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Metabolism of IMM-H004 and Its Pharmacokinetic-Pharmacodynamic Analysis in Cerebral Ischemia/Reperfusion Injured Rats 期刊论文
2019, 卷号: 10, 页码: 631
作者:  Zhang, Ziqian;  Liu, Dandan;  Jiang, Jianwei;  Song, Xiuyun;  Zou, Xiaowen
收藏  |  浏览/下载:16/0  |  提交时间:2020/01/03
IMM-H004 therapy for permanent focal ischemic cerebral injury via CKLF1/CCR4-mediated NLRP3 inflammasome activation 期刊论文
2019, 卷号: 212, 页码: 36-53
作者:  Ai Q D;  Chen Chen;  Chu Shifeng;  Zhang Zhao;  Luo Yun
收藏  |  浏览/下载:26/0  |  提交时间:2020/01/03
ASC = apoptosis-associated speck-like protein containing a caspase activation recruitment domain  BCA = bicinchoninic acid  BSA = bovine serum albumin  CCA = common carotid artery  CCR4 = C-C chemokine receptor type 4  CKLF1 = chemokine-like factor 1  CO-IP = coimmunoprecipitation  ECA = external carotid artery  ELISA = enzyme-linked immunosorbent assay  FDA = Food and Drug Administration  I/R = ischemic/reperfusion  ICA = internal carotid artery  IL-18 = interleukin 18  IL-1β = interleukin 1β  LDH = lactate dehydrogenase  NLRP3 = NOD-like receptor protein 3  PBS = phosphate-buffered saline  SD = standard deviation  TNF-α = tumor necrosis factor α  TTC = 2  3  5-triphenyltetrazolium-chloride  WT = wild-type  pMCAO = permanent middle cerebral artery occlusion  pro-Caspase-1 = precursor Caspase-1  qPCR = quantitative real-time PCR  tMCAO = transient middle cerebral artery occlusion  tPA = tissue plasminogen activator  
IMM-H004 Protects against Cerebral Ischemia Injury and Cardiopulmonary Complications via CKLF1 Mediated Inflammation Pathway in Adult and Aged Rats 期刊论文
2019, 卷号: 20, 期号: 7
作者:  Ai, Qidi;  Chen, Chen;  Chu, Shifeng;  Luo, Yun;  Zhang, Zhao
收藏  |  浏览/下载:7/0  |  提交时间:2020/01/03
A20 as a novel target for the anti-neuroinflammatory effect of chrysin via inhibition of NF-kappa B signaling pathway 期刊论文
2019, 卷号: 79, 页码: 228-235
作者:  Li, Zhipeng;  Chu, Shifeng;  He, Wenbin;  Zhang, Zhao;  Liu, Jiaqi
收藏  |  浏览/下载:2/0  |  提交时间:2020/01/03
IMM-H004 protects against oxygen-glucose deprivation/reperfusion injury to BV2 microglia partly by modulating CKLF1 involved in microglia polarization 期刊论文
2019, 卷号: 70, 页码: 69-79
作者:  Chen, Chen;  Ai, Qidi;  Chu, Shifeng;  Zhang, Zhao;  Zhou, Xin
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/03
Pyrano[3,2-a]carbazole alkaloids as effective agents against ischemic stroke in vitro and in vivo 期刊论文
2018, 卷号: 143, 页码: 438-448
作者:  Zang, Yingda;  Song, Xiuyun;  Li, Chuangjun;  Ma, Jie;  Chu, Shifeng
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03
Antioxidant activities of ginsenoside Rg1 against cisplatin-induced hepatic injury through Nrf2 signaling pathway in mice 期刊论文
2017, 卷号: 51, 期号: 1, 页码: 1-13
作者:  Gao, Yan;  Chu, Shifeng;  Shao, Qianhang;  Zhang, Meijin;  Xia, Congyuan
收藏  |  浏览/下载:5/0  |  提交时间:2020/01/03
Possible target-related proteins of stress-resistant rats suggested by label-free proteomic analysis 期刊论文
2017, 卷号: 7, 期号: 65, 页码: 40957-40964
作者:  Chen, Jiao;  Wang, Zhenzhen;  Zhang, Shuai;  Ai, Qidi;  Chu, Shifeng
收藏  |  浏览/下载:6/0  |  提交时间:2020/01/04
Nootropic effect and action mechanisms of Ginsenoside Rg1, a smart drug candidate 期刊论文
2017, 卷号: 139, 期号: ,SI, 页码: 108-109
作者:  Zhang, Juntian;  Chu, Shifeng
收藏  |  浏览/下载:3/0  |  提交时间:2020/01/04
Nootropic effect and action mechanisms of Ginsenoside Rg1, a smart drug candidate 会议论文
BIOCHEMICAL PHARMACOLOGY, 2017-09-01
作者:  Zhang, Juntian;  Chu, Shifeng
收藏  |  浏览/下载:4/0  |  提交时间:2020/01/03


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