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科研机构
上海药物研究所 [9]
内容类型
期刊论文 [9]
发表日期
2020 [9]
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发表日期:2020
专题:上海药物研究所
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DCZ3301, an aryl-guanidino agent, inhibits ocular neovascularization via PI3K/AKT and ERK1/2 signaling pathways
期刊论文
EXPERIMENTAL EYE RESEARCH, 2020, 卷号: 201, 页码: 8
作者:
Xu, Kai
;
Li, Bo
;
Zhang, Shujie
;
Hu, Fangyuan
;
Xu, Zhijian
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
DCZ3301
Apoptosis
PI3K/AKT pathway
ERK1/2 pathway
Choroid microvascular sprouting
Corneal neovascularization
Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yu, Ming-cheng
;
Yang, Feng
;
Ding, Xiao-yu
;
Sun, Nan-nan
;
Jiang, Zheng-yuan
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2020/12/24
RORγ
t
cocrystal structures
MD simulation
“
short”
inverse agonists
agonists
“
long”
inverse agonists
Two new flavonoid glycosides isolated from the fruits of Catalpa ovata
期刊论文
PHARMACOGNOSY MAGAZINE, 2020, 卷号: 16, 期号: 72, 页码: 812-816
作者:
Zhang, Liu-Qiang
;
Xue, Hai-Bing
;
Zhu, Wei-Liang
;
Li, Yi-Ming
;
Chen, Kai-Xian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/05/24
Antioxidant activity
Catalpa ovata
flavonoid glycosides
polyphenols
structure–
activity relationship
Hepatoprotective effects of total phenylethanoid glycosides from Acanthus ilicifolius L. against carbon tetrachloride-induced hepatotoxicity
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 256, 页码: 8
作者:
Zhang, Meng-Qi
;
Ren, Xia
;
Zhao, Qing
;
Yue, Shi-Jun
;
Fu, Xiu-Mei
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/07/01
Acanthus ilicifolius L.
Total phenylethanoid glycosides
Hepatoprotective
Antioxidant
Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9
作者:
Wu, Qihao
;
Li, Song-Wei
;
Xu, Heng
;
Wang, Hong
;
Hu, Pei
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
biomimetic synthesis
biosynthetic rearrangements
marine natural products
polyketides
Sacoglossan mollusk
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 11
作者:
Guo, Shi-yan
;
Sun, Di
;
Ni, Da-long
;
Yu, Miao-rong
;
Qian, Kun
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
hypoxia relief
mesoporous calcium silicate
sequential functions
sustained drug release
synergetic effects
AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition (vol 0, pg 1, 2019)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 2
作者:
Zhang, Kai-li
;
Shen, Qian-qian
;
Fang, Yan-feng
;
Sun, Yi-ming
;
Ding, Jian
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Synthesis and Target Identification of Benzoxepane Derivatives as Potential Anti-Neuroinflammatory Agents for Ischemic Stroke
期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 卷号: 59, 期号: 6, 页码: 2429-2439
作者:
Gao, Cheng-Long
;
Hou, Gui-Ge
;
Liu, Jin
;
Ru, Tong
;
Xu, Ya-Zhou
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2020/07/01
anti-inflammatory
drug discovery
heterocycles
photoaffinity labeling
proteins
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