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科研机构
中南大学 [8]
内容类型
期刊论文 [8]
发表日期
2018 [1]
2017 [2]
2012 [1]
2011 [2]
2009 [2]
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Astragaloside IV Improves Vasodilatation Function by Regulating the PI3K/Akt/eNOS Signaling Pathway in Rat Aorta Endothelial Cells
期刊论文
Journal of Vascular Research, 2018, 卷号: 55, 期号: 3, 页码: 169-176
作者:
Lin, Xiang-Ping
;
Cui, Han-Jin
;
Yang, A-Li
;
Luo, Jie-Kun
;
Tang, Tao*
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
*Astragaloside IV
*Endothelial nitric oxide synthase
*Huang Qi (Astragalus)
*PI3K/Akt/eNOS pathway
*Vasorelaxation
Metformin, beyond an insulin sensitizer, targeting heart and pancreatic β cells
期刊论文
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2017, 卷号: 1863, 期号: 8, 页码: 1984-1990
作者:
Yang, Xin
;
Xu, Zhipeng
;
Zhang, Chunlan
;
Cai, Zixin
;
Zhang, Jingjing*
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/12/03
A1c
glycated hemoglobin
AACE
American Association of Clinical Endocrinologists
ACC
acetyl-CoA carboxylase
ADA
American Diabetes Association
Akt/PKB
tyrosine kinase/protein kinase B
AMP
adenosine monophosphate
AMPK
adenosine monophosphate-activated protein
Ang II
angiotensin II
ATP
adenosine triphosphate
BAT
brown adipose tissue
CHOP
CEBP-homologous protein
CEBP
CCAAT enhancer binding protein
CoA
coenzyme A
DPP
Diabetes Prevention Program
EASD
European Association for the Study of Diabetes
eNOS
endothelial nitric oxide synthase
ER
endoplasmic reticulum
FDA
Food and Drug Administration
FFA
free fatty acid
FOXO1
forkhead box protein O1
G6P
glucose 6-phosphate
GDM
gestational diabetes mellitus
GIPR
glucose-dependent insulinotropic polypeptide receptor
GLP-1R
glucagon-like peptide-1 receptor
GLUT1
glucose transporter-1
GLUT4
glucose transporter type 4
GLUTs
glucose transporters
G6P
glucose 6-phosphate, glucose transporter-1
GPR40
G protein-coupled receptor 40
HbA1c
hemoglobin A1c
HGP
hepatic glucose production
HSL
hormone sensitive lipase
IL-6
interleukin 6
INS-1
insulinoma cells in rat
IR
insulin resistance
IRS-1
insulin receptor substrate 1
JNK
c-Jun. N-terminal kinase
Kir6.2
inwardly rectifying potassium/kalium channel
LDs
lipid droplets
LDL
low density lipoprotein
LV
left ventricular
MIN6 cells
mouse insulinoma cells
MAPK
mitogen-activated protein kinases
mPTP
mitochondrial permeability transition pore opening
mTOR
mammalian target of rapamycin
NADPH
nicotinamide adenine dinucleotide phosphate
NF-kappaB
nuclear factors-kappa B
NIT-1 cells
insulinoma cells
p70S6K
p70 ribosomal S6 kinase
PA
palmitic acid
NOS
NADPH oxidase
p38 MAPK
p38 mitogen-activated protein kinase
PA
palmitic acid
PCOS
polycystic ovary syndrome
PGC-1α
peroxisome proliferator-activated receptor-g coactivator-1α
PI3K
phosphatidylinositol 3-kinase
PKB
protein kinase B
PKC
protein kinase C
PPARα
peroxisome-proliferator activated receptor α
PTP
permeability transition pore
RCT
randomized controlled trial
RISK
reperfusion injury salvage kinase
ROS
reactive oxygen species
SERCA2
reticulum sarcoplasmic Ca2 +-ATPase
RISK
reperfusion injury salvage kinase
Smad3
mothers against decapentaplegic homolog 3
SRC-2
steroid receptor coactivator 2
T1DM
Type 1 diabetes mellitus
T2DM
Type 2 diabetes mellitus
TGFβ1
transforming growth factor β1
TLR4
Toll-like receptor
TNF-α
tumor necrosis factor α
TR4
testicular receptor 4
UKPDS
United Kingdom Prospective Diabetes Study
VLDL
very low density lipoprotein
Metformin
Pancreatic β Cells
Heart failure
Insulin sensitizer
Puerarin inhibits expression of tissue factor induced by oxidative low-density lipoprotein through activating the PI3K/Akt/eNOS pathway and inhibiting activation of ERK1/2 and NF-κB
期刊论文
Life Sciences, 2017, 卷号: 191, 页码: 115-121
作者:
Deng, Hua-Fei
;
Wang, Xiao-Li
;
Sun, Hui
;
Xiao, Xian-Zhong*
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Endothelial cells
Mitogen-activated protein kinases
Nuclear factor-kappaB
Oxidative low-density lipoprotein
Phosphoinositide 3-kinase/Akt/endothelial nitric oxide synthase
Puerarin
Tissue factor
Remote ischemic postconditioning protects the brain from global cerebral ischemia/reperfusion injury by up-regulating endothelial nitric oxide synthase through the PI3K/Akt pathway
期刊论文
Brain Research, 2012, 卷号: 1445, 页码: 92-102
作者:
Peng, Bei
;
Guo, Qu-Lian
;
He, Zhi-Jing
;
Ye, Zhi
;
Yuan, Ya-Jing
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2019/12/03
4-VO
four-vessel occlusion
ANOVA
analysis of variance
CCAs
common carotid arteries
DMSO
dimethyl sulfoxide
eNOS
endothelial nitric oxide synthase
I/R
ischemia and reperfusion
iNOS
inducible nitric oxide synthase
L-NAME
N(ω)-nitro-l-arginine methyl ester
l
LY
LY294002
nNOS
neuronal nitric oxide synthase
NO
nitric oxide
NOS
nitric oxide synthase
PI3K
phosphoinositide-3 kinase
RIPoC
remote ischemic postconditioning
TUNEL
terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling
Global cerebral ischemia
Remote ischemic postconditioning
Delayed neuronal death
Phosphatidylinositol-3 kinase/Akt
Endothelial nitric oxide synthase
Inhibition of ceramide synthesis reverses endothelial dysfunction and atherosclerosis in streptozotocin-induced diabetic rats
期刊论文
Diabetes Research and Clinical Practice, 2011, 卷号: 93, 期号: 1, 页码: 77-85
作者:
Li Chun
;
Zhou Junlin
;
Wang Aimin
;
Li Niansheng
;
Chen Benmei
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2019/12/03
DC group
diabetic control group
NC group
normal control group
MTD group
myriocin treated diabetic group
SPT
serine palmitoyl-CoA transferase
EDVD
endothelium-dependent vasodilation
EC
endotheliocyte
IRS
insulin receptor substrate
PI3K
phosphatidylinositol 3-kinase
AKT/PKB
protein kinase B
eNOS
endothelial nitric oxide synthase
NO
nitric oxide
TNF-a
tumor necrosis factor α
HUVECs
human umbilical vein endothelial cells
Homa-IR
homeostasis model assessment-insulin resistance
HbA1c
glycated hemoglobin A1c
TG
triglyeride
TC
total cholesterol
LDL
low density lipoprotein
HDL
high density lipoprotein
ALT
alanine aminotransferase
AST
aspartate aminotransferase
FBS
fasting blood sugar
PBS
postprandial blood sugar
Qod
quaque (other) die
Ceramide
EDVD
eNOS
Atherosclerosis
A(2B) adenosine receptor contributes to penile erection via PI3K/AKT signaling cascade-mediated eNOS activation
期刊论文
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2011, 卷号: 25, 期号: 8, 页码: 2823-30
作者:
Wen, Jiaming
;
Grenz, Almut
;
Zhang, Yujin
;
Dai, Yingbo
;
Kellems, Rodney E.
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2019/12/03
shear stress
vascular tone
CD73
erectile function
Rosiglitazone inhibits high glucose-induced apoptosis in human umbilical vein endothelial cells through the PI3K/Akt/eNOS pathway
期刊论文
Canadian Journal of Physiology and Pharmacology, 2009, 卷号: 87, 期号: 7, 页码: 549-555
作者:
Wu, Jing
;
Lei, Min-Xiang
;
Xie, Xiao-Yun
;
Liu, Lan
;
She, Yan-Mei
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/03
Akt
Caspase-3
NO
PI3K
Rosiglitazone
eNOS
Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells
期刊论文
Medical science monitor : international medical journal of experimental and clinical research, 2009, 卷号: 15, 期号: 9, 页码: BR254-BR261
作者:
Xiao-Yun, Xie
;
Zhuo-Xiong, Chen
;
Min-Xiang, Lei
;
Xingxuan, He
;
Schuchman, Edward H
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/03
palmitate
ceramide
nitric oxide synthase (NOS)
signal transduction pathway
insulin
HUVEC
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