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上海药物研究所 [13]
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厦门大学 [1]
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期刊论文 [26]
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2017 [3]
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浏览/检索结果:
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Discovery of a potent and selective adenylyl cyclase type 8 agonist by docking-based virtual screening
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 2, 页码: 7
作者:
Weng, Zhiying
;
Xu, Guowei
;
Chen, Dingyuan
;
Yang, Yaqing
;
Song, Gao
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/03/18
Adenylyl cyclases
Homology modeling
Consensus scoring
Molecular dynamics simulation
Virtual screening
Biological evaluation
Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal
期刊论文
EMBO MOLECULAR MEDICINE, 2017, 卷号: 9, 期号: 11, 页码: 1521-1536
作者:
Zhang, Lei
;
Kibaly, Cherkaouia
;
Wang, Yu-Jun
;
Xu, Chi
;
Song, Kyu Young
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/01/08
lentivirus injection
locus coeruleus
naloxone-precipitated opiate withdrawal
opiate addiction
Src-mediated phosphorylation of MOR at Tyr(336)
DMT efficiently inhibits hepatic gluconeogenesis by regulating the G alpha q signaling pathway
期刊论文
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 2017, 卷号: 59, 期号: 2, 页码: 151-169
作者:
Zhou, Ting-Ting
;
Ma, Fei
;
Shi, Xiao-Fan
;
Xu, Xin
;
Du, Te
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
Gaq signaling
hepatic gluconeogenesis
protein kinase B (AKT)
type 2 diabetes mellitus (T2DM)
Soluble adenylyl cyclase mediates mitochondrial pathway of apoptosis and ATP metabolism in oyster Crassostrea gigas exposed to elevated CO2
期刊论文
FISH & SHELLFISH IMMUNOLOGY, 2017, 卷号: 66, 页码: 140-147
作者:
Wang, Xiudan
;
Wang, Mengqiang
;
Xu, Jiachao
;
Jia, Zhihao
;
Liu, Zhaoqun
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2017/10/09
Crassostrea Gigas
Elevated Co2
Apoptosis
Atp
Soluble Adenylyl Cyclase
Mitochondria
The structural basis of the dominant negative phenotype of the G alpha(i1)beta(1)gamma(2) G203A/A326S heterotrimer
期刊论文
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 9, 页码: 1259-1272
作者:
Liu, Ping
;
Jia, Ming-zhu
;
Zhou, X. Edward
;
De Waal, Parker W.
;
Dickson, Bradley M.
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
dominant negative
G alpha(i1)beta(1)gamma(2) heterotrimer
G203A
A326S
crystal structure
GPCR
GDP
G-Protein alpha-Subunit Gs alpha Is Required for Craniofacial Morphogenesis
期刊论文
PLOS ONE, 2016
作者:
Lei, Run
;
Zhang, Ke
;
Wei, Yanxia
;
Chen, Min
;
Weinstein, Lee S.
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2017/01/16
Calcium activated adenylyl cyclase AC8 but not AC1 is required for prolonged behavioral anxiety
期刊论文
MOLECULAR BRAIN, 2016, 卷号: 9
作者:
Bernabucci, Matteo
;
Zhuo, Min
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/11/26
Anxiety
Elevated plus-maze
N-Methyl-D-aspartate
Retest
Adenylyl cyclase 8
Memory
Anterior cingulate cortex
Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells
期刊论文
diabetologia, 2015
Dou, Haiqiang
;
Wang, Changhe
;
Wu, Xi
;
Yao, Lijun
;
Zhang, Xiaoyu
;
Teng, Sasa
;
Xu, Huadong
;
Liu, Bin
;
Wu, Qihui
;
Zhang, Quanfeng
;
Hu, Meiqin
;
Wang, Yeshi
;
Wang, Li
;
Wu, Yi
;
Shang, Shujiang
;
Kang, Xinjiang
;
Zheng, Lianghong
;
Zhang, Jin
;
Raoux, Matthieu
;
Lang, Jochen
;
Li, Qing
;
Su, Jing
;
Yu, Xiao
;
Chen, Liangyi
;
Zhou, Zhuan
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2015/11/11
Adenylyl cyclase 8
Ca2+
Pancreatic beta cell
Protein kinase A
Vesicle pool
PROTEIN-KINASE-A
CA2+-INDUCED CA2+ RELEASE
ADRENAL CHROMAFFIN CELLS
CYCLIC-AMP
B-CELLS
CAMP
GLUCOSE
EXOCYTOSIS
EXPRESSION
ISLETS
Calcium influx activates adenylyl cyclase 8 for sustained insulin secretion in rat pancreatic beta cells
期刊论文
DIABETOLOGIA, 2015, 卷号: 58, 期号: 2, 页码: 324-333
作者:
Dou, Haiqiang
;
Wang, Changhe
;
Wu, Xi
;
Yao, Lijun
;
Zhang, Xiaoyu
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/17
Adenylyl cyclase 8
Ca2+
Pancreatic beta cell
Protein kinase A
Vesicle pool
Overexpression of the Type 1 Adenylyl Cyclase in the Forebrain Leads to Deficits of Behavioral Inhibition
期刊论文
JOURNAL OF NEUROSCIENCE, 2015, 卷号: 35, 期号: 1
作者:
Chen, Xuanmao
;
Cao, Hong
;
Saraf, Amit
;
Zweifel, Larry S.
;
Storm, Daniel R.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/19
ADHD
behavioral inhibition
hyperactivity
impulsivity
sociability
type I adenylyl cyclase
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