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浏览/检索结果: 共14条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9 作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu 收藏  |  浏览/下载：39/0  |  提交时间：2022/01/04 phosphoinositide 3-kinase (PI3K)  activation  inhibition  activity-dependent conformational changes   Constitutive signal bias mediated by the human GHRHR splice variant 1 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 40, 页码: 10 作者:  Cong, Zhaotong;  Zhou, Fulai;  Zhang, Chao;  Zou, Xinyu;  Zhang, Huibing 收藏  |  浏览/下载：26/0  |  提交时间：2021/12/01 class B1 GPCR  receptor bias  cancer  cell proliferation   Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy 期刊论文 ORGANIC LETTERS, 2021, 卷号: 23, 期号: 19, 页码: 7381-7385 作者:  Lin, Bizhen;  Lu, Weiwei;  Chen, Zhen-yu;  Zhang, Yue;  Duan, Yin-zhe 收藏  |  浏览/下载：13/0  |  提交时间：2021/12/01 Structural insights into ligand recognition and activation of the melanocortin-4 receptor 期刊论文 CELL RESEARCH, 2021, 页码: 13 作者:  Zhang, Huibing;  Chen, Li-Nan;  Yang, Dehua;  Mao, Chunyou;  Shen, Qingya 收藏  |  浏览/下载：33/0  |  提交时间：2021/11/04 Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Huang, He-ming;  Fan, Shi-jie;  Zhou, Xiao-ru;  Liu, Yan-jun;  Li, Xiao 收藏  |  浏览/下载：58/0  |  提交时间：2021/11/04 nonalcoholic steatohepatitis  inflammation  histone deacetylase inhibitor  givinostat  epigenetics   Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng 收藏  |  浏览/下载：92/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   Structural insights into hormone recognition by the human glucose-dependent insulinotropic polypeptide receptor 期刊论文 ELIFE, 2021, 卷号: 10, 页码: 20 作者:  Zhao, Fenghui;  Zhang, Chao;  Zhou, Qingtong;  Hang, Kaini;  Zou, Xinyu 收藏  |  浏览/下载：36/0  |  提交时间：2021/08/17 GPR160 is a potential biomarker associated with prostate cancer 期刊论文 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 3 作者:  Guo, Wanjing;  Zhang, Junyu;  Zhou, Yan;  Zhou, Caihong;  Yang, Yunjie 收藏  |  浏览/下载：16/0  |  提交时间：2021/08/17 Molecular insights into ago-allosteric modulation of the human glucagon-like peptide-1 receptor 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 11 作者:  Cong, Zhaotong;  Chen, Li-Nan;  Ma, Honglei;  Zhou, Qingtong;  Zou, Xinyu 收藏  |  浏览/下载：45/0  |  提交时间：2021/08/17 SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target 期刊论文 CELL RESEARCH, 2021, 页码: 14 作者:  Xia, Bingqing;  Shen, Xurui;  He, Yang;  Pan, Xiaoyan;  Liu, Feng-Liang 收藏  |  浏览/下载：78/0  |  提交时间：2021/08/17