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科研机构
上海药物研究所 [88]
内容类型
期刊论文 [86]
专著章节 [1]
会议论文 [1]
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2021 [3]
2020 [4]
2019 [4]
2018 [2]
2017 [6]
2016 [6]
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Nitrogenous Sesquiterpenoids from the South China Sea Nudibranch Hexabranchus sanguineus and Its Possible Sponge-Prey Acanthella cavernosa: Chiral Separation, Stereochemistry and Chemical Ecology
期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2022, 卷号: 40, 期号: 2, 页码: 235-246
作者:
Shen, Shou-Mao
;
Zhang, Zai-Yong
;
Yao, Li-Gong
;
Wang, Jian-Rong
;
Guo, Yue-Wei
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/01/18
Hexabranchus sanguineus
Acanthella cavernosa
Chiral separation
Stereochemistry
Chemical ecology
A homogeneous time-resolved fluorometric energy transfer assay for the binding assessment of FcRn with IgG antibodies
期刊论文
JOURNAL OF IMMUNOLOGICAL METHODS, 2021, 卷号: 499, 页码: 6
作者:
Song, Yakai
;
Deng, Xiaojie
;
Shi, Wei
;
Tang, Feng
;
Huang, Wei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/01/04
FcRn
TR-FRET
mAb
ADC
Pharmacokinetics
Effects of Food on the Pharmacokinetic Properties and Mass Balance of Henagliflozin in Healthy Male Volunteers
期刊论文
CLINICAL THERAPEUTICS, 2021, 卷号: 43, 期号: 9, 页码: E264-E273
作者:
Chen, Zhen-dong
;
Chen, Qian
;
Zhu, Yun-ting
;
Zhang, Yi-fan
;
Zhan, Yan
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2022/01/04
henagliflozin
food effects
mass balance
pharmacokinetics
SGLT-2 inhibitor
Uncommon Diterpenoids from the South China Sea Soft Coral Sinularia humilis and Their Stereochemistry
期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 4, 页码: 3367-3376
作者:
Sun, Li-Li
;
Li, Wang-Sheng
;
Li, Jie
;
Zhang, Hai-Yan
;
Yao, Li-Gong
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/05/24
Two new flavonoid glycosides isolated from the fruits of Catalpa ovata
期刊论文
PHARMACOGNOSY MAGAZINE, 2020, 卷号: 16, 期号: 72, 页码: 812-816
作者:
Zhang, Liu-Qiang
;
Xue, Hai-Bing
;
Zhu, Wei-Liang
;
Li, Yi-Ming
;
Chen, Kai-Xian
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2021/05/24
Antioxidant activity
Catalpa ovata
flavonoid glycosides
polyphenols
structure–
activity relationship
Safety, Clinical Activity, and Pharmacokinetics of Al flutinib (AST2818) in Patients With Advanced NSCLC With EGFR T790M Mutation
期刊论文
JOURNAL OF THORACIC ONCOLOGY, 2020, 卷号: 15, 期号: 6, 页码: 1015-1026
作者:
Shi, Yuankai
;
Zhang, Shucai
;
Hu, Xingsheng
;
Feng, Jifeng
;
Ma, Zhiyong
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  |  
浏览/下载:38/0
  |  
提交时间:2020/12/24
Alflutinib
NSCLC
EGFR T790M mutation
Efficacy
Safety
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XIV. Structurally diverse terpenoids from the twigs and needles of the endangered plant Picea brachytyla
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 169, 页码: 11
作者:
Jiang, Wei
;
Xiong, Juan
;
Zang, Yi
;
Li, Junmin
;
Osman, Ezzat E. A.
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  |  
浏览/下载:83/0
  |  
提交时间:2020/07/01
Picea brachytyla (Franch.) E.Pritz.
Pinaceae
Endangered plant
Terpenoids
Brachytylins
ATP citrate lyase (ACL)
SHP2 tyrosine phosphatase
Phytochemical and biological studies on rare and endangered plants endemic to China. Part XV. Structurally diverse diterpenoids and sesquiterpenoids from the vulnerable conifer Pseudotsuga sinensis
期刊论文
PHYTOCHEMISTRY, 2020, 卷号: 169, 页码: 14
作者:
Huang, Ting
;
Ying, Sheng-Hui
;
Li, Jing-Ya
;
Chen, Hao-Wei
;
Zang, Yi
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2020/07/01
Pseudotsuga sinensis dode
Pinaceae
Rare and endangered plants (REPs)
Degraded diterpenoids
Pseudosinins
ATP-Citrate lyase (ACL)
Identifying the active components of Baihe-Zhimu decoction that ameliorate depressive disease by an effective integrated strategy: a systemic pharmacokinetics study combined with classical depression model tests
期刊论文
CHINESE MEDICINE, 2019, 卷号: 14, 期号: 1, 页码: 11
作者:
Zhong, Ming
;
Tian, Xiaoting
;
Chen, Shuoji
;
Chen, Mingcang
;
Guo, Ziqiong
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Baihe-Zhimu decoction
Antidepressant
Timosaponin BII
Timosaponin BIII
Drug discovery
Preclinical evaluation of 3D185, a novel potent inhibitor of FGFR1/2/3 and CSF-1R, in FGFR-dependent and macrophage-dominant cancer models
期刊论文
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2019, 卷号: 38, 期号: 1, 页码: 16
作者:
Peng, Xia
;
Hou, Pengcong
;
Chen, Yi
;
Dai, Yang
;
Ji, Yinchun
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2020/07/01
Kinase inhibitor
FGFR
CSF-1R
Tumor microenvironment
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