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浏览/检索结果: 共6条，第1-6条 帮助 已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Successful treatment with osimertinib and its subsequent resistance mechanism in a patient with non-small-cell lung cancer harboring acquired EGFR T790M mutation after recovery from AC0010-induced interstitial lung disease 期刊论文 2019, 卷号: 12, 页码: 5545-5549 作者:  Wang, Hanping;  Zhang, Li;  Shi, Xiaohua;  Zhang, Xiaotong;  Si, Xiaoyan 收藏  |  浏览/下载：10/0  |  提交时间：2020/01/03 osimertinib  AC0010  interstitial lung disease  resistance mechanism  transformation  large-cell neuroendocrine carcinoma   First-in-Human Phase I Study of AC0010, a Mutant-Selective EGFR Inhibitor in Non-Small Cell Lung Cancer: Safety, Efficacy, and Potential Mechanism of Resistance 期刊论文 2018, 卷号: 13, 期号: 7, 页码: 968-977 作者:  Ma Yuxiang;  Zheng Xin;  Zhao Hongyun;  Fang Wenfeng;  Zhang Yang 收藏  |  浏览/下载：2/0  |  提交时间：2020/01/03 EGFR  T790M  cell-free DNA  next-generation sequencing   Phase I/II Study of AC0010, Mutant Selective EGFR Inhibitor, in Non-Small Cell Lung Cancer (NSCLC) Patients with EGFR T790M Mutation 期刊论文 2017, 卷号: 12, 期号: 1, 页码: S437-S438 作者:  Wu, Yi Long;  Zhou, Qing;  Liu, Xiaoqing;  Zhang, Li;  Zhou, Jianying 收藏  |  浏览/下载：3/0  |  提交时间：2020/01/03 Phase I/II study  NSCLC  T790M  AC0010   Development of an UPLC-MS/MS method for quantification of Avitinib (AC0010) and its five metabolites in human cerebrospinal fluid: Application to a study of the blood-brain barrier penetration rate of non-small cell lung cancer patients 期刊论文 2017, 卷号: 139, 页码: 205-214 作者:  Wang Weicong;  Zheng Xin;  Wang Hanping;  Wang Lu;  Jiang Ji 收藏  |  浏览/下载：3/0  |  提交时间：2020/01/04 AC0010  Avitinib  UPLC-MS/MS  EGFR-TKI  NSCLC  Cerebrospinal fluid   An LC-MS/MS method for quantification of AC0010, a novel mutant-selective epidermal growth factor receptor (EGFR) inhibitor, and its metabolites in human plasma and the application to a pharmacokinetic study 期刊论文 2017, 卷号: 141, 页码: 9-18 作者:  Wang Lu;  Zheng Xin;  Wang Weicong;  Hu Pei;  Jiang Ji 收藏  |  浏览/下载：4/0  |  提交时间：2020/01/04 AC0010  EGFR TKI  LC–MS/MS  Method validation  Non-small-cell lung cancer  Pharmacokinetics   AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients 期刊论文 2016, 卷号: 15, 期号: 11, 页码: 2586-2597 作者:  Xu Xiao;  Mao Long;  Xu Wanhong;  Tang Wei;  Zhang Xiaoying 收藏  |  浏览/下载：6/0  |  提交时间：2020/01/04