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(3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one attenuates cardiac dysfunction via the apelin/APJ signaling pathway
期刊论文
MOLECULAR MEDICINE REPORTS, 2019, 卷号: 19, 期号: 6
作者:
Ding, Mei
;
Guan, Lianyue
;
Zhang, Chunmei
;
Yang, Ping
;
Yang, Hailing
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/12/05
myocardial infarction
(3R)-5
6
7-trihydroxy-3-isopropyl-3-methylisochroman-1-one
cardiomyocyte apoptosis
apelin
apelin receptor
Targeting drugs to APJ receptor: From signaling to pathophysiological effects
期刊论文
Journal of Cellular Physiology, 2019, 卷号: 234, 期号: 1, 页码: 61-74
作者:
Huang, Zhen
;
He, Lu
;
Chen, Zhe*
;
Chen, Linxi*
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/27
agonists
antagonists
apelin
APJ
compounds
Elabela
Apj(+) Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target
期刊论文
CELL REPORTS, 2018, 卷号: 25, 期号: 5, 页码: 1241-+
作者:
Zhao, Huan
;
He, Lingjuan
;
Li, Yan
;
Pu, Wenjuan
;
Liu, Qiaozhen
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2019/04/28
Protein-coupled Receptor
In-vivo
Apelin-apj
Endothelial-cells
Angiogenic Factor
Genetic Ablation
Transgenic Mice
Toxin Gene
T-cells
Expression
Low-Density Lipoprotein Receptor-Related Protein 6 Is Essential for Trophoblast Survival and Invasion.
期刊论文
Reproductive sciences (Thousand Oaks, Calif.), 2018
作者:
Li, Lei
;
Wan, Jipeng
;
Xue, Jing
;
Li, Hongyan
;
Wang, Shan
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/11
Angiotensin II receptor blockers for the treatment of portal hypertension in patients with liver cirrhosis: a systematic review and meta-analysis of randomized controlled trials
期刊论文
IRISH JOURNAL OF MEDICAL SCIENCE, 2018, 卷号: 187, 期号: 4, 页码: 1-10
作者:
Yao, Huijing
;
Zhang, Chunqing
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2019/12/11
Angiotensin II receptor blockers
Cirrhosis
Meta-analysis
Portal hypertension
Profiling the pattern of the human T-cell receptor gammadelta complementary determinant region 3 repertoire in patients with lung carcinoma via high-throughput sequencing analysis.
期刊论文
Cellular & molecular immunology, 2018
作者:
Chen, Hui
;
Zou, Mingjin
;
Teng, Da
;
Hu, Yu
;
Zhang, Jianmin
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/11
Biological functions of Elabela, a novel endogenous ligand of APJ receptor
期刊论文
Journal of Cellular Physiology, 2018, 卷号: 233, 期号: 9, 页码: 6472-6482
作者:
Xu, Jin
;
Chen, Linxi
;
Jiang, Zhisheng*
;
Li, Lanfang*
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
apelin
APJ
elabela
The Role of the Apelin/APJ System in the Regulation of Liver Disease
期刊论文
FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8
作者:
Lv, Xinrui[1]
;
Kong, Jing[2]
;
Chen, Wei-Dong[3]
;
Wang, Yan-Dong[4]
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/12/23
Apelin
APJ
liver disease
peptide
angiotensin II receptor like-1
The endoplasmic reticulum stress-autophagy pathway is involved in apelin-13-induced cardiomyocyte hypertrophy in vitro
期刊论文
Acta Pharmacologica Sinica, 2017, 卷号: 38, 期号: 12, 页码: 1589-1600
作者:
Xie, Feng
;
Wu, Di
;
Huang, Shi-Fang
;
Cao, Jian-Gang
;
Li, He-Ning
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2019/12/27
myocardial hypertrophy
apelin
APJ receptor
ROS
NOX4
ER stress
autophagy
reticulophagy
Apelin/APJ system: A bifunctional target for cardiac hypertrophy
期刊论文
International Journal of Cardiology, 2017, 卷号: 230, 页码: 164-170
作者:
Lu, Liqun
;
Wu, Di
;
Li, Lanfang*
;
Chen, Linxi*(陈临溪)
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/27
Apelin/APJ system
Cardiac hypertrophy
Oxidative stress
Obesity
Hypertension
Myocardial infarction
AT1R
angiotensin II type 1 receptor
Ang II
angiotensin II
PCSK3
proprotein convertase subtilisin/kexin3
5-HT
serotonin
TNF-α
tumor necrosis factor-a
HW/BW
the ratio of heart weight/body weight
ANP
atrial natriuretic peptide
LV
left ventricular
ANF
atrial natriuretic factor
TGF-β1
transforming growth factor beta1
ROS
reactive oxygen species
β-MHC
beta-myosin heavy chain
HFD
high-fat diet
ER
endoplasmic reticulum
FA
fatty acid
MI
myocardial infarction
ACE2
angiotensin-converting enzyme 2
LVH
left ventricular hypertrophy
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