MTT  3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-H-tetrazolium bromide  GG  Galangin  DDP  cisplatin  STAT3  signal transducers and activation of transcription  LC  Lung cancer  MDR  multidrug resistance  NSCL  Cnon-small cell lung cancer  Bcl-2  B-cell leukemia/lymphoma 2  Bax  bcl-2-like protein  TRAIL  TNF-related apoptosis-inducing ligand  NF-κB  nuclear factor kappa-light-chain-enhancer of activated B cells  IκBα  inhibitor of NF-κBα  Cyto-c  cytochrome c  Lung cancer  Galangin  Cisplatin  p-STAT3/p65  Bcl-2  

A1c  glycated hemoglobin  AACE  American Association of Clinical Endocrinologists  ACC  acetyl-CoA carboxylase  ADA  American Diabetes Association  Akt/PKB  tyrosine kinase/protein kinase B  AMP  adenosine monophosphate  AMPK  adenosine monophosphate-activated protein  Ang II  angiotensin II  ATP  adenosine triphosphate  BAT  brown adipose tissue  CHOP  CEBP-homologous protein  CEBP  CCAAT enhancer binding protein  CoA  coenzyme A  DPP  Diabetes Prevention Program  EASD  European Association for the Study of Diabetes  eNOS  endothelial nitric oxide synthase  ER  endoplasmic reticulum  FDA  Food and Drug Administration  FFA  free fatty acid  FOXO1  forkhead box protein O1  G6P  glucose 6-phosphate  GDM  gestational diabetes mellitus  GIPR  glucose-dependent insulinotropic polypeptide receptor  GLP-1R  glucagon-like peptide-1 receptor  GLUT1  glucose transporter-1  GLUT4  glucose transporter type 4  GLUTs  glucose transporters  G6P  glucose 6-phosphate, glucose transporter-1  GPR40  G protein-coupled receptor 40  HbA1c  hemoglobin A1c  HGP  hepatic glucose production  HSL  hormone sensitive lipase  IL-6  interleukin 6  INS-1  insulinoma cells in rat  IR  insulin resistance  IRS-1  insulin receptor substrate 1  JNK  c-Jun. N-terminal kinase  Kir6.2  inwardly rectifying potassium/kalium channel  LDs  lipid droplets  LDL  low density lipoprotein  LV  left ventricular  MIN6 cells  mouse insulinoma cells  MAPK  mitogen-activated protein kinases  mPTP  mitochondrial permeability transition pore opening  mTOR  mammalian target of rapamycin  NADPH  nicotinamide adenine dinucleotide phosphate  NF-kappaB  nuclear factors-kappa B  NIT-1 cells  insulinoma cells  p70S6K  p70 ribosomal S6 kinase  PA  palmitic acid  NOS  NADPH oxidase  p38 MAPK  p38 mitogen-activated protein kinase  PA  palmitic acid  PCOS  polycystic ovary syndrome  PGC-1α  peroxisome proliferator-activated receptor-g coactivator-1α  PI3K  phosphatidylinositol 3-kinase  PKB  protein kinase B  PKC  protein kinase C  PPARα  peroxisome-proliferator activated receptor α  PTP  permeability transition pore  RCT  randomized controlled trial  RISK  reperfusion injury salvage kinase  ROS  reactive oxygen species  SERCA2  reticulum sarcoplasmic Ca2 +-ATPase  RISK  reperfusion injury salvage kinase  Smad3  mothers against decapentaplegic homolog 3  SRC-2  steroid receptor coactivator 2  T1DM  Type 1 diabetes mellitus  T2DM  Type 2 diabetes mellitus  TGFβ1  transforming growth factor β1  TLR4  Toll-like receptor  TNF-α  tumor necrosis factor α  TR4  testicular receptor 4  UKPDS  United Kingdom Prospective Diabetes Study  VLDL  very low density lipoprotein  Metformin  Pancreatic β Cells  Heart failure  Insulin sensitizer  

Lymphocyte-specific helicase (LSH)  Epithelial-mesenchymal transition (EMT)  E-Cadherin  ZO-1  Vimentin  Tricarboxylic acid cycle intermediates  Inhibitor of nuclear factor kappa-B kinase alpha (IKKα)  G9a  

HCC  hepatocellular carcinoma  ATO  arsenic trioxide  APL  acute promyelocytic leukemia  PML  promyelocytic leukemia protein  RARα  retinoic acid receptor α  ALDH3A1  aldehyde dehydrogenase 3 family member A1  qRT-PCR  quantitative real-time reverse transcriptase polymerase chain reaction  TMA  tissue microarray  OS  overall survival  TTR  time to recurrence  DMEM  Dulbecco's modified Eagle's medium  CB7  1-[(4-fluorophenyl) sulfonyl]-2-methyl-1H-benzimidazole  siRNA  small interfering RNA  shRNA  small hairpin RNA  GFP  green fluorescent protein  MTT  3-(4,5-dimethylthiazol2-yl)-2,5-diphenyltetrazolium bromide  ChIP  chromatin immunoprecipitation  ORF  open reading frame  ROS  reactive oxygen species  DCFH-DA  2,7-dichlorfluorescein-diacetate  AFP  α-fetoprotein  ALT  alanine aminotransferase  TTP  time to progression  GO  gene ontology  NFκB  nuclear factor kappa-light-chain-enhancer of activated B cells  Bcl-2  B-cell lymphoma 2  Promyelocytic leukemia protein  Aldehyde dehydrogenase 3 family member A1  Reactive oxygen species  Tumor growth  Drug resistance  

Mesial temporal lobe epilepsy  Myeloid-related protein 8  Toll-like receptor 4  Nuclear factor-kappa B  Interleukin-1 beta