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浏览/检索结果: 共12条，第1-10条 帮助 限定条件 专题：山东大学    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Design, synthesis and biological evaluation of tacrine-1,2,3-triazole derivatives as potent cholinesterase inhibitors 期刊论文 MEDCHEMCOMM, 2018, 卷号: 9, 期号: 1, 页码: 149-159 作者:  Wu, Gaochan;  Gao, Yun;  Kang, Dongwei;  Huang, Boshi;  Huo, Zhipeng 收藏  |  浏览/下载：7/0  |  提交时间：2019/12/11 Discovery of novel piperidine-substituted indolylarylsulfones as potent HIV NNRTIs via structure-guided scaffold morphing and fragment rearrangement 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 126, 页码: 190-201 作者:  Li, Xiao;  Gao, Ping;  Huang, Boshi;  Zhou, Zhongxia;  Yu, Zhao 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/11 HIV  NNRTIs  Indolylarylsulfones  Antiviral activity  SAR  Molecular  modeling  Chemical space  Drug design   Discovery of novel DAPY-IAS hybrid derivatives as potential HIV-1 inhibitors using molecular hybridization based on crystallographic overlays 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY, 2017, 卷号: 25, 期号: 16, 页码: 4397-4406 作者:  Huang, Boshi;  Wang, Xueshun;  Liu, Xinhao;  Chen, Zihui;  Li, Wanzhuo 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/11 HIV-1 inhibitors  DAPY-IAS hybrids  Crystallographic overlays  Drug  design  SARs  Molecular modeling   Facile TEMPO Immobilization onto Poly(acrylic acid)-Modified Magnetic Nanoparticles: Preparation and Property 期刊论文 INTERNATIONAL JOURNAL OF POLYMER SCIENCE, 2017 作者:  Huang, Guohui;  Liu, Xiaoxuan;  Bei, Yiling;  Ma, Huiqing 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/12 Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches 期刊论文 European Journal of Medicinal Chemistry: Chimie Therapeutique, 2015, 页码: 754-765 作者:  Huang, Boshi;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao;  Yu, Mingyan 收藏  |  浏览/下载：6/0  |  提交时间：2019/12/17 Triazolopyrimidines  Structure-based drug design  Biological activity  HIV-1 RT  Physicochemical properties  Molecular simulations   Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 3: Optimization of [1,2,4]triazolo[1,5-a]pyrimidine core via structure-based and physicochemical property-driven approaches 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 92, 页码: 754-765 作者:  Huang, Boshi;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao;  Yu, Mingyan 收藏  |  浏览/下载：3/0  |  提交时间：2019/12/17 Triazolopyrimidines  Structure-based drug design  Biological activity  HIV-1 RT  Physicochemical properties  Molecular simulations   Fused heterocycles bearing bridgehead nitrogen as potent HIV-1 NNRTIs. Part 4: Design, synthesis and biological evaluation of novel imidazo[1,2-a]pyrazines 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 93, 页码: 330-337 作者:  Huang, Boshi;  Liang, Xin;  Li, Cuicui;  Chen, Wenmin;  Liu, Tao 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17 HIV-1 RT  Imidazo[1,2-a]pyrazines  Core-refining  NNRTIs  Biological  activity  Molecular simulation   Design, Synthesis, and Biological Evaluation of Novel 4-Aminopiperidinyl-linked 3,5-Disubstituted-1,2,6-thiadiazine-1,1-dione Derivatives as HIV-1 NNRTIs 期刊论文 Chemical biology and drug design, 2015, 卷号: 86, 期号: 1, 页码: 887-893 作者:  Liu, Tao;  Huang, Boshi;  Tian, Ye;  Liang, Xin;  Liu, Hong 收藏  |  浏览/下载：9/0  |  提交时间：2019/12/17 1  2  6-thiadiazine-1  1-dione  bioactivity  drug design  HIV-1  NNRTIs  RT  synthesis   Synthesis and Preliminary Antiviral Activities of Piperidine-substituted Purines against HIV and Influenza A/H1N1 Infections 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 568-577 作者:  Kang, Dongwei;  Fang, Zengjun;  Huang, Boshi;  Zhang, Lingzi;  Liu, Huiqing 收藏  |  浏览/下载：2/0  |  提交时间：2019/12/17 bioactivity  heterocycle  HIV  influenza virus  NNRTIs  structure-activity relationship  synthesis   Synthesis and Biological Evaluation of a Series of 2-((1-substituted-1H-1,2,3-triazol-4-yl)methylthio)-6-(naphthalen-1-ylme thyl)pyrimidin-4(3H)-one As Potential HIV-1 Inhibitors 期刊论文 CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 614-618 作者:  Fang, Zengjun;  Kang, Dongwei;  Zhang, Lingzi;  Huang, Boshi;  Liu, Huiqing 收藏  |  浏览/下载：5/0  |  提交时间：2019/12/17 antiviral activity  click chemistry  drug design  HIV  NNRTIs  pyrimidine  SAR