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Discovery of an M-Substituted N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaine as a Selective, Potent, and Orally Active kappa-Opioid Receptor Agonist with an Improved Central Nervous System Safety Profile 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12414-12433
作者:  He, Qian;  Wei, Yuanyuan;  Liu, Xiao;  Ye, Rongrong;  Kong, Linghui
收藏  |  浏览/下载:88/0  |  提交时间:2021/11/04
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:  Wang, Lin;  Wu, Yan;  Yao, Sheng;  Ge, Huan;  Zhu, Ya
收藏  |  浏览/下载:86/0  |  提交时间:2021/11/04
Neolinulicin A and B from Inula japonica and their anti-inflammatory activities 期刊论文
FITOTERAPIA, 2021, 卷号: 152, 页码: 6
作者:  Wu, Rui-fang;  Zhou, Bing-duo;  Wang, Wen-qiong;  Chen, Tong;  Xu, Ting-ting
收藏  |  浏览/下载:17/0  |  提交时间:2021/08/17
Anti-inflammatory sesquiterpene dimers and diterpenes from the aerial part of Inula japonica 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2021, 页码: 8
作者:  Wu, Rui-Fang;  Wang, Wen-Qiong;  Zhou, Bing-Duo;  Wang, Yi;  Li, Ya-Ding
收藏  |  浏览/下载:37/0  |  提交时间:2021/08/17
Exploration of the SAR Connection between Morphinan- and Arylacetamide-Based kappa Opioid Receptor (kappa OR) Agonists Using the Strategy of Bridging 期刊论文
ACS CHEMICAL NEUROSCIENCE, 2021, 卷号: 12, 期号: 6, 页码: 1018-1030
作者:  Liu, Xiao;  Jiang, Shuang;  Kong, Linghui;  Ye, Rongrong;  Xiao, Li
收藏  |  浏览/下载:114/0  |  提交时间:2021/05/24
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan
收藏  |  浏览/下载:85/0  |  提交时间:2020/12/24
Teratopyrones A-C, Dimeric Naphtho-gamma-Pyrones and Other Metabolites from Teratosphaeria sp. AK1128, a Fungal Endophyte of Equisetum arvense 期刊论文
MOLECULES, 2020, 卷号: 25, 期号: 21, 页码: 10
作者:  Xu, Ya-Ming;  Arnold, A. Elizabeth;  U'Ren, Jana M.;  Xuan, Li-Jiang;  Wang, Wen-Qiong
收藏  |  浏览/下载:19/0  |  提交时间:2020/12/24
Three new dibenzofurans from Cydonia oblonga Mill 期刊论文
NATURAL PRODUCT RESEARCH, 2020, 卷号: 34, 期号: 8, 页码: 1146-1151
作者:  Wei, Jiao-Jiao;  Wang, Wen-Qiong;  Song, Wei-Bin
收藏  |  浏览/下载:37/0  |  提交时间:2020/07/01
23,24-Dihydrocucurbitacin B promotes lipid clearance by dual transcriptional regulation of LDLR and PCSK9 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 327-335
作者:  Li, Hui-hui;  Li, Jun;  Zhang, Xian-jing;  Li, Jiao-meng;  Xi, Cong
收藏  |  浏览/下载:24/0  |  提交时间:2020/07/01
Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 24, 页码: 11054-11070
作者:  Xiao, Li;  Wang, Yujun;  Zhang, Mumei;  Wu, Weiwei;  Kong, Linghui
收藏  |  浏览/下载:92/0  |  提交时间:2020/07/01


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