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科研机构
上海药物研究所 [124]
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期刊论文 [123]
项目 [1]
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2021 [12]
2020 [11]
2019 [6]
2018 [8]
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2016 [11]
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Define Mesenchymal Stem Cell from Its Fate: Biodisposition of Human Mesenchymal Stem Cells in Normal and Concanavalin A-Induced Liver Injury Mice
期刊论文
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2021, 卷号: 379, 期号: 2, 页码: 125-133
作者:
Han, Li
;
Ma, Chenhui
;
Peng, Huige
;
Wu, Zhitao
;
Xu, Huiming
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/01/04
Dynamics of Post-Translational Modification Inspires Drug Design in the Kinase Family
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 20, 页码: 15111-15125
作者:
Zhang, Huimin
;
He, Jixiao
;
Hu, Guang
;
Zhu, Fei
;
Jiang, Hao
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/01/04
Pharmacodynamic, pharmacokinetic, and phase 1a study of bisthianostat, a novel histone deacetylase inhibitor, for the treatment of relapsed or refractory multiple myeloma
期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 9
作者:
Zhou, Yu-bo
;
Zhang, Yang-ming
;
Huang, Hong-hui
;
Shen, Li-jing
;
Han, Xiao-feng
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2021/11/04
multiple myeloma
HDAC inhibitor
bisthianostat
pharmacodynamics
pharmacokinetics
phase 1a clinical trial
antitumor drug
PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation
期刊论文
CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10
作者:
Yang, Jun
;
Wang, Juan
;
Liu, Yuan
;
Zhang, Yu
;
Huang, Wenjing
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2021/08/17
Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury
期刊论文
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557
作者:
He, Yisheng
;
Zhang, Wei
;
Ma, Jiang
;
Xia, Qingsu
;
Song, Zijing
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2021/08/17
Targeting sorting nexin 10 improves mouse colitis via inhibiting PIKfyve-mediated TBK1/c-Rel signaling activation
期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 169, 页码: 11
作者:
Bao, Weilian
;
Liu, Xiaohong
;
You, Yan
;
Hou, Hui
;
Wang, Xu
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2021/11/16
SNX10
IBD
Macrophage
PIKfyve
TBK1
PPI inhibitor
MiR-337-3p lowers serum LDL-C level through targeting PCSK9 in hyperlipidemic mice
期刊论文
METABOLISM-CLINICAL AND EXPERIMENTAL, 2021, 卷号: 119, 页码: 12
作者:
Xu, Xiaoding
;
Dong, Yunxia
;
Ma, Ningning
;
Kong, Weiwen
;
Yu, Chuwei
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/08/17
miR-337-3p
PCSK9
LDL-C
Hyperlipidemia
Dual regulation
Chemical profiling of Huashi Baidu prescription, an effective anti-COVID-19 TCM formula, by UPLC-Q-TOF/MS
期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2021, 卷号: 19, 期号: 6, 页码: 473-480
作者:
Wei Wen-Long
;
Wu Shi-Fei
;
Li Hao-Jv
;
Li Zhen-Wei
;
Qu Hua
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/08/17
Huashi Baidu prescription
Corona virus disease 2019
Characterization of chemical constituents
ELISA
Third-generation EGFR inhibitor HS-10296 in combination with famitinib, a multi-targeted tyrosine kinase inhibitor, exerts synergistic antitumor effects through enhanced inhibition of downstream signaling in EGFR-mutant non-small cell lung cancer cells
期刊论文
THORACIC CANCER, 2021, 页码: 9
作者:
Zhang, Mi
;
Quan, Haitian
;
Fu, Li
;
Li, Yun
;
Fu, Haoyu
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/05/24
EGFR‐
mutant non‐
small cell lung cancer
famitinib
HS‐
10296
multi‐
targeted tyrosine kinase inhibitor
third‐
generation EGFR inhibitor
Kinetics-Driven Drug Design Strategy for Next-Generation Acetylcholinesterase Inhibitors to Clinical Candidate
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 4, 页码: 1844-1855
作者:
Zhou, Yu
;
Fu, Yan
;
Yin, Wanchao
;
Li, Jian
;
Wang, Wei
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2021/05/24
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