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科研机构
上海药物研究所 [25]
内容类型
期刊论文 [25]
发表日期
2019 [25]
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发表日期:2019
专题:上海药物研究所
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Discovery and biological evaluation of vinylsulfonamide derivatives as highly potent, covalent TEAD autopalmitoylation inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 15
作者:
Lu, Wenchao
;
Wang, Jun
;
Li, Yong
;
Tao, Hongru
;
Xiong, Huan
收藏
  |  
浏览/下载:94/0
  |  
提交时间:2020/07/01
Hippo pathway
TEAD transcription factor
Covalent inhibitor
Palmitoylation inhibitor
Effective Virtual Screening Strategy toward heme-containing proteins: Identification of novel IDO1 inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 184, 页码: 23
作者:
Zou, Yi
;
Hu, Yue
;
Ge, Shushan
;
Zheng, Yingbo
;
Li, Yuezhen
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2020/07/01
IDO1
Heme
T cell
Cancer immunotherapy
Virtual screening
Drug design
Molecular dynamics simulation
Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: In vivo and in vitro studies
期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2019, 卷号: 244, 页码: 10
作者:
Zhao, Qing
;
Ren, Xia
;
Chen, Min
;
Yue, Shi-Jun
;
Zhang, Meng-Qi
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Formula Le-Cao-Shi
Hepatitis B virus
Anti-Hepatitis B
Co-delivery of docetaxel and silibinin using pH-sensitive micelles improves therapy of metastatic breast cancer (vol 38, pg 1655, 2017)
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 9, 页码: 1258-1258
作者:
Dong, Xin-yue
;
Lang, Tian-qun
;
Yin, Qi
;
Zhang, Peng-cheng
;
Li, Ya-ping
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2020/07/01
Hepatoprotective effects of a traditional Chinese medicine formula against carbon tetrachloride-induced hepatotoxicity in vivo and in vitro
期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2019, 卷号: 117, 页码: 8
作者:
Ren, Xia
;
Xin, Lan-Ting
;
Zhang, Meng-Qi
;
Zhao, Qing
;
Yue, Shi-Yun
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Traditional Chinese medicine
Le-Cao-Shi formula
Acute liver injury
Hepatoprotective effect
SNORD89 promotes stemness phenotype of ovarian cancer cells by regulating Notch1-c-Myc pathway
期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 卷号: 17, 期号: 1, 页码: 15
作者:
Zhu, Wenjing
;
Niu, Jumin
;
He, Miao
;
Zhang, Liwen
;
Lv, Xuemei
收藏
  |  
浏览/下载:95/0
  |  
提交时间:2020/07/01
Ovarian cancer stem cells
TCGA
SNORNAs
SNORD89
Highly diverse cembranoids from the South China Sea soft coral Sinularia scabra as a new class of potential immunosuppressive agents
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3469-3476
作者:
Yang, Min
;
Li, Heng
;
Zhang, Quan
;
Wu, Qi-Hao
;
Li, Geng
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2020/07/01
Marine natural products
Cembranoids
Soft coral
Sinularia scabra
Immunosuppressive activity
Structure-activity relationship
Inhibition of G9a by a small molecule inhibitor, UNC0642, induces apoptosis of human bladder cancer cells
期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 8, 页码: 1076-1084
作者:
Cao, Yue-peng
;
Sun, Jing-ya
;
Li, Mei-qian
;
Dong, Yu
;
Zhang, Yuan-heng
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
human urinary bladder cancer
G9a
UNC0642
apoptosis
Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer
期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 15
作者:
Jin, Nan
;
Bi, Aiwei
;
Lan, Xiaojing
;
Xu, Jun
;
Wang, Xiaomin
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/07/01
Effects of strontium substitution on the structural distortion of hydroxyapatite by rietveld refinement and Raman Spectroscopy
期刊论文
CERAMICS INTERNATIONAL, 2019, 卷号: 45, 期号: 8, 页码: 11073-11078
作者:
Cheng, Guofeng
;
Zhang, Yong
;
Yin, Handi
;
Ruan, Yinjie
;
Sun, Yue
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/07/01
Strontium (Sr) substitution hydroxyapatite (HA)
Structural distortion
Occupation
Rietveld refinement
Raman spectroscopy
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