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CORC

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Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 4, 页码: 2083-2098
作者:  Huang, Boshi;  Chen, Wenmin;  Zhao, Tong;  Li, Zhenyu;  Jiang, Xiangyi
收藏  |  浏览/下载：15/0  |  提交时间：2019/12/11
Mechanistic effect of the human GJB6 gene and its mutations in HaCaT cell proliferation and apoptosis 期刊论文
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2018, 卷号: 51, 期号: 9
作者:  Lu, Yuting;  Zhang, Ruili;  Wang, Zhenying;  Zhou, Shuhua;  Song, Yali
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/11
Structural optimization of pyridine-type DAPY derivatives to exploit the tolerant regions of the NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 121, 页码: 352-363
作者:  Chen, Wenmin;  Zhan, Peng;  Daelemans, Dirk;  Yang, Jiapei;  Huang, Boshi
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/16
Design, synthesis and anti-HIV evaluation of novel diarylpyridine derivatives targeting the entrance channel of NNRTI binding pocket 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 卷号: 109, 页码: 294-304
作者:  Yang, Jiapei;  Chen, Wenmin;  Kang, Dongwei;  Lu, Xueyi;  Li, Xiao
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches 期刊论文
European Journal of Medicinal Chemistry: Chimie Therapeutique, 2015, 页码: 754-765
作者:  Huang, Boshi;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao;  Yu, Mingyan
收藏  |  浏览/下载：6/0  |  提交时间：2019/12/17
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 754-765
作者:  Huang, Boshi;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao;  Yu, Mingyan
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: Design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 93, 页码: 330-337
作者:  Huang, Boshi;  Liang, Xin;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao
收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: Design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines 期刊论文
European Journal of Medicinal Chemistry: Chimie Therapeutique, 2015, 页码: 330-337
作者:  Huang, Boshi;  Liang, Xin;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17
Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 2: Discovery of novel [1,2,4]Triazolo[1,5-a]pyrimidines using a structure-guided core-refining approach 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2014, 卷号: 85, 页码: 293-303
作者:  Wang, Liu;  Tian, Ye;  Chen, Wenmin;  Liu, Hong;  Zhan, Peng
收藏  |  浏览/下载：4/0  |  提交时间：2019/12/17
Synthesis and Anti-HIV Activity of 4-(Naphthalen-1-yl)- 1,2,5-thiadiazol-3-hydroxyl Derivatives 期刊论文
Chemical biology and drug design, 2014, 卷号: 84, 期号: 4, 页码: 420-430
作者:  Diwakar Rai;  Wenmin Chen;  Peng Zhan;  Hong Liu;  Ye Tian
收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17

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