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科研机构
北京大学 [20]
内容类型
期刊论文 [16]
其他 [4]
发表日期
2017 [3]
2015 [1]
2014 [2]
2013 [2]
2012 [4]
2011 [4]
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专题:北京大学
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Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State
期刊论文
CELL STEM CELL, 2017
Li, Xiang
;
Liu, Defang
;
Ma, Yantao
;
Du, Xiaomin
;
Jing, Junzhan
;
Wang, Lipeng
;
Xie, Bingqing
;
Sun, Da
;
Sun, Shaoqiang
;
Jin, Xueqin
;
Zhang, Xu
;
Zhao, Ting
;
Guan, Jingyang
;
Yi, Zexuan
;
Lai, Weifeng
;
Zheng, Ping
;
Huang, Zhuo
;
Chang, Yanzhong
;
Chai, Zhen
;
Xu, Jun
;
Deng, Hongkui
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2017/12/03
PLURIPOTENT STEM-CELLS
SMALL-MOLECULE COMPOUNDS
FUNCTIONAL-NEURONS
DIRECT CONVERSION
PURKINJE NEURONS
SOMATIC-CELLS
HUMAN ES
FUSION
HEPATOCYTES
DISEASE
Brain-derived neurotrophic factor/neurotrophin 3 regulate axon initial segment location and affect neuronal excitability in cultured hippocampal neurons
期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017
Guo, Yu
;
Su, Zi-jun
;
Chen, Yi-kun
;
Chai, Zhen
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
axon initial segment
BDNF
hippocampal neuron
neuronal excitability
neuroplasticity
neurotrophins
ACTIVITY-DEPENDENT RELOCATION
ACTION-POTENTIAL GENERATION
STRUCTURAL PLASTICITY
CHANNELS
BDNF
TRANSPORT
MAINTENANCE
MODULATION
MECHANISMS
ANKYRIN(G)
Cyclodextrin-gated mesoporous silica nanoparticles as drug carriers for red light-induced drug release
期刊论文
NANOTECHNOLOGY, 2017
Chai, Shiqiang
;
Guo, Yu
;
Zhang, Zhenyu
;
Chai, Zhen
;
Ma, Yurong
;
Qi, Limin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
mesoporous silica nanoparticles
photodynamic therapy
drug delivery
cyclodextrin
UP-CONVERSION NANOPARTICLES
PHOTODYNAMIC THERAPY
UPCONVERTING NANOPARTICLES
LANTHANIDE NANOPARTICLES
CANCER-CELLS
DELIVERY
NANOCARRIERS
DESIGN
NANOCONTAINERS
THERANOSTICS
Small-Molecule-Driven Direct Reprogramming of Mouse Fibroblasts into Functional Neurons
期刊论文
CELL STEM CELL, 2015
Li, Xiang
;
Zuo, Xiaohan
;
Jing, Junzhan
;
Ma, Yantao
;
Wang, Jiaming
;
Liu, Defang
;
Zhu, Jialiang
;
Du, Xiaomin
;
Xiong, Liang
;
Du, Yuanyuan
;
Xu, Jun
;
Xiao, Xiong
;
Wang, Jinlin
;
Chai, Zhen
;
Zhao, Yang
;
Deng, Hongkui
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
DOPAMINERGIC-NEURONS
CELL FATE
CONVERSION
PLURIPOTENCY
IDENTIFICATION
EXPRESSION
GENERATION
INHIBITORS
GENES
Increased Na+/Ca2+ Exchanger Activity Promotes Resistance to Excitotoxicity in Cortical Neurons of the Ground Squirrel (a Hibernator)
期刊论文
plos one, 2014
Zhao, Juan-Juan
;
Gao, Shan
;
Jing, Jun-Zhan
;
Zhu, Ming-Yue
;
Zhou, Chen
;
Chai, Zhen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
OXYGEN-GLUCOSE DEPRIVATION
NMDA RECEPTOR ACTIVATION
OPERATED CA2+ ENTRY
METHYL-D-ASPARTATE
HIPPOCAMPAL-NEURONS
GLUTAMATE EXCITOTOXICITY
CALCIUM NEUROTOXICITY
INTRACELLULAR CA2+
NADPH OXIDASE
CELL-DEATH
ERp57 modulates mitochondrial calcium uptake through the MCU
期刊论文
欧洲生化学会联合会快报, 2014
He, Jingquan
;
Shi, Weikang
;
Guo, Yu
;
Chai, Zhen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2015/11/10
ERp57
MCU
Mitochondrial calcium uptake
CA2+ UPTAKE
CELL-DEATH
UNIPORTER
PROTEIN
MICU1
ACTIVATION
APOPTOSIS
CHAPERONE
INJURY
The propagation of astrocytic Ca~(2+) waves regulates the activation of extrasynaptic NMDA receptors in hippocampal neurons during ischemia and aggravates brain damage
其他
2013-01-01
Qiping DONG
;
Jingquan HE
;
Zhen CHAI
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2017/12/03
ischemia
calcium waves
gap junction
IP3R2
ischemia
calcium waves
gap junction
IP3R2
Astrocytic Ca2+ waves mediate activation of extrasynaptic NMDA receptors in hippocampal neurons to aggravate brain damage during ischemia
期刊论文
疾病神经生物学实验神经学b辑, 2013
Dong, Qi-ping
;
He, Jing-quan
;
Chai, Zhen
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2015/11/10
Ischemia
Extrasynaptic NMDA receptor
Astrocytic Ca2+ wave
Gap junction
CALCIUM WAVES
GLUTAMATE RELEASE
CELL-DEATH
IN-VITRO
PROPAGATION
MICE
EXCITOTOXICITY
PLASTICITY
CONTRIBUTE
EPILEPSY
Interleukin-1β inhibits the current of large conductance calciumactivated potassium channels and shapes the action potential in cortical neurons
其他
2012-01-01
Chen Zhou
;
Weiwei Zhang
;
Chaofei Bao
;
Liyao Zhang
;
Zhen Chai
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2017/12/03
IL-1β
BK channel
action potential
IL-1β
BK channel
action potential
Calcium activity of the astrocytic network contributes to the activation of exnmdars in rat neurons during ischemia
其他
2012-01-01
Qiping Dong
;
Jingquan He
;
Zhen Chai
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2017/12/03
astrocytic calcium
ischemia
extrasynaptic NMDA receptor
gap junction
astrocytic calcium
ischemia
extrasynaptic NMDA receptor
gap junction
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