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科研机构
海洋研究所 [55]
内容类型
期刊论文 [55]
发表日期
2023 [1]
2021 [2]
2020 [7]
2019 [14]
2018 [7]
2017 [3]
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Oceanograp... [7]
Limnology [3]
Marine & F... [3]
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Silk fibroin peptide self-assembled nanofibers delivered naringenin to alleviate cisplatin-induced acute kidney injury by inhibiting mtDNA-cGAS-STING pathway
期刊论文
FOOD AND CHEMICAL TOXICOLOGY, 2023, 卷号: 177, 页码: 10
作者:
Liu, Shuai
;
Gao, Xintao
;
Yin, Yulan
;
Wang, Jing
;
Dong, Kehong
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/13
Silk fibroin peptide
Naringin
Acute kidney injury
Mitophagy
cGAS-STING pathway
Palladium-Catalyzed Remote C-H Phosphonylation of Indoles at the C4 and C6 Positions by a Radical Approach
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Shi, Xiaolin
;
Wang, Zemin
;
Li, Yuxiu
;
Li, Xiaowei
;
Li, Xiangqian
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2021/06/04
C−
H activation
indoles
palladium
phosphonylation
regioselectivity
The Involvement of the Mammalian Target of Rapamycin, Protein Tyrosine Phosphatase 1b and Dipeptidase 4 Signaling Pathways in Cancer and Diabetes: A Narrative Review
期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2021, 卷号: 21, 期号: 7, 页码: 803-815
作者:
Zhang, Jiajia
;
Wu, Ning
;
Shi, Dayong
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2021/05/11
Signaling pathway
mammalian target of rapamycin
protein tyrosine phosphatase 1b
dipeptidase 4
cancer
diabetes
pharmacology
target compounds
Antidiabetic activity in vitro and in vivo of BDB, a selective inhibitor of protein tyrosine phosphatase 1B, fromRhodomela confervoides
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2020, 卷号: 177, 期号: 19, 页码: 4464-4480
作者:
Luo, Jiao
;
Zheng, Meiling
;
Jiang, Bo
;
Li, Chao
;
Guo, Shuju
收藏
  |  
浏览/下载:136/0
  |  
提交时间:2020/09/29
bromophenol
PTP1B inhibitor
selectivity
cell permeability
oral bioavailability
AcOH-mediated aerobic oxidative synthesis of 2-thioalkylbenzothiazoles via a three-component reaction
期刊论文
TETRAHEDRON LETTERS, 2020, 卷号: 61, 期号: 26, 页码: 5
作者:
Li, Xiaowei
;
Li, Yuxiu
;
Liu, Ruihua
;
Wang, Zemin
;
Li, Xiangqian
收藏
  |  
浏览/下载:109/0
  |  
提交时间:2020/09/25
2-Thioalkylbenzothiazoles
Metal-free
Aerobic oxidation
Multicomponent reaction
BTH-8, a novel poly (ADP-ribose) polymerase-1 (PARP-1) inhibitor, causes DNA double-strand breaks and exhibits anticancer activities in vitro and in vivo
期刊论文
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2020, 卷号: 150, 页码: 238-245
作者:
Guo, Chuanlong
;
Zhang, Fan
;
Wu, Xiaochen
;
Yu, Xuemin
;
Wu, Xianggen
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/09/23
PARP-1 inhibitor
DNA double-strand breaks
HCC-1937
In vivo
Apoptosis
CYC31, A Natural Bromophenol PTP1B Inhibitor, Activates Insulin Signaling and Improves Long Chain-Fatty Acid Oxidation in C2C12 Myotubes
期刊论文
MARINE DRUGS, 2020, 卷号: 18, 期号: 5, 页码: 13
作者:
Luo, Jiao
;
Hou, Yufei
;
Xie, Mengyue
;
Ma, Wanli
;
Shi, Dayong
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/09/25
CYC31
PTP1B inhibitor
insulin resistance
fatty acid oxidization
An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study
期刊论文
JOURNAL OF ANALYTICAL SCIENCE AND TECHNOLOGY, 2020, 卷号: 11, 期号: 1, 页码: 7
作者:
Li, Xiuxue
;
Wang, Lijun
;
Jia, Xiaoling
;
Guo, Chuanlong
;
Li, Chao
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/09/23
Novel compound
Quantitation
UHPLC-TOF-MS
Pharmacokinetics
The Fluoro-Thiazolylhydrazone Compound TSC-3C Inhibits Triple Negative Breast Cancer (TNBC) Cell Line Activity by Promoting Apoptosis, Regulating the MAPK Pathway and Inducing Mitochondrial Dysfunction
期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 3, 页码: 15
作者:
Zhang, Jiajia
;
Dai, Jiajia
;
Zheng, Qingxuan
;
Guo, Shuju
;
Yu, Yanyan
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/09/23
triple negative breast cancer
MDA-MB-231 cells
fluoro-thiazolylhydrazone
MAPK pathway
phosphorylated p44/42 MAPK (ERK1/2)
phosphorylated c-Jun N-terminal kinase (p-JNK)
apoptosis
Structural and Bioactive Studies of Halogenated Constituents from Sponges
期刊论文
CURRENT MEDICINAL CHEMISTRY, 2020, 卷号: 27, 期号: 14, 页码: 2335-2360
作者:
Li, Chao
;
Shi, Dayong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/09/24
Halogenated
sponges
marine
isolate
constitutes
activity
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