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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 发表日期：2018     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Discovery of (E)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)propanamide (CHMFL-ABL-121) as a highly potent ABL kinase inhibitor capable of overcoming a variety of ABL mutants including T315I for chronic myeloid leukemia 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 160, 页码: 61-81 作者:  Liu, Xuesong;  Wang, Beilei;  Chen, Cheng;  Jiang, Zongru;  Hu, Chen 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/11 ABL kinase  Kinase inhibitor  ABL mutant  CML   Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Jiaxin;  Wu, Yun;  Chen, Cheng;  Zou, Fengming 收藏  |  浏览/下载：66/0  |  提交时间：2019/12/25 CDK9  Kinase inhibitor  Structure-activity relationship  Leukemia   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3K delta) inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 156, 页码: 831-846 作者:  Liang, Xiaofei;  Li, Feng;  Chen, Cheng;  Jiang, Zongru;  Wang, Aoli 收藏  |  浏览/下载：14/0  |  提交时间：2019/12/10 PI3K delta  Kinase inhibitor  Acute myeloid leukemia  Structure-activity relationship   Discovery of (S)-2-amino-N-(5-(6-chloro-5-(3-methylphenylsulfonamido)pyridin-3-yl)-4-methylthiazol-2-yl)-3-methylbutanamide (CHMFL-PI3KD-317) as a potent and selective phosphoinositide 3-kinase delta (PI3Kδ) inhibitor 期刊论文 European Journal of Medicinal Chemistry, 2018, 卷号: Vol.156, 页码: 831-846 作者:  Zongru Jiang;  Wenliang Wang;  Fengming Zou;  Jing Liu;  Qingsong Liu 收藏  |  浏览/下载：7/0  |  提交时间：2019/04/22 PI3Kδ  Kinase  inhibitor  Acute  myeloid  leukemia  Structure-activity  relationship   Discovery of 4--4-amino) cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl) tetrahydro-2H-pyran-4-carbonitrile as a novel highly selective and potent CDK9 kinase inhibitor 期刊论文 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: Vol.158, 页码: 896-916 作者:  Wang, Beilei;  Wu, Yun;  Liu, Qingwang;  Jiang, Zongru;  Wu, Jiaxin 收藏  |  浏览/下载：8/0  |  提交时间：2019/04/24 CDK9  Kinase  inhibitor  Structure-activity  relationship  Leukemia   Isolation of a feather-degrading strain of bacterium from spider gut and the purification and identification of its three key enzymes 期刊论文 Molecular Biology Reports, 2018, 卷号: 45, 期号: 6, 页码: 1681-1689 作者:  Qu, Fang;  Chen, Qingwang;  Ding, Yiying;  Liu, Zihao;  Zhao, Yan 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/23 Feather degradation  Spider gut  Stenotrophomonas maltophilia  Symbiotic microorganism  Synergic enzymes   Development of a system of compatible individual tree diameter and aboveground biomass prediction models using error-in-variable regression and airborne LiDAR data 期刊论文 Remote Sensing, 2018, 卷号: 10, 期号: 2 作者:  Fu, Liyong;  Liu, Qingwang;  Sun, Hua;  Wang, Qiuyan;  Li, Zengyuan 收藏  |  浏览/下载：4/0  |  提交时间：2019/12/28 airborne LiDAR  diameter at breast height  aboveground biomass  error-in-variable models  leave-one-out cross-validation