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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2016    专题：北京大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 RAB18, a protein associated with Warburg Micro syndrome, controls neuronal migration in the developing cerebral cortex 期刊论文 MOLECULAR BRAIN, 2016 Wu, Qinwei; Sun, Xiaqin; Yue, Weihua; Lu, Tianlan; Ruan, Yanyan; Chen, Tianda; Zhang, Dai 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 RAB18  Neuronal migration  Warburg Micro syndrome  GTPASE-ACTIVATING PROTEIN  OF-FUNCTION MUTATIONS  NONCATALYTIC SUBUNIT  BIPOLAR TRANSITION  MARTSOLF-SYNDROME  LIPID DROPLETS  MULTIPOLAR  POLARIZATION  TRAFFICKING  OUTGROWTH   Chromatin remodeling gene EZH2 involved in the genetic etiology of autism in Chinese Han population 期刊论文 NEUROSCIENCE LETTERS, 2016 Li, Jun; You, Yang; Yue, Weihua; Yu, Hao; Lu, Tianlan; Wu, Zhiliu; Jia, Meixiang; Ruan, Yanyan; Liu, Jing; Zhang, Dai; Wang, Lifang 收藏  |  浏览/下载：4/0  |  提交时间：2017/12/03 Autism  EZH2  Chromatin remodeling gene  Family-based association test  DE-NOVO MUTATIONS  SPECTRUM DISORDERS  NEURAL DEVELOPMENT  ASSOCIATION  EXPRESSION  METHYLTRANSFERASE  DIFFERENTIATION  REVEALS  CNTNAP2   Simultaneous generation of multi-gene knockouts in human cells 期刊论文 FEBS LETTERS, 2016 Zhou, Yuexin; Zhang, Hongmin; Wei, Wensheng 收藏  |  浏览/下载：3/0  |  提交时间：2017/12/03 CRISPR  knockout  nonhomologous end-joining  NUCLEASE-INDUCED MUTATIONS  ZINC-FINGER NUCLEASES  STRAND BREAK REPAIR  CRISPR-CAS9 SYSTEM  INSERTION SITES  DNA  CRISPR/CAS9  INTEGRATION  ENRICHMENT  EFFECTORS   iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers 期刊论文 SCIENTIFIC REPORTS, 2016 Wang, Meng; Wei, Liping 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/04 AMINO-ACID SUBSTITUTIONS  UNKNOWN CLINICAL-SIGNIFICANCE  PROTEIN FUNCTION  MISSENSE VARIANTS  SEQUENCE VARIANTS  DISEASE  MUTATIONS  ASSOCIATION  CONSTRAINT  DISCOVERY   Inability to activate Rac1-dependent forgetting contributes to behavioral inflexibility in mutants of multiple autism-risk genes 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2016 Dong, Tao; He, Jing; Wang, Shiqing; Wang, Lianzhang; Cheng, Yuqi; Zhong, Yi 收藏  |  浏览/下载：8/0  |  提交时间：2017/12/04 autism  forgetting  Rac1  behavioral flexibility  Drosophila  DE-NOVO MUTATIONS  TUBEROUS SCLEROSIS COMPLEX  LONG-TERM-MEMORY  SPECTRUM DISORDERS  ANGELMAN-SYNDROME  DROSOPHILA-MELANOGASTER  COGNITIVE FLEXIBILITY  SYNAPTIC PLASTICITY  UBIQUITIN LIGASE  REGULATES SLEEP   NEDD4L Protein Catalyzes Ubiquitination of PIK3CA Protein and Regulates PI3K-AKT Signaling 期刊论文 JOURNAL OF BIOLOGICAL CHEMISTRY, 2016 Wang, Zixi; Dang, Tingting; Liu, Tingting; Chen, She; Li, Lin; Huang, Song; Fang, Min 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/04 Akt PKB  E3 ubiquitin ligase  phosphatidylinositide 3-kinase (PI 3-kinase)  proteasome  protein degradation  ubiquitylation (ubiquitination)  NEDD4L  PIK3CA  LIGASE NEDD4L  C2 DOMAIN  T-CELLS  CBL-B  CANCER  EXPRESSION  MUTATIONS  DEGRADATION  PROGRESSION  PROGNOSIS   Loss of Dnmt3b accelerates MLL-AF9 leukemia progression 期刊论文 LEUKEMIA, 2016 Zheng, Y.; Zhang, H.; Wang, Y.; Li, X.; Lu, P.; Dong, F.; Pang, Y.; Ma, S.; Cheng, H.; Hao, S.; Tang, F.; Yuan, W.; Zhang, X.; Cheng, T. 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 ACUTE MYELOID-LEUKEMIA  HEMATOPOIETIC STEM-CELLS  GENE-EXPRESSION PROFILES  HEMATOLOGICAL MALIGNANCIES  DNA METHYLTRANSFERASE-1  POTENT INHIBITOR  CANCER  METHYLATION  TRANSFORMATION  MUTATIONS   A two-layer assay for single-nucleotide variants utilizing strand displacement and selective digestion 期刊论文 BIOSENSORS & BIOELECTRONICS, 2016 Yu, Yingjie; Wu, Tongbo; Johnson-Buck, Alexander; Li, Lidan; Su, Xin 收藏  |  浏览/下载：2/0  |  提交时间：2017/12/03 Single nucleotide variant  Toehold strand displacement  Lambda exonuclease  Fluorescent probe  DNA  HYBRIDIZATION  MUTATIONS  MEDICINE  PLASMA   Investigation on the formation, conversion and bioactivity of a G-quadruplex structure in the PALB2 gene 期刊论文 INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2016 Li, Fangyuan; Zhou, Jiang; Xu, Ming; Yuan, Gu 收藏  |  浏览/下载：5/0  |  提交时间：2017/12/03 PALB2 gene  G-quadruplex  ESI-MS  BREAST-CANCER  PROMOTER  MUTATIONS  LIGANDS  REGION  ASSAY  RECOGNITION  PROTEIN  REPAIR  BRCA2   A microscopic landscape of the invasive breast cancer genome 其他 2016-01-01 Ping, Zheng; Xia, Yuchao; Shen, Tiansheng; Parekh, Vishwas; Siegal, Gene P.; Eltoum, Isam-Eldin; He, Jianbo; Chen, Dongquan; Deng, Minghua; Xi, Ruibin; Shen, Dejun 收藏  |  浏览/下载：6/0  |  提交时间：2017/12/03 COMPREHENSIVE MOLECULAR PORTRAITS  CHRONIC LYMPHOCYTIC-LEUKEMIA  HISTOLOGIC GRADE  PIK3CA MUTATIONS  CLONAL EVOLUTION  GENE  STRATIFICATION  AMPLIFICATION  PROGNOSIS  SURVIVAL