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中国医学科学院 北... [45]
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期刊论文 [45]
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2019 [5]
2018 [11]
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专题:中国医学科学院 北京协和医学院
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Clinical and genetic analysis in a large Chinese cohort of patients with X-linked hypophosphatemia
期刊论文
2019, 卷号: 121, 页码: 212-220
作者:
Zhang, Cong
;
Zhao, Zhen
;
Sun, Yue
;
Xu, Lijun
;
JiaJue, Ruizhi
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/01/03
X-linked hypophosphatemia (XLH)
PHEX
Genetic analysis
Sex difference
Genotype-phenotype correlation
3D model of PHEX
Glutaredoxin 1 up-regulates deglutathionylation of alpha 4 integrin and thereby restricts neutrophil mobilization from bone marrow
期刊论文
2019, 卷号: 294, 期号: 8, 页码: 2616-2627
作者:
You, Yuanyuan
;
Chen, Junli
;
Zhu, Feimei
;
Xu, Qian
;
Han, Lu
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2020/01/03
glutathionylation
reactive oxygen species (ROS)
integrin
neutrophil
inflammation
alpha 4 integrin
glutaredoxin
immune response
neutrophil mobilization
vascular cell adhesion molecular 1 (VCAM-1)
Efficacy and safety of ranibizumab 0.5 mg in Chinese patients with visual impairment due to diabetic macular edema: results from the 12-month REFINE study
期刊论文
2019, 卷号: 257, 期号: 3, 页码: 529-541
作者:
Li, Xiaoxin
;
Dai, Hong
;
Li, Xiaorong
;
Han, Mei
;
Li, Jun
收藏
  |  
浏览/下载:172/0
  |  
提交时间:2020/01/03
Anti-vascular endothelial growth factor
Diabetic macular edema
Pro re nata
Ranibizumab
Structure-based modification of carbonyl-diphenylpyrimidines (Car-DPPYs) as a novel focal adhesion kinase (FAK) inhibitor against various stubborn cancer cells
期刊论文
2019, 卷号: 172, 页码: 154-162
作者:
Wang, Luhong
;
Ai, Min
;
Yu, Jiawen
;
Jin, Lingling
;
Wang, Changyuan
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Cancer
FAK
Inhibitor
Pyrimidine
Activity
Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
期刊论文
2019, 卷号: 567, 期号: 7747, 页码: 257-+
作者:
Jiang, Ying
;
Sun, Aihua
;
Zhao, Yang
;
Ying, Wantao
;
Sun, Huichuan
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2020/01/03
Novel amino acid-substituted diphenylpyrimidine derivatives as potent BTK inhibitors against B cell lymphoma cell lines
期刊论文
2018, 卷号: 26, 期号: 14, 页码: 4179-4186
作者:
Wang, Changyuan
;
Li, Si
;
Meng, Qiang
;
Sun, Xiuli
;
Li, Hua
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/01/03
Structural optimization of diphenylpyrimidine scaffold as potent and selective epidermal growth factor receptor inhibitors against L858R/T790M resistance mutation in nonsmall cell lung cancer
期刊论文
2018, 卷号: 92, 期号: 6, 页码: 1988-1997
作者:
Yi, Yuanyuan
;
Wang, Luhong
;
Zhao, Dan
;
Huang, Shanshan
;
Wang, Changyuan
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
EGFR T790M
inhibitors
NSCLC
pyrimidine
resistance
In Silico Prediction of O-6-Methylguanine-DNA Methyltransferase Inhibitory Potency of Base Analogs with QSAR and Machine Learning Methods
期刊论文
2018, 卷号: 23, 期号: 11
作者:
Sun, Guohui
;
Fan, Tengjiao
;
Sun, Xiaodong
;
Hao, Yuxing
;
Cui, Xin
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2020/01/03
MGMT
anticancer alkylating agents
resistance
inhibitors
QSAR
classification
Hepatoprotective effect of rhein against methotrexate-induced liver toxicity
期刊论文
2018, 卷号: 834, 页码: 266-273
作者:
Bu, Tianci
;
Wang, Changyuan
;
Meng, Qiang
;
Huo, Xiaokui
;
Sun, Huijun
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Methotrexate
Diacerein
Rhein
Hepatotoxicity
Nuclear factor erythroid 2-related factor 2
Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Neurocysticercosis
期刊论文
2018, 卷号: 9, 页码: 471
作者:
Fan, Siyuan
;
Qiao, Xiaodong
;
Liu, Lei
;
Wu, Honglong
;
Zhou, Jiali
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/01/03
neurocysticercosis
Taenia solium
cerebrospinal fluid
next-generation sequencing
reads
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