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科研机构
山东大学 [16]
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期刊论文 [16]
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2019 [1]
2017 [1]
2016 [1]
2015 [2]
2013 [1]
2012 [4]
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共16条,第1-10条
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专题:山东大学
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Design, synthesis, and biological evaluation of novel nitrogen heterocycle-containing ursolic acid analogs as antitumor agents
期刊论文
Molecules, 2019
作者:
Wang W.
;
Lei L.
;
Liu Z.
;
Wang H.
;
Meng Q.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/11
Antitumor activity
Apoptosis
Nitrogen heterocycles
Synthesis
Ursolic acid analogues
Design, synthesis and primary biological evaluation of the novel 2-pyridone derivatives as potent non-nucleoside HBV inhibitors
期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 136, 页码: 144-153
作者:
Jia, Haiyong
;
Song, Yang
;
Yu, Ji
;
Zhan, Peng
;
Rai, Diwakar
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2019/12/12
HBV
Heterocycle
Bioisosterism
Hybrid pharmacophore-based
SAR
Synthesis of ferrocene[c]pyridin-2(1H)-one derivatives via Pd(II)-catalyzed C-H activation reaction under air
期刊论文
TETRAHEDRON LETTERS, 2016, 卷号: 57, 期号: 42, 页码: 4676-4679
作者:
Liu, Hua-Yu
;
Mou, Rui-Qi
;
Sun, Chuan-Zhi
;
Zhang, Sheng-Yan
;
Guo, Dian-Shun
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  |  
浏览/下载:3/0
  |  
提交时间:2019/12/16
Palladium-catalysis
C-H activation
N-Methoxy amide
Ferrocene-fused
heterocycle
Annulation
Synthesis and Preliminary Antiviral Activities of Piperidine-substituted Purines against HIV and Influenza A/H1N1 Infections
期刊论文
CHEMICAL BIOLOGY & DRUG DESIGN, 2015, 卷号: 86, 期号: 4, 页码: 568-577
作者:
Kang, Dongwei
;
Fang, Zengjun
;
Huang, Boshi
;
Zhang, Lingzi
;
Liu, Huiqing
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
bioactivity
heterocycle
HIV
influenza virus
NNRTIs
structure-activity relationship
synthesis
Efficient synthesis of pyrrolo[2,3-d]pyrimidines via a Cu(I)/6-methylpicolinic acid catalyzed coupling reaction
期刊论文
Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry, 2015, 卷号: 56, 期号: 23, 页码: 3259-3261
作者:
Jiang, Xi
;
Sun, Dequn
;
Jiang, Yongwen
;
Ma, Dawei
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/17
Coupling reaction
Heterocycle
Catalysis
Pyrrolo[2
3-d]pyrimidines
Cyclization
Design, synthesis and biological evaluation of N2,N 4-disubstituted-1,1,3-trioxo-2H,4H-pyrrolo[1,2-b][1,2,4,6] thiatriazine derivatives as HIV-1 NNRTIs
期刊论文
Bioorganic and medicinal chemistry, 2013, 卷号: 21, 期号: 22, 页码: 7091-7100
作者:
Chen,W.
;
Zhan,P.
;
DeClercq,E.
;
Pannecouque,C.
;
Balzarini,J.
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  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
Drug design
Heterocycle
HIV
NNRTIs
Pyrrolothiatriazine
Reverse transcriptase
Thienothiadiazine
Structure-based bioisosterism design, synthesis and biological evaluation of novel 1,2,4-triazin-6-ylthioacetamides as potent HIV-1 NNRTIs
期刊论文
Bioorganic and Medicinal Chemistry Letters, 2012, 卷号: 22, 期号: 23, 页码: 7155-7162
作者:
Zhan,P.
;
Li,X.
;
Li,Z.
;
Chen,X.
;
Tian,Y.
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2019/12/23
1
2
4-Triazine
Anti-HIV-1 activity
Heterocycle
HIV reverse transcriptase
NNRTIs
SAR
Structure-based bioisosterism strategy
Synthesis
Arylazolyl(azinyl)thioacetanilides. Part 10: Design, synthesis and biological evaluation of novel substituted imidazopyridinylthioacetanilides as potent HIV-1 inhibitors
期刊论文
Bioorganic and medicinal chemistry, 2012, 卷号: 20, 期号: 18, 页码: 5527-5536
作者:
Li,X.
;
Zhan,P.
;
Liu,H.
;
Li,D.
;
Wang,L.
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Anti-HIV-1 activity
Heterocycle
HIV
Imidazopyridine
NNRTIs
SAR
Scaffold hopping
Synthesis
Discovery of novel 2-(3-(2-chlorophenyl)pyrazin-2-ylthio)-N-arylacetamides as potent HIV-1 inhibitors using a structure-based bioisosterism approach
期刊论文
Bioorganic and medicinal chemistry, 2012, 卷号: 20, 期号: 23, 页码: 6795-6802
作者:
Zhan,P.
;
Chen,W.
;
Li,Z.
;
Li,X.
;
Chen,X.
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2019/12/23
Anti-HIV-1 activity
Heterocycle
HIV reverse transcriptase
NNRTIs
Pyrazinylthioacetamide
SAR
Structure-based bioisosterism strategy
Synthesis
Synthesis, crystal growth and second-order nonlinear optical properties of new pyridinium salts
期刊论文
Proceedings of SPIE - The International Society for Optical Engineering, 2012, 卷号: 8474
作者:
Tan, Jifeng
;
Li, Liang
;
Yin, Jianhong
;
Zhang, Xingfei
;
Tao, Xutang
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2019/12/23
Coulomb interactions
Crystal growth
Crystal structure
Heterocycle
Intermolecular interaction
Kurtz powder test
Non-centrosymmetric
Pyridinium salt
Second-order nonlinear optics
Single crystals
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