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科研机构
上海药物研究所 [33]
内容类型
期刊论文 [33]
发表日期
2021 [33]
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共33条,第1-10条
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发表日期:2021
专题:上海药物研究所
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A general strategy to the intracellular sensing of glycosidases using AIE-based glycoclusters
期刊论文
CHEMICAL SCIENCE, 2021, 卷号: 13, 期号: 1, 页码: 247-256
作者:
Dong, Lei
;
Zhang, Min-Yu
;
Han, Hai-Hao
;
Zang, Yi
;
Chen, Guo-Rong
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/01/18
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1
期刊论文
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2021, 页码: 14
作者:
Zhang, Chun
;
Sun, Yi-Tao
;
Gao, Li-Xin
;
Feng, Bo
;
Yan, Xue
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/01/18
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:
Zou, Hui-xi
;
Zhang, Yu-feng
;
Zhong, Da-fang
;
Jiang, Yong
;
Liu, Fei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
furmonertinib
autoinduction
food effect
alkaline phosphatase
body weight
pharmacokinetics
modeling and simulation
NSCLC
SN38-based albumin-binding prodrug for efficient targeted cancer chemotherapy
期刊论文
JOURNAL OF CONTROLLED RELEASE, 2021, 卷号: 339, 页码: 297-306
作者:
Huang, Ying
;
Wang, Lei
;
Cheng, Zhiyang
;
Yang, Biyu
;
Yu, Jiahui
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/12/01
Antitumour
Chemotherapy
SN38
Drug delivery systems
Albumin
Two New Oleanane-Triterpenoid Saponins from Clinopodium gracile
期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 页码: 8
作者:
Zhao, Ting
;
Liu, Yi-Nan
;
Sun, Xin-Yu
;
Li, Jing-Ya
;
Lei, Chun
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Clinopodium gracile
Lamiaceae
triterpenoid saponins
oleanane
Progression and Regression of Abdominal Aortic Aneurysms in Mice
期刊论文
CURRENT MEDICAL SCIENCE, 2021, 页码: 8
作者:
Ding, Yu-chao
;
Zhang, Xian-jing
;
Zhang, Ji-xiu
;
Zhai, Zi-yi
;
Zhang, Mei-xia
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2021/12/01
abdominal aortic aneurysm
disease progression
disease regression
elastogenesis
lysyl oxidase
Discovery of a Potential Liver Fibrosis Inhibitor from a Mushroom Endophytic Fungus by Genome Mining of a Silent Biosynthetic Gene Cluster
期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 卷号: 69, 期号: 38, 页码: 11303-11310
作者:
Cheng, Jin-Tao
;
Wang, Han-Min
;
Yu, Jia-Hui
;
Sun, Chen-Fan
;
Cao, Fei
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2021/12/01
fungus
Calcarisporium arbuscula
natural product
gene cluster activation
liver fibrosis
Strategy of De Novo Design toward First-In-Class Imaging Agents for Simultaneously Differentiating Glioma Boundary and Grades
期刊论文
ACS SENSORS, 2021, 卷号: 6, 期号: 9, 页码: 3330-3339
作者:
Yan, Feng
;
Zhuang, Jianfeng
;
Yu, Qian
;
Dou, Zhangqi
;
Jiang, Xuefeng
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/04
fluorescent probe
bioinformatics analysis
PDGFR beta
glioma imaging
glioma grading
Forrestiacids A and B, Pentaterpene Inhibitors of ACL and Lipogenesis: Extending the Limits of Computational NMR Methods in the Structure Assignment of Complex Natural Products
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 页码: 7
作者:
Xiong, Juan
;
Zhou, Peng-Jun
;
Jiang, Hao-Wen
;
Huang, Ting
;
He, Yu-Hang
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2021/11/04
forrestiacids
lipogenesis inhibitors
natural products
structure elucidation
terpenoids
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