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Discovery and characterization of a novel highly potent and selective type II native and drug-resistant V299L mutant BCR-ABL inhibitor (CHMFL-ABL-039) for Chronic Myeloid Leukemia (CML) 期刊论文
CANCER BIOLOGY & THERAPY, 2019, 卷号: 20, 期号: 6, 页码: 877-885
作者:  Wu, Jiaxin;  Wang, Aoli;  Li, Xixiang;  Chen, Cheng;  Qi, Ziping
收藏  |  浏览/下载:29/0  |  提交时间:2019/11/27
Discovery of N-(4-(6-Acetamidopyrimidin-4-yloxy)phenyl)-2-(2-(trifluoromethyl)phenyl)acetamide (CHMFL-FLT3-335) as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication (FLT3-ITD) Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 2, 页码: 875-892
作者:  Liang, Xiaofei;  Wang, Beilei;  Chen, Cheng;  Wang, Aoli;  Hu, Chen
收藏  |  浏览/下载:20/0  |  提交时间:2020/05/21
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
Journal of Medicinal Chemistry, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Tingting Lu;  Jian Ge;  Tao Ren;  Wenchao Wang;  Junjie Wang
收藏  |  浏览/下载:36/0  |  提交时间:2019/04/24
Discovery of N-phenyl)-2-phenyl)acetamide as a Potent FMS-like Tyrosine Kinase 3 Internal Tandem Duplication Mutant Selective Inhibitor for Acute Myeloid Leukemia 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: Vol.62 No.2, 页码: 875-892
作者:  Wang, Beilei;  Li, Feng;  Liu, Qingwang;  Hu, Zhenquan;  Liang, Xiaofei
收藏  |  浏览/下载:4/0  |  提交时间:2019/04/24
Repurposing cabozantinib to GISTs: Overcoming multiple imatinib-resistant cKIT mutations including gatekeeper and activation loop mutants in GISTs preclinical models 期刊论文
CANCER LETTERS, 2019, 页码: 105-114
作者:  Lu, Tingting;  Chen, Cheng;  Wang, Aoli;  Jiang, Zongru;  Qi, Ziping
收藏  |  浏览/下载:14/0  |  提交时间:2020/07/14


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