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浏览/检索结果: 共13条，第1-10条 帮助 限定条件 发表日期：2021    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Rapamycin recruits SIRT2 for FKBP12 deacetylation during mTOR activity modulation in innate immunity 期刊论文 ISCIENCE, 2021, 卷号: 24, 期号: 11, 页码: 22 作者:  Hu, Lin;  Chen, Fuxian;  Wu, Chao;  Wang, Jun;  Chen, Si-si 收藏  |  浏览/下载：38/0  |  提交时间：2022/01/18 Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Zhou, Yu-bo;  Zhang, Yang-ming;  Huang, Hong-hui;  Shen, Li-jing;  Han, Xiao-feng 收藏  |  浏览/下载：93/0  |  提交时间：2021/11/04 multiple myeloma  HDAC inhibitor  bisthianostat  pharmacodynamics  pharmacokinetics  phase 1a clinical trial  antitumor drug   A facile method for vancomycin C-terminus functionalization and derivatization through hydrazide 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 42, 页码: 6 作者:  Hu, Yu;  Zou, Xiangman;  Shi, Weiwei;  Ma, Chenhui;  Chen, Feifei 收藏  |  浏览/下载：17/0  |  提交时间：2021/08/17 Vancomycin C-terminus modification  Hydrazide derivatives  Native Chemical Ligation  Antibacterial activity   Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 215, 页码: 13 作者:  Gao, Feng;  Chen, Xiaoxu;  Lu, Junyan;  Hu, Shulei;  Xu, Hui 收藏  |  浏览/下载：43/0  |  提交时间：2021/05/24 Ceramide analogs  AKT inhibitor  MK2206  Colon cancer  Combination therapy   Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa 期刊论文 CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 4, 页码: 295-304 作者:  Yao Shuai;  Zhang Jian-Qing;  Hou Jin-Jun;  Hu Xiao-Su;  Wang Ling 收藏  |  浏览/下载：55/0  |  提交时间：2021/06/11 High performance thin-layer chromatography  Mass spectrometry QDa  Ganoderma  Authentication   Simple and robust differentiation of Ganoderma species by high performance thin-layer chromatography coupled with single quadrupole mass spectrometry QDa 期刊论文 CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 4, 页码: 295-304 作者:  Yao Shuai;  Zhang Jian-Qing;  Hou Jin-Jun;  Hu Xiao-Su;  Wang Ling 收藏  |  浏览/下载：57/0  |  提交时间：2021/06/11 High performance thin-layer chromatography  Mass spectrometry QDa  Ganoderma  Authentication   Downregulation of c-Myc expression confers sensitivity to CHK1 inhibitors in hematologic malignancies 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9 作者:  Jiang, Kai-long;  Tong, Le-xian;  Wang, Tao;  Wang, Han-lin;  Hu, Xiao-bei 收藏  |  浏览/下载：51/0  |  提交时间：2021/05/24 CHK1 inhibitors  PY34  drug sensitivity  c-Myc  hematologic malignancies   A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia 期刊论文 Alzheimer's Research & Therapy, 2021, 卷号: 13, 期号: 1 作者:  Xiao,Shifu;  Chan,Piu;  Wang,Tao;  Hong,Zhen;  Wang,Shuzhen 收藏  |  浏览/下载：149/0  |  提交时间：2021/05/24 Sodium oligomannate  Efficacy  Safety  Alzheimer’s disease  Clinical trial   Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403 作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong 收藏  |  浏览/下载：57/0  |  提交时间：2021/05/24 SIRT1  inhibitor  structure-activity relationship  interaction  deacetylase   Reply to: Binding site for MDL-801 on SIRT6 期刊论文 NATURE CHEMICAL BIOLOGY, 2021, 页码: 5 作者:  Huang, Zhimin;  Zhao, Junxing;  Deng, Wei;  Chen, Yingyi;  Shang, Jialin 收藏  |  浏览/下载：64/0  |  提交时间：2021/05/24