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浏览/检索结果: 共7条，第1-7条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     已选(0)清除 条数/页：5101520253035404550556065707580859095100   排序方式：请选择作者升序作者降序题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序 Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis 期刊论文 ACTA PHARMACOLOGICA SINICA, 2021, 页码: 13 作者:  Chen, Cheng;  Ren, Yong-mei;  Zhu, Jian-zhong;  Chen, Jia-li;  Feng, Zhe-ling 收藏  |  浏览/下载：56/0  |  提交时间：2022/01/04 Ainsliadimer C  interleukin-1 beta  macrophages  NLRP3 inflammasome  Sirtuin 1  adipose tissue inflammation  obesity  metabolic disorders  EX-527  dexamethasone   Discovery of 5-Benzylidene-2-phenyl-1,3-dioxane-4,6-diones as Highly Potent and Selective SIRT1 Inhibitors 期刊论文 ACS MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 12, 期号: 3, 页码: 397-403 作者:  Li, Chunpu;  Hu, Sha-Sha;  Yang, Lisheng;  Wang, Min;  Long, Jian-Dong 收藏  |  浏览/下载：57/0  |  提交时间：2021/05/24 SIRT1  inhibitor  structure-activity relationship  interaction  deacetylase   Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide +/ Sirtuin-1 pathway in mice 期刊论文 ASIAN JOURNAL OF SURGERY, 2021, 卷号: 44, 期号: 1, 页码: 213-220 作者:  Hua, Rong;  Wang, Guan-Zhen;  Shen, Qi-Wei;  Yang, Ye-Ping;  Wang, Meng 收藏  |  浏览/下载：23/0  |  提交时间：2021/05/24 NAD  NAFLD  NRK1  SIRT1  Sleeve gastrectomy   Design, Synthesis, and Biological Evaluation of 8-Mercapto-3,7-Dihydro-1H-Purine-2,6-Diones as Potent Inhibitors of SIRT1, SIRT2, SIRT3, and SIRT5 期刊论文 MOLECULES, 2020, 卷号: 25, 期号: 12, 页码: 18 作者:  Han, Haozhen;  Li, Chunpu;  Li, Man;  Yang, Lisheng;  Zhao, Sen 收藏  |  浏览/下载：36/0  |  提交时间：2020/12/24 sirtuins  inhibitor  structure-activity relationship  deacetylase   SIRT1 activator E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression 期刊论文 Atherosclerosis, 2018, 卷号: 274, 页码: 172-181 作者:  Feng, Tingting;  Liu, Peng;  Wang, Xiao;  Luo, Jinque;  Zuo, Xuan 收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 Acetylation at lysine 71 inactivates superoxide dismutase 1 and sensitizes cancer cells to genotoxic agents 期刊论文 ONCOTARGET, 2015, 卷号: 6, 期号: 24, 页码: 20578-20591 作者:  Lin, Chenchu;  Zeng, Hanlin;  Lu, Junyan;  Xie, Zuoquan;  Sun, Wenyi 收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 acetylation  camptothecin  SIRT1  superoxide dismutase  oxidative stress   Dual role of Zn2+ in maintaining structural integrity and suppressing deacetylase activity of SIRT1 期刊论文 JOURNAL OF INORGANIC BIOCHEMISTRY, 2010, 卷号: 104, 期号: 2, 页码: 180-185 作者:  Chen, Lei;  Feng, Yu;  Zhou, Yinqiu;  Zhu, Weiliang;  Shen, Xu 收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08 Zinc ion  SIRT1  Protein deacetylation  Zinc-finger motif  Noncompetitive inhibitor