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科研机构
上海药物研究所 [8]
复旦大学上海医学院 [4]
中国医学科学院 北京... [4]
山东大学 [3]
武汉大学 [3]
吉林大学白求恩第一医... [2]
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期刊论文 [37]
会议论文 [1]
发表日期
2014 [38]
学科主题
Hematology... [1]
biochemist... [1]
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发表日期:2014
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An in vivo and in vitro inhibitory action of natural oestrogen 17β-estradiol and environmental oestrogen 4-nonylphenol on eyestalks GIH expressions in Litopenaeus vannamei
会议论文
湛江, 2014-12-1
作者:
Guang-Li li
;
Hua-Pu Chen
;
Si-Ping Deng
;
Man Ye
;
Shuna Jiang
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/26
Litopenaeus
vannamei
gonad-inhibiting
hormone
feedback
regulation
oestrogen
estrogen
receptor
antagonist
Exploring details about structure requirements based on novel CGRP receptor antagonists urethanamide, aspartate, succinate and pyridine derivatives by in silico methods
期刊论文
journal of molecular structure, 2014, 卷号: 1074, 页码: 294-301
作者:
Li, Yan
;
He, Haoran
;
Wang, Jinghui
;
Han, Chunxiao
;
Feng, Jiaqi
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2015/11/17
Migraine
CGRP receptor antagonist
3D-QSAR
Molecular docking
The hypotensive effect of intrathecally injected (m) VD-hemopressin(alpha) in urethane-anesthetized rats
期刊论文
PEPTIDES, 2014, 卷号: 56, 页码: 45-51
作者:
Li, XH
;
Li, N
;
Wang, ZL
;
Pan, JX
;
Han, ZL
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/12/22
Cannabinoid
(m)VD-hemopressin(alpha)
Hypotensive response
Antagonist
Rat
The hit-to-lead optimization of 1,2,3,4,4a,9a-hexahydro-1H-xanthenes as glucocorticoid receptor antagonists
期刊论文
CHINESE CHEMICAL LETTERS, 2014, 卷号: 25, 期号: 5, 页码: 693-698
作者:
Zhu, Yan-Hui
;
Zhang, Meng
;
Li, Qun-Yi
;
Liu, Qing
;
Zhang, Jie
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
Glucocorticoid receptor
Antagonist
1,2,3,4,4a,9a-Hexahydroxanthene
Structure-activity relationship
Lead optimization
Development of beta-amino-carbonyl compounds as androgen receptor antagonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 5, 页码: 664-673
作者:
Zhang, Zhi-yun
;
Zhu, Yan-hui
;
Zhou, Cai-hong
;
Liu, Qing
;
Lu, Hui-li
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
prostate cancer
structural modification
androgen receptor
antagonist
molecular docking
beta-amino-carbonyl compound
Design, synthesis, biological evaluation, and comparative docking study of 1,2,4-triazolones as CB1 receptor selective antagonists
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 74, 页码: 73-84
作者:
Han, Shuang
;
Zhang, Fei-Fei
;
Xie, Xin
;
Chen, Jian-Zhong
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2019/01/08
Cannabinoid receptors
Antagonist
1,2,4-Triazolone
Scaffold hopping
Homology model
Discovery and SAR study of hydroxyacetophenone derivatives as potent, non-steroidal farnesoid X receptor (FXR) antagonists
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 5, 页码: 1596-1607
作者:
Liu, Peng
;
Xu, Xing
;
Chen, Lili
;
Ma, Lei
;
Shen, Xu
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2019/01/08
FXR antagonist
SAR study
Hydroxyacetophenone derivatives
Non-steroidal
A bufadienolide derived androgen receptor antagonist with inhibitory activities against prostate cancer cells
期刊论文
CHEMICO-BIOLOGICAL INTERACTIONS, 2014, 卷号: 207, 页码: 16-22
作者:
Tian, Hai-Yan
;
Yuan, Xiao-Feng
;
Jin, Lu
;
Li, Juan
;
Luo, Cheng
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
Androgen receptor
Antagonist
Bufadienolide
Molecular docking
Na+/K+ ATPase
Efficacy and Safety of Prolonged-Release Trazodone in Major Depressive Disorder: A Multicenter, Randomized, Double-Blind, Flexible-Dose Trial
期刊论文
PHARMACOLOGY, 2014, 卷号: 94, 期号: 5-6
作者:
Wang, Gang
;
Zhang, Lin
;
Xie, Wei-Wei
;
Li, Le-Hua
;
Zhang, Hong-Geng
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/04
Major depressive disorder
Trazodone
Serotonin-2 antagonist/reuptake inhibitor
Placebo-controlled trial
Hamilton Depression Rating Scale
Substance P receptor antagonist in lateral habenula improves rat depression-like behavior
期刊论文
BRAIN RESEARCH BULLETIN, 2014, 卷号: 100
作者:
Yang, Li-Min
;
Yu, Lei
;
Jin, Hui-Juan
;
Zhao, Hua
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/05
Lateral habenula
Depression-like behavior
Serotonin
Dorsal raphe nucleus
Substance P
Substance P receptor antagonist
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