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浏览/检索结果: 共22条，第1-10条 帮助 限定条件 发表日期：2020    专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Large-scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells 期刊论文 CELL REPORTS, 2020, 卷号: 33, 期号: 10, 页码: 24 作者:  Feng, Sisi;  Wu, Jiaying;  Qiu, Wei-Lin;  Yang, Li;  Deng, Xiaogang 收藏  |  浏览/下载：40/0  |  提交时间：2021/05/24 Identify potent SARS-CoV-2 main protease inhibitors via accelerated free energy perturbation-based virtual screening of existing drugs 期刊论文 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 卷号: 117, 期号: 44, 页码: 27381-27387 作者:  Li, Zhe;  Li, Xin;  Huang, Yi-You;  Wu, Yaoxing;  Liu, Runduo 收藏  |  浏览/下载：75/0  |  提交时间：2020/12/24 virtual screening  SARS-CoV-2  drug repurposing  free energy perturbation  main protease   Antispasmodic Drug Drofenine as an Inhibitor of Kv2.1 Channel Ameliorates Peripheral Neuropathy in Diabetic Mice 期刊论文 ISCIENCE, 2020, 卷号: 23, 期号: 10, 页码: 56 作者:  Xu, Xiaoju;  Xu, Xu;  Hao, Yanping;  Zhu, Xialin;  Lu, Jian 收藏  |  浏览/下载：28/0  |  提交时间：2021/05/24 Identification and characterization of isocitrate dehydrogenase 1 (IDH1) as a functional target of marine natural product grincamycin B 期刊论文 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 13 作者:  Wang, Zheng;  Li, Zeng-xia;  Zhao, Wen-cao;  Huang, Hong-bo;  Wang, Jia-qi 收藏  |  浏览/下载：82/0  |  提交时间：2020/12/24 grincamycin B  marine natural product  isocitrate dehydrogenase 1  apoptosis  ER stress  intracellular ROS  Zebrafish embryos  hematological malignancies   Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain 期刊论文 BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11 作者:  Chen, Yu;  Bi, Xiaoyang;  Zhang, Fengcai;  Sun, Zhongya;  Xu, Pan 收藏  |  浏览/下载：24/0  |  提交时间：2020/12/24 In silico screening  Drug design  CBP  Bromodomain  Inhibitor  Acute Myeloblastic Leukemia   Alleviation of Synovial Inflammation of Juanbi-Tang on Collagen-Induced Arthritis and TNF-Tg Mice Model (vol 11, 45, 2020) 期刊论文 FRONTIERS IN PHARMACOLOGY, 2020, 卷号: 11, 页码: 2 作者:  Wang, Tengteng;  Jia, Qingyun;  Chen, Tao;  Yin, Hao;  Tian, Xiaoting 收藏  |  浏览/下载：37/0  |  提交时间：2020/12/24 Juanbi-Tang  rheumatoid arthritis  collagen-induced arthritis  synoviocyte  tumor necrosis factor   Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors 期刊论文 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 卷号: 142, 期号: 22, 页码: 9982-9992 作者:  Song, Bichao;  Xie, Peipei;  Li, Yingzi;  Hao, Jiping;  Wang, Lu 收藏  |  浏览/下载：22/0  |  提交时间：2020/12/24 Complex Polypropionates from a South China Sea Photosynthetic Mollusk: Isolation and Biomimetic Synthesis Highlighting Novel Rearrangements 期刊论文 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 9 作者:  Wu, Qihao;  Li, Song-Wei;  Xu, Heng;  Wang, Hong;  Hu, Pei 收藏  |  浏览/下载：38/0  |  提交时间：2020/07/01 biomimetic synthesis  biosynthetic rearrangements  marine natural products  polyketides  Sacoglossan mollusk   Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion 期刊论文 ADVANCED SCIENCE, 2020, 页码: 13 作者:   收藏  |  浏览/下载：107/0  |  提交时间：2020/07/01 anti-metastasis activities  crystal structures  inhibitors  novel pockets  rho family proteins   A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation 期刊论文 NATURE COMMUNICATIONS, 2020, 卷号: 11, 期号: 1, 页码: 8 作者:  Chen, Lu;  Quan, Haitian;  Xu, Zhongliang;  Wang, Hao;  Xia, Yuanzhi 收藏  |  浏览/下载：17/0  |  提交时间：2020/12/24