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科研机构
中国医学科学院 北... [37]
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期刊论文 [34]
会议论文 [3]
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2019 [8]
2018 [4]
2017 [6]
2016 [2]
2015 [9]
2014 [2]
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专题:中国医学科学院 北京协和医学院
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Design, synthesis and biological evaluation of novel 4-anilinoquinazoline derivatives as hypoxia-selective EGFR and VEGFR-2 dual inhibitors
期刊论文
2019, 卷号: 181, 页码: 111552
作者:
Wei Huiqiang
;
Duan Yuqing
;
Gou Wenfeng
;
Cui Jie
;
Ning Hongxin
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2020/01/03
3-Nitro-1
2
4-triazole
EGFR
Hypoxia
Tyrosine kinase inhibitor
VEGFR-2
Vandetanib
TNFα inhibitor C87 sensitizes EGFRvIII transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling
期刊论文
2019, 卷号: 16, 期号: 3, 页码: 606-617
作者:
Ma Li
;
She Chunhua
;
Shi Qian
;
Yin Qiang
;
Ji Xinxin
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2020/01/03
EGFR
Glioblastoma
TNFα
drug resistance
inhibitor
Corrigendum to "A high-performance liquid chromatography-tandem mass spectrometry method for the analysis of lifirafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine, and its application in a clinical pharmacokinetic study" [J. Pharm
期刊论文
2019
作者:
Yao Xueting
;
Song Ling
;
Liu Yang
;
Wang Huanhuan
;
Liu Jie
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Circular RNA profiling identified as a biomarker for predicting the efficacy of Gefitinib therapy or non-small cell lung cancer
期刊论文
2019, 卷号: 11, 期号: 5, 页码: 1779-+
作者:
Liu, Yu-Tao
;
Han, Xiao-Hong
;
Xing, Pu-Yuan
;
Hu, King-Sheng
;
Hao, Xue-Zhi
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
Non-small cell lung cancer (NSCLC)
circular RNA (circRNA)
epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI)
predictive biomarker
A novel PI3K/mTOR dual inhibitor XH002 exhibited robust antitumor activity in NSCLC
期刊论文
2019, 卷号: 27, 期号: 4, 页码: 451-459
作者:
Lv, Yuanhao
;
Du, Tingting
;
Ji, Ming
;
Wang, Chunyang
;
Lin, Songwen
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
XH002
PI3K
mTOR
NSCLC
EGFR
T790M
Safety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer: results of a phase Ib trial
期刊论文
2019, 卷号: 11, 页码: 4449-4459
作者:
Hu, Xing-Sheng
;
Han, Xiao-Hong
;
Yang, Sheng
;
Li, Ning
;
Wang, Lin
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
simotinib
EGFR
non-small cell lung cancer
toxicity
pharmacokinetics
Apatinib, a novel VEGFR inhibitor plus docetaxel in advanced lung adenocarcinoma patients with wild-type EGFR: a phase I trial
期刊论文
2019, 卷号: 37, 期号: 4, 页码: 731-737
作者:
Duan, Jian-Chun
;
Wang, Zhi-Jie
;
Lin, Lin
;
Li, Jun-Ling
;
Wang, Yan
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2020/01/03
Apatinib
Docetaxel
Lung adenocarcinoma
Wild-type EGFR
A high-performance liquid chromatography-tandem mass spectrometry method for the determination of lifrafenib, a novel RAF kinase and EGFR inhibitor, in human plasma and urine and its application in clinical pharmacokinetic study
期刊论文
2019, 卷号: 166, 页码: 20-29
作者:
Yao, Xueting
;
Song, Ling
;
Liu, Yang
;
Wang, Huanhuan
;
Liu, Jie
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2020/01/03
HPLC-MS/MS
Pharmacokinetics
BRAF V600E
EGFR
Lifirafenib
Real-world EGFR testing in patients with stage IIIB/IV non-small-cell lung cancer in North China: A multicenter, non-interventional study
期刊论文
2018, 卷号: 9, 期号: 11, 页码: 1461-1469
作者:
Cheng, Ying
;
Wang, Yan
;
Zhao, Jun
;
Liu, Yunpeng
;
Gao, Hongjun
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2020/01/03
Clinical practice
epidermal growth factor receptor
mutation
non-small-cell lung cancer
tyrosine kinase inhibitor
Comparison of up-front radiotherapy and TKI with TKI alone for NSCLC with brain metastases and EGFR mutation: A meta-analysis
期刊论文
2018, 卷号: 122, 页码: 94-99
作者:
Wang, Chunyu
;
Lu, Xiaotong
;
Lyu, Zhangyan
;
Bi, Nan
;
Wang, Luhua
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2020/01/03
Non-small cell lung cancer
EGFR mutation
Brain metastases
Radiotherapy
Tyrosine kinase inhibitor
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