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上海药物研究所 [11]
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期刊论文 [73]
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Expression, purification and characterization of the second DUSP domain of deubiquitinase USP20/VDU2
期刊论文
PROTEIN EXPRESSION AND PURIFICATION, 2021, 卷号: 181, 页码: 6
作者:
Hu, Shuwei
;
Chen, Xiaoyu
;
Zhu, Mengying
;
Hu, Huifang
;
Zhou, Chen
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/05/24
Deubiquitinase
USP20
DUSP domain
NMR
A genetically encoded small-size fluorescent pair reveals allosteric conformational changes of G proteins upon its interaction with GPCRs by fluorescence lifetime based FRET
期刊论文
CHEMICAL COMMUNICATIONS, 2020, 卷号: 56
作者:
Shi, Pan
;
Zhang, Yanan
;
Lv, Pei
;
Fang, Wei
;
Ling, Shenglong
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/10/26
DeepCPI: A Deep Learning-based Framework for Large-scale in silico Drug Screening
期刊论文
GENOMICS PROTEOMICS & BIOINFORMATICS, 2019, 卷号: 17, 期号: 5, 页码: 478-495
作者:
Wan, Fangping
;
Zhu, Yue
;
Hu, Hailin
;
Dai, Antao
;
Cai, Xiaoqing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
Deep learning
Machine learning
Drug discovery
In silico drug screening
Compound-protein interaction prediction
Berberine promotes the recruitment and activation of brown adipose tissue in mice and humans
期刊论文
CELL DEATH & DISEASE, 2019, 卷号: 10, 页码: 18
作者:
Wu, Lingyan
;
Xia, Mingfeng
;
Duan, Yanan
;
Zhang, Lina
;
Jiang, Haowen
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  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
Identification of higenamine as a novel alpha(1)-adrenergic receptor antagonist
期刊论文
2019, 卷号: 33, 期号: 3, 页码: 708-717
作者:
Zhang, Nana
;
Qu, Kai
;
Wang, Minjie
;
Yin, Qian
;
Wang, Wenjing
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/01/03
antagonism
blood pressure
higenamine hydrochloride
vasorelaxation
alpha(1)-adrenoceptor
The cholinergic and adrenergic autocrine signaling Pathway Mediates immunomodulation in Oyster Crassostrea gigas
期刊论文
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9
作者:
Liu, Zhaoqun
;
Wang, Lingling
;
Lv, Zhao
;
Zhou, Zhi
;
Wang, Weilin
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2018/09/06
Crassostrea Gigas
Autocrine/paracrine
Hemocyte
Neurotransmitter
Membrane Receptor
Immune Regulation
AMP-Activated Protein Kinase (AMPK) Regulates Energy Metabolism through Modulating Thermogenesis in Adipose Tissue
期刊论文
FRONTIERS IN PHYSIOLOGY, 2018, 卷号: 9
作者:
Wu, Lingyan
;
Zhang, Lina
;
Li, Bohan
;
Jiang, Haowen
;
Duan, Yanan
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2019/01/08
AMP-activated protein kinase
thermogenesis
energy metabolism
A-769662
white adipose browning
PGC-1 alpha
Testosterone-induced benign prostatic hyperplasia rat and dog as facile models to assess drugs targeting lower urinary tract symptoms
期刊论文
PLOS ONE, 2018, 卷号: 13, 期号: 1
作者:
Li, Jing
;
Tian, Yanxin
;
Guo, Shimeng
;
Gu, Haifeng
;
Yuan, Qianting
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/01/08
Silence of alpha 1-Antitrypsin Inhibits Migration and Proliferation of Triple Negative Breast Cancer Cells
期刊论文
MEDICAL SCIENCE MONITOR, 2018, 卷号: 24
作者:
Zhao, Zhijing
;
Ma, Junfeng
;
Mao, Ying
;
Dong, Liying
;
Li, Siqi
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/12/04
Adrenergic alpha-1 Receptor Antagonists
Phosphatidylinositol 3-Kinase
Transcellular Cell Migration
Trip Negative Breast Neoplasms
Dexmedetomidine attenuates renal fibrosis via alpha 2-adrenergic receptor-dependent inhibition of cellular senescence after renal ischemia/reperfusion
期刊论文
LIFE SCIENCES, 2018, 卷号: 207, 页码: 1-8
作者:
Li, Qijian
;
Chen, Chaojin
;
Chen, Xi
;
Han, Mingming
;
Li, Juan
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/11
Dexmedetomidine
Renal ischemia reperfusion
Fibrosis
Senescence
Inflammation
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