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上海药物研究所 [37]
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兰州大学 [3]
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H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA
期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019, 卷号: 520, 期号: 1, 页码: 93-98
作者:
Li, Fengli
;
Wang, Jing
;
Wu, Ning
;
Zhang, Hua
;
Li, Zheng
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/03/20
5-FU
Drug resistance
STAT3
Hepatocellular carcinoma
MCL-1
PUMA
Design, synthesis, and biological evaluation of indole carboxylic acid esters of podophyllotoxin as antiproliferative agents
期刊论文
Medicinal Chemistry Research, 2019, 卷号: Vol.28 No.1, 页码: 81-94
作者:
Lei Zhang
;
Xian Zeng
;
Xiaodong Ren
;
Nengyin Tao
;
Chengli Yang
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2019/02/25
Podophyllotoxin
Indole
carboxylic
acid
Anti-MDR
activity
Apoptosis
Autophagy
New tanshinone I derivatives S222 and S439 similarly inhibit topoisomerase I/II but reveal different p53-dependency in inducing G2/M arrest and apoptosis
期刊论文
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 154, 页码: 255-264
作者:
Tian, Qian-Ting
;
Ding, Chun-Yong
;
Song, Shan-Shan
;
Wang, Ying-Qing
;
Zhang, Ao
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  |  
浏览/下载:40/0
  |  
提交时间:2019/01/08
Tanshinone-1
S222
S439
Anticancer targets
DNA topoisomerases
P53
Novel Nitric Oxide Donors of Phenylsulfonylfuroxan and 3-Benzyl Coumarin Derivatives as Potent Antitumor Agents
期刊论文
ACS MEDICINAL CHEMISTRY LETTERS, 2018, 卷号: 9, 期号: 5, 页码: 502-506
作者:
Guo, Yalan
;
Wang, Yujie
;
Li, Haihong
;
Wang, Ke
;
Wan, Qi
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  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
Phenylsulfonylfuroxan
3-benzyl coumarin
anticancer
multidrug resistance
P-gp overexpression
Identification of serine 119 as an effective inhibitor binding site of m. tuberculosis ubiquitin-like protein ligase pafa using purified proteins and m. smegmatis
期刊论文
Ebiomedicine, 2018, 卷号: 30, 页码: 225-236
作者:
Jiang, He-Wei
;
Czajkowsky, Daniel M.
;
Wang, Tao
;
Wang, Xu-De
;
Wang, Jia-bin
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2019/05/08
M. tuberculosis
Pupylation
Pafa
4-(2-aminoethyl) benzenesulfonyl fluoride
ES2 enhances the efficacy of chemotherapeutic agents in ABCB1-overexpressing cancer cells in vitro and in vivo
期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 页码: 388-399
作者:
Fang, Yanfen
;
Sun, Juanjuan
;
Zhong, Xing
;
Hu, Rui
;
Gao, Jie
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  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
MDR
ABCB1
Jatrophane diterpenoid ester
Chemotherapeutic agents
Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 146, 期号: 2, 页码: 157-170
作者:
Hu, R (Hu, Rui)
;
Gao, J (Gao, Jie)
;
Rozimamat, R (Rozimamat, Rushangul)
;
Aisa, HA (Aisa, Haji Akber)
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2018/05/15
Euphorbia Sororia
Jatrophane Diterpenoids
Multidrug Resistance Reversers
P-glycoprotein Modulators
Structure-activity Relationship
Mechanisms
ES2 enhances the efficacy of chemotherapeutic agents in ABCB1-overexpressing cancer cells in vitro and in vivo
期刊论文
PHARMACOLOGICAL RESEARCH, 2018, 卷号: 129, 期号: 3, 页码: 388-399
作者:
Fang, YF (Fang, Yanfen)
;
Sun, JJ (Sun, Juanjuan)
;
Zhong, X (Zhong, Xing)
;
Hu, R (Hu, Rui)
;
Gao, J (Gao, Jie)
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2018/05/07
Mdr
Abcb1
Jatrophane Diterpenoid Ester
Chemotherapeutic Agents
Pyramidatine (Z88) Sensitizes Vincristine-Resistant Human Oral Cancer (KB/VCR) Cells to Chemotherapeutic Agents by Inhibition of P-glycoprotein
期刊论文
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2018, 卷号: 18, 期号: 2, 页码: 286-294
作者:
Liu, Zulong
;
Zhu, Hengrui
;
Qu, Shijin
;
Tang, Lisha
;
Cao, Lihuan
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2019/01/08
Aglaia perviridis
multi-drug resistance
KB/VCR cells
P-gp
reversal agent
pyramidatine
Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2017, 卷号: 27, 期号: 44
作者:
Zhao, Pengfei
;
Yin, Weimin
;
Wu, Aihua
;
Tang, Yisi
;
Wang, Jinyu
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
albumin nanoparticles
combination therapy
mannose receptors
multidrug resistance
SPARC
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