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科研机构
上海药物研究所 [27]
内容类型
期刊论文 [27]
发表日期
2021 [4]
2020 [2]
2019 [4]
2018 [4]
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2015 [3]
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Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Glycogen synthase kinase 3 beta inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 2, 页码: 18
作者:
Zhang, Ning
;
Tian, Yu-Nan
;
Zhou, Li-Na
;
Li, Meng-Zhu
;
Chen, Hua-Dong
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/05/24
Adaptive resistance to PI3K alpha-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 1, 页码: 13
作者:
Wang, Yu-xiang
;
Zhang, Xu
;
Ma, Qing-yang
;
Hu, Lan-dian
;
Zhang, Xi
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
期刊论文
Cell Death & Disease, 2021, 卷号: 12, 期号: 2, 页码: 1
作者:
Ning Zhang
;
Yu-Nan Tian
;
Li-Na Zhou
;
Meng-Zhu Li
;
Hua-Dong Chen
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/12/01
Activation of unfolded protein response overcomes Ibrutinib resistance in diffuse large B-cell lymphoma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 10
作者:
Zhang, Xiao-tuan
;
Hu, Xiao-bei
;
Wang, Han-lin
;
Kan, Wei-juan
;
Xu, Lei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/12/24
DLBCL
BTK inhibitor
ibrutinib resistance
UPR
TUDCA
2-DG
EZH2 inhibitors abrogate upregulation of trimethylation of H3K27 by CDK9 inhibitors and potentiate its activity against diffuse large B-cell lymphoma
期刊论文
HAEMATOLOGICA, 2020, 卷号: 105, 期号: 4, 页码: 1021-1031
作者:
Xie, Shao
;
Wei, Fan
;
Sun, Yi-ming
;
Gao, Ying-lei
;
Pan, Lu-lu
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2020/07/01
Enhancing Triple Negative Breast Cancer Immunotherapy by ICG-Templated Self-Assembly of Paclitaxel Nanoparticles
期刊论文
ADVANCED FUNCTIONAL MATERIALS, 2019, 页码: 13
作者:
Feng, Bing
;
Niu, Zifei
;
Hou, Bo
;
Zhou, Lei
;
Li, Yaping
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
immune checkpoint blockade
immunogenic cell death
immunotherapy
self-assemble
triple negative breast cancer
Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 19, 页码: 16
作者:
He, Yulong
;
Dou, Huixia
;
Gao, Dingding
;
Wang, Ting
;
Zhang, Mingming
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/07/01
Dual FABP4/5 inhibitor
Structure-based design
Lipolysis inhibition
Anti-inflammatory effects
Cell Permeable NBD Peptide-Modified Liposomes by Hyaluronic Acid Coating for the Synergistic Targeted Therapy of Metastatic Inflammatory Breast Cancer
期刊论文
MOLECULAR PHARMACEUTICS, 2019, 卷号: 16, 期号: 3, 页码: 1140-1155
作者:
Sun, Yuqing
;
Li, Xuqian
;
Zhang, Lili
;
Liu, Xiao
;
Jiang, Baohong
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
TAT-NBD peptide
curcumin
celecoxib
anti-inflammation
antimetastasis
DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2
期刊论文
CANCER MANAGEMENT AND RESEARCH, 2019, 卷号: 11, 页码: 4797-4808
作者:
Kong, Yuanyuan
;
Li, Bo
;
Chang, Shuaikang
;
Gao, Lu
;
Xu, Zhijian
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
DCZ0814
multiple myeloma
mTOR
bone marrow microenvironment
apoptosis
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