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Discovery of trisubstituted nicotinonitrile derivatives as novel human GCN5 inhibitors through AlphaScreen-based high throughput screening 期刊论文
RSC ADVANCES, 2019, 卷号: 9, 期号: 9, 页码: 4917-4924
作者:  Tao, Hongru;  Wang, Jun;  Lu, Wenchao;  Zhang, Rukang;  Xie, Yiqian
收藏  |  浏览/下载:41/0  |  提交时间:2020/07/01
Identification of a cellularly active SIRT6 allosteric activator 期刊论文
NATURE CHEMICAL BIOLOGY, 2018, 卷号: 14, 期号: 12, 页码: 1118-+
作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin
收藏  |  浏览/下载:90/0  |  提交时间:2019/01/08
Expression of acetyl-histone H3 and acetyl-histone H4 in dorsal root ganglion and spinal dorsal horn in rat chronic pain models 期刊论文
LIFE SCIENCES, 2018, 卷号: 211, 页码: 182-188
作者:  Liang, Lingli;  Tao, Yuan-Xiang
收藏  |  浏览/下载:9/0  |  提交时间:2019/11/19
Probucol ameliorates renal injury in diabetic nephropathy by inhibiting the expression of the redox enzyme p66Shc 期刊论文
Redox Biology, 2017, 卷号: 13, 页码: 482-497
作者:  Yang, Shikun;  Zhao, Li;  Han, Yachun;  Liu, Yu;  Chen, Chao
收藏  |  浏览/下载:24/0  |  提交时间:2019/12/03
DN  diabetic nephropathy  ROS  reactive oxygen species  HG  high-glucose  SIRT1  sirtuin-1  Ac-H3  acetyl-histone H3  STZ  streptozotocin  AMPK  AMP-activated protein kinase  ECM  extracellular matrix  Nox2  NADPH oxidase 2  EMT  tubular epithelial-mesenchymal transition  DAPI  4′,6-diamidino-2-phenylindole 9  DHE  dihydroethidium  NDRD  non-diabetic renal disease  H&E  hematoxylin-eosin  PAS  periodic acid-Schiff  PASM  periodic acid-silver methenamine  IHC  immunohistochemistry  MDA  malondialdehyde  ChIP  chromatin immunoprecipitation  TC  total cholesterol  BUN  blood urea nitrogen  FN  fibronectin  HBA1C  glycosylated hemoglobin  Scr  serum creatinine  TG  triglyceride  Probucol  Renal injury  Diabetic nephropathy  p66Shc  
Tetrahydroisoquinolines as novel histone deacetylase inhibitors for treatment of cancer 期刊论文
ACTA PHARMACEUTICA SINICA B, 2016, 卷号: 6, 期号: 1, 页码: 93-99
作者:  Chen, Danqi;  Shen, Aijun;  Fang, Guanghua;  Liu, Hongchun;  Zhang, Minmin
收藏  |  浏览/下载:19/0  |  提交时间:2019/01/08
Catalytic Mechanism of Histone Acetyltransferase p300: From the Proton Transfer to Acetylation Reaction 期刊论文
JOURNAL OF PHYSICAL CHEMISTRY B, 2014, 卷号: 118, 期号: 8, 页码: 2009-2019
作者:  Zhang, Xinlei;  Ouyang, Sisheng;  Kong, Xiangqian;  Liang, Zhongjie;  Lu, Junyan
收藏  |  浏览/下载:28/0  |  提交时间:2019/01/08
The expression patterns and correlations of claudin-6, methy-CpG binding protein 2, DNA methyltransferase 1, histone deacetylase 1, acetyl-histone H3 and acetyl-histone H4 and their clinicopathological significance in breast invasive ductal carcinomas 期刊论文
DIAGNOSTIC PATHOLOGY, 2012, 卷号: 7
作者:  Xu, Xiaoming;  Jin, Huiying;  Liu, Yafang;  Liu, Li;  Wu, Qiong
收藏  |  浏览/下载:3/0  |  提交时间:2019/12/05
The expression patterns and correlations of claudin-6, methy-CpG binding protein 2, DNA methyltransferase 1, histone deacetylase 1, acetyl-histone H3 and acetyl-histone H4 and their clinicopathological significance in breast invasive ductal carcinomas 期刊论文
DIAGNOSTIC PATHOLOGY, 2012, 卷号: 7
作者:  Xu, Xiaoming;  Jin, Huiying;  Liu, Yafang;  Liu, Li;  Wu, Qiong
收藏  |  浏览/下载:5/0  |  提交时间:2019/12/05
组蛋白去乙酰化酶抑制剂SAHA诱导多发性骨髓瘤细胞株U266细胞凋亡及其机制研究 学位论文
2012, 2012
于涛
收藏  |  浏览/下载:3/0  |  提交时间:2016/02/14
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate 期刊论文
SCIENCE, 2009, 卷号: 325, 期号: 5945, 页码: 1254-1257
作者:  Hait, Nitai C.;  Allegood, Jeremy;  Maceyka, Michael;  Strub, Graham M.;  Harikumar, Kuzhuvelil B.
收藏  |  浏览/下载:26/0  |  提交时间:2019/01/08


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