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CORC

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Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 11
作者:  Fan, Shijie;  Yue, Liyan;  Wan, Wei;  Zhang, Yuanyuan;  Zhang, Bidong
收藏  |  浏览/下载：80/0  |  提交时间：2021/12/16
Discovery of chiral N-2 '-aryletheryl-1 '-alkoxy-ethyl substituted arylisoquinolones with anti-inflammatory activity from the nucleophilic addition reactions of the thiophenols and oxazolinium 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 222, 页码: 11
作者:  Li, Bo;  Li, Heng;  Zhu, Zhengdan;  Xiang, Caigui;  Xu, Zhijian
收藏  |  浏览/下载：99/0  |  提交时间：2021/11/04
S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis 期刊论文
CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY, 2021, 卷号: 11, 期号: 3, 页码: 697-724
作者:  Zhang, Linqiang;  Zhang, Zhiguo;  Li, Chengbin;  Zhu, Tingting;  Gao, Jing
收藏  |  浏览/下载：49/0  |  提交时间：2021/05/24
A Phase I Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of TPN171H, a Novel Phosphodiesterase Type 5 Inhibitor, in Healthy Subjects 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15, 页码: 2947-2959
作者:  Qian, Hongjie;  Chen, Qian;  Lang, Liyu;  Zou, Yang;  Pu, Huahua
收藏  |  浏览/下载：35/0  |  提交时间：2021/08/17
Exploring the protective effects of Danqi Tongmai tablet on acute myocardial ischemia rats by comprehensive metabolomics profiling 期刊论文
PHYTOMEDICINE, 2020, 卷号: 74, 页码: 9
作者:  Li Zhenwei;  Hou Jinjun;  Deng Yanping;  Zhi Haijuan;  Wu Wenyong
收藏  |  浏览/下载：27/0  |  提交时间：2020/12/24
Accurate prediction of relative binding affinities of a series of HIV-1 protease inhibitors using semi-empirical quantum mechanical charge 期刊论文
JOURNAL OF COMPUTATIONAL CHEMISTRY, 2020, 页码: 8
作者:  Peng, Cheng;  Wang, Jinan;  Xu, Zhijian;  Cai, Tingting;  Zhu, Weiliang
收藏  |  浏览/下载：24/0  |  提交时间：2020/07/01
Exploring Conformational Change of Adenylate Kinase by Replica Exchange Molecular Dynamic Simulation 期刊论文
BIOPHYSICAL JOURNAL, 2020, 卷号: 118, 期号: 5, 页码: 1009-1018
作者:  Wang, Jinan;  Peng, Cheng;  Yu, Yuqu;  Chen, Zhaoqiang;  Xu, Zhijian
收藏  |  浏览/下载：42/0  |  提交时间：2020/07/01
Allosteric Regulation of Hsp90 alpha's Activity by Small Molecules Targeting the Middle Domain of the Chaperone 期刊论文
ISCIENCE, 2020, 卷号: 23, 期号: 2, 页码: 46
作者:  Zhou, Chen;  Zhang, Chi;  Zhu, Hongwen;  Liu, Zhijun;  Su, Haixia
收藏  |  浏览/下载：145/0  |  提交时间：2020/07/01
Selective activation of TWIK-related acid-sensitive K+ 3 subunit-containing channels is analgesic in rodent models 期刊论文
SCIENCE TRANSLATIONAL MEDICINE, 2019, 卷号: 11, 期号: 519, 页码: 12
作者:  Liao, Ping;  Qiu, Yunguang;  Mo, Yiqing;  Fu, Jie;  Song, Zhenpeng
收藏  |  浏览/下载：31/0  |  提交时间：2020/07/01
Improving the accuracy of predicting protein-ligand binding-free energy with semiempirical quantum chemistry charge 期刊论文
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 4, 页码: 303-321
作者:  Peng, Cheng;  Wang, Jinan;  Yu, Yuqi;  Wang, Guimin;  Chen, Zhaoqiang
收藏  |  浏览/下载：3/0  |  提交时间：2020/07/01

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