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浏览/检索结果: 共169条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters 期刊论文 CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256 作者:  Dong, Lei;  Zhang, Min-Yu;  Han, Hai-Hao;  Zang, Yi;  Chen, Guo-Rong 收藏  |  浏览/下载：30/0  |  提交时间：2022/01/18 LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang 收藏  |  浏览/下载：62/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   The methyltransferase METTL3 negatively regulates nonalcoholic steatohepatitis (NASH) progression 期刊论文 NATURE COMMUNICATIONS, 2021, 卷号: 12, 期号: 1, 页码: 17 作者:  Li, Xinzhi;  Yuan, Bingchuan;  Lu, Min;  Wang, Yuqin;  Ding, Na 收藏  |  浏览/下载：37/0  |  提交时间：2022/01/18 Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1 期刊论文 PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14 作者:  Zhang, Chun;  Sun, Yi-Tao;  Gao, Li-Xin;  Feng, Bo;  Yan, Xue 收藏  |  浏览/下载：19/0  |  提交时间：2022/01/18 Advancing COVID-19 diagnosis with privacy-preserving collaboration in artificial intelligence 期刊论文 NATURE MACHINE INTELLIGENCE, 2021, 卷号: 3, 期号: 12, 页码: 1081-1089 作者:  Bai, Xiangd;  Wang, Hanchen;  Ma, Liya;  Xu, Yongchao;  Gan, Jiefeng 收藏  |  浏览/下载：51/0  |  提交时间：2022/01/18 Picture-word order compound protein interaction: Predicting compound-protein interaction using structural images of compounds 期刊论文 JOURNAL OF COMPUTATIONAL CHEMISTRY, 2021, 页码: 10 作者:  Qian, Ying;  Li, Xuelian;  Wu, Jian;  Zhou, Aimin;  Xu, Zhijian 收藏  |  浏览/下载：23/0  |  提交时间：2022/01/04 compound-protein interaction  convolutional neural network (CNN)  drug-drug interaction  image processing  structural images   M2 macrophage microvesicle-inspired nanovehicles improve accessibility to cancer cells and cancer stem cells in tumors 期刊论文 Journal of Nanobiotechnology, 2021, 卷号: 19, 期号: 1 作者:  Wang,Yuqi;  Gong,Xiang;  Li,Jie;  Wang,Hong;  Xu,Xiaoxuan 收藏  |  浏览/下载：42/0  |  提交时间：2021/12/16 Cancer stem cells  Macrophage  Microvesicle  Nanoparticles  Cabazitaxel   Discovery of a novel DDRs kinase inhibitor XBLJ-13 for the treatment of idiopathic pulmonary fibrosis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Dong, Ying;  Tang, Bi-xi;  Wang, Qi;  Zhou, Li-wei;  Li, Cong 收藏  |  浏览/下载：73/0  |  提交时间：2022/01/04 idiopathic pulmonary fibrosis  DDRs  kinase inhibitor  indazole derivatives  XBLJ-13  nintedanib  bleomycin-induced pulmonary fibrosismouse model   New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11 作者:  Zhang, Yong-Mei;  Ye, Lu-Yu;  Li, Tian-Yu;  Guo, Fan;  Guo, Fei 收藏  |  浏览/下载：22/0  |  提交时间：2022/01/04 YL-0919  medial prefrontal cortex  GABAergic neurons  5-HT1A receptor  GAD67-GFP transgenic mice  disinhibition  fluoxetine  electrophysiological recording   Inner nuclear membrane protein TMEM201 promotes breast cancer metastasis by positive regulating TGF beta signaling 期刊论文 ONCOGENE, 2021, 页码: 10 作者:  Kong, Ya;  Zhang, Yutian;  Wang, Hanlin;  Kan, Weijuan;  Guo, Haoran 收藏  |  浏览/下载：51/0  |  提交时间：2022/01/04