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上海药物研究所 [5]
复旦大学上海医学院 [5]
中国医学科学院 北京... [4]
四川大学 [2]
上海中医药大学 [2]
合肥物质科学研究院 [2]
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期刊论文 [25]
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Olaparib maintenance monotherapy in Chinese patients with platinum-sensitive relapsed ovarian cancer: China cohort from the phase III SOLO2 trial
期刊论文
ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 2022
作者:
Liu, Jihong
;
Yin, Rutie
;
Wu, Lingying
;
Zhu, Jianqing
;
Lou, Ge
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/05/05
BRCA mutation
China
olaparib
ovarian cancer
PARP inhibitor
The dual HDAC-PI3K inhibitor CUDC-907 displays single-agent activity and synergizes with PARP inhibitor olaparib in small cell lung cancer
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2020, 卷号: 39
作者:
Ma, Liying
;
Bian, Xing
;
Lin, Wenchu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/11/30
SCLC
PI3K
HDAC
CUDC-907
PARP1
Olaparib
DSB repair
Combination treatment
Olaparib induced senescence under P16 or P53 dependent manner in ovarian cancer
期刊论文
JOURNAL OF GYNECOLOGIC ONCOLOGY, 2019, 卷号: 30, 期号: 2
作者:
Wang, Zehua
;
Gao, Jianwen
;
Zhou, Jiabing
;
Liu, Haiou
;
Xu, Congjian
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2019/12/05
Olaparib
Senescence
Ovarian Neoplasms
MUS81 Inhibition Increases the Sensitivity to Therapy Effect in Epithelial Ovarian Cancer via Regulating CyclinB Pathway
期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 10
作者:
Zhong, Ailing
;
Zheng, Hui
;
Zhang, Hongqin
;
Sun, Jiajun
;
Shen, Jiabin
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2019/12/05
MUS81
CyclinB
Olaparib
DNA damage repair
EOC
SPAG5 upregulation contributes to enhanced c-MYC transcriptional activity via interaction with c-MYC binding protein in triple-negative breast cancer
期刊论文
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2019, 卷号: 12
作者:
Lv, Hong
;
Li, Ming
;
Li, Anqi
;
Zhou, Shuling
;
Yang, Wentao
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  |  
浏览/下载:10/0
  |  
提交时间:2019/12/05
SPAG5
MYCBP
Olaparib
C-MYC
Triple-negative breast cancer
Efficacy and safety of olaparib maintenance therapy in platinum-sensitive ovarian cancer patients with BRCA mutations: a meta-analysis on randomized controlled trials
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11
作者:
Deng, Hongyong
;
Li, Jiajia
;
Hu, Shaopu
;
Yang, Yanping
;
Ma, Jiao
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/12/05
olaparib
ovarian cancer
efficacy
adverse event
meta-analysis
Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors
期刊论文
Journal of enzyme inhibition and medicinal chemistry, 2019, 卷号: 34, 页码: 150-162
作者:
Gao Cheng-Zhi[1]
;
Dong Wei[2]
;
Cui Zhi-Wen[3]
;
Yuan Qiong[4]
;
Hu Xia-Min[5]
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2019/04/22
AChE
Alzheimer's Disease
BChE
Olaparib
PARP-1 inhibitor
Cyclin D1 silencing impairs DNA double strand break repair, sensitizes BRCA1 wildtype ovarian cancer cells to olaparib
期刊论文
Gynecologic Oncology, 2019, 卷号: Vol.152 No.1, 页码: 157-165
作者:
Qian Zhong
;
Zhongyi Hu
;
Qiao Li
;
Tao Yi
;
Jinke Li
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/02/25
BRCA
Cyclin
D1
Ovarian
cancer
Olaparib
Homologous
recombination
Synthesis, preliminarily biological evaluation and molecular docking study of new Olaparib analogues as multifunctional PARP-1 and cholinesterase inhibitors
期刊论文
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2019, 卷号: 34, 期号: 1
作者:
Gao, Cheng-Zhi
;
Dong, Wei
;
Cui, Zhi-Wen
;
Yuan, Qiong
;
Hu, Xia-Min
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/06
PARP-1 inhibitor
Olaparib
AChE
BChE
Alzheimer's Disease
Patient-reported outcomes in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer receiving olaparib versus chemotherapy in the OlympiAD trial
期刊论文
2019, 卷号: 120, 页码: 20-30
作者:
Robson Mark
;
Ruddy Kathryn J
;
Im Seock-Ah
;
Senkus Elżbieta
;
Xu Binghe
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/01/03
BRCA
Breast cancer
EORTC QLQ-C30
Health-related quality of life
Olaparib
OlympiAD
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