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浏览/检索结果: 共6条，第1-6条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Crystallography-guided discovery of carbazole-based retinoic acid-related orphan receptor gamma-t (ROR gamma t) modulators: insights into different protein behaviors with "short" and "long" inverse agonists 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Yu, Ming-cheng;  Yang, Feng;  Ding, Xiao-yu;  Sun, Nan-nan;  Jiang, Zheng-yuan 收藏  |  浏览/下载：85/0  |  提交时间：2020/12/24 RORγ  t  cocrystal structures  MD simulation  “  short”  inverse agonists  agonists  “  long”  inverse agonists   Sarsasapogenin improves adipose tissue inflammation and ameliorates insulin resistance in high-fat diet-fed C57BL/6J mice 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10 作者:  Yu, Yan-yan;  Cui, Shi-chao;  Zheng, Tian-nan;  Ma, Hai-jian;  Xie, Zhi-fu 收藏  |  浏览/下载：21/0  |  提交时间：2020/12/24 insulin resistance  sarsasapogenin  adipose tissue inflammation  macrophage-adipocyte crosstalk  IKK/NF-kappa B  JNK   Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors 期刊论文 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 11, 页码: 5 作者:  Satheeshkumar, Rajendran;  Zhu, Rui;  Feng, Bo;  Huang, Chao;  Gao, Ya 收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Heterocyclic bis-aryl amides  PTP1B  SHP2  Inhibitors  Structure-activity relationships (SAR)   Biomimetic metal-organic nanoparticles prepared with a 3D-printed microfluidic device as a novel formulation for disulfiram-based therapy against breast cancer 期刊论文 APPLIED MATERIALS TODAY, 2020, 卷号: 18, 页码: 12 作者:  Chang, Ya;  Jiang, Jizong;  Chen, Wu;  Yang, Wen;  Chen, Lili 收藏  |  浏览/下载：52/0  |  提交时间：2020/07/01 Biomimetic delivery  Metal-organic nanoparticle  Disulfiram  Copper diethyldithiocarbamate  Microfluidic  Breast cancer   Inhibition of human thrombin by the constituents of licorice: inhibition kinetics and mechanistic insights through in vitro and in silico studies 期刊论文 RSC ADVANCES, 2020, 卷号: 10, 期号: 7, 页码: 3626-3635 作者:  Shi, Cheng-Cheng;  Chen, Tian-Ran;  Zhang, Qi-Hua;  Wei, Ling-Hua;  Huang, Chao 收藏  |  浏览/下载：19/0  |  提交时间：2020/07/01 Phytochemical and biological studies on rare and endangered plants endemic to China. Part XV. Structurally diverse diterpenoids and sesquiterpenoids from the vulnerable conifer Pseudotsuga sinensis 期刊论文 PHYTOCHEMISTRY, 2020, 卷号: 169, 页码: 14 作者:  Huang, Ting;  Ying, Sheng-Hui;  Li, Jing-Ya;  Chen, Hao-Wei;  Zang, Yi 收藏  |  浏览/下载：72/0  |  提交时间：2020/07/01 Pseudotsuga sinensis dode  Pinaceae  Rare and endangered plants (REPs)  Degraded diterpenoids  Pseudosinins  ATP-Citrate lyase (ACL)