang, Yusen
;
Huang, Ziming
;
Liu, Xiaohong
;
Wang, Mengge
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  |  
浏览/下载:41/0
  |  
提交时间:2021/12/01
SARS-CoV-2
angiotensin-converting enzyme 2 (ACE2)
spike protein receptor-binding domain (S-RBD)
structure-based virtual screening
protein-protein interaction (PPI) inhibitors
Synthesis and Protein Tyrosine Phosphatase 1B (PTP1B) Inhibitory Activity Evaluation of Novel Arylaminoacetylhydrazone Derivatives Containing Carbazole Moiety
期刊论文
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 41, 期号: 8, 页码: 3157-3170
作者:
Li Yingjun
;
Lin Ledi
;
Jin Kun
;
Gao Lixin
;
Sheng Li
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/11/04
protein tyrosine phosphatase 1B (PTP1B) inhibitor
carbazole
arylaminoacetylhydrazone
synthesis
molecular docking
An invertebrate gene encoding a Mab21-containing protein involves in antiviral response through regulating the STING pathway
期刊论文
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 卷号: 121, 页码: 10
作者:
Li, Shihao
;
Yang, Feifei
;
Wang, Fuxuan
;
Lv, Xinjia
;
Li, Fuhua
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  |  
浏览/下载:28/0
  |  
提交时间:2021/12/07
Mab21-containing protein
cGAS-STING pathway
WSSV
Antiviral response
Penaeid shrimp
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:
Wang, Yi
;
Fang, Sui
;
Wu, Yan
;
Cheng, Xi
;
Zhang, Lei-ke
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  |  
浏览/下载:105/0
  |  
提交时间:2021/08/17
SARS-CoV-2
envelope protein (2-E)
cation channel
high-throughput screening (HTS)
anti-virus
Molecular Dynamics Simulations Reveal the Modulated Mechanism of STING Conformation
期刊论文
INTERDISCIPLINARY SCIENCES-COMPUTATIONAL LIFE SCIENCES, 2021, 页码: 15
作者:
Chen, Li
;
Zhao, Shuang
;
Zhu, Yanyan
;
Liu, Yongsheng
;
Li, Huiyu
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  |  
浏览/下载:26/0
  |  
提交时间:2021/08/17
STING
Small molecule
Binding site
Modulated mechanism
Molecular dynamics simulation
pi-pi stacking interaction
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
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  |  
浏览/下载:78/0
  |  
提交时间:2021/08/17
A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors
期刊论文
Bioorganic Chemistry, 2021, 卷号: 116, 期号: 7, 页码: 2341-2363
作者:
X. J. Yin
;
L. T. Chen
;
S. W. Yuan
;
L. Liu and Z. Z. Gao
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2022/06/13
Structural basis for the inhibition of SARS-CoV2 main protease by Indian medicinal plant-derived antiviral compounds
期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2020, 页码: 9
作者:
Saravanan, Konda Mani
;
Zhang, Haiping
;
Senthil, Renganathan
;
Vijayakumar, Kevin Kumar
;
Sounderrajan, Vignesh
收藏
  |  
浏览/下载:118/0
  |  
提交时间:2020/12/10
SARS-CoV2
main protease
medicinal plants
molecular docking and dynamics
drug design
Suppression of innate immune signaling molecule, MAVS, reduces radiation-induced bystander effect
期刊论文
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY, 2020, 页码: 9
作者:
Jia, Rong
;
Chen, Yaxiong
;
Jia, Cong
;
Hu, Burong
;
Du, Yarong
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/12/15
MAVS
irradiation
ROS
RIBE
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