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Design, synthesis, and structure-activity relationships of novel 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinoline and 5,8,12,12a-tetrahydro-6H-thieno[2 ',3 ': 4,5]pyrido[2,1-a]isoquinoline derivatives as cellular activators of adenosine 5 '-monophosphate-activated protein kinase (AMPK) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 8, 页码: 2017-2027
作者:  Gu, Zhanni;  Wu, Lingyan;  Duan, Yanan;  Wang, Jiang;  Zhou, Shengbin
收藏  |  浏览/下载:39/0  |  提交时间:2019/01/08
Design, synthesis and. biological evaluation of 4,7,12,12a-tetrahydro-5H-thieno[3 ',2 ':3,4]pyrido[1,2-b]isoquinolines as novel adenosine 5 '-monophosphate-activated protein kinase (AMPK) indirect activators for the treatment of type 2 diabetes 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 448-464
作者:  Zhou, Shengbin;  Duan, Yanan;  Wang, Jiang;  Zhang, Jin;  Sun, Haifeng
收藏  |  浏览/下载:34/0  |  提交时间:2019/01/08
Tetrahydroberberine blocks ATP-sensitive potassium channels in dopamine neurons acutely-dissociated from rat substantia nigra pars compacta 期刊论文
NEUROPHARMACOLOGY, 2010, 卷号: 59, 期号: 7-8, 页码: 567-572
作者:  Wu, Chen;  Yang, Kechun;  Liu, Qiang;  Wakui, Matoko;  Jin, Guo-Zhang
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
NMR Characterization and Structural Elucidation of Fluorine Derivative of Tetrahydroberberine 期刊论文
Chinese Journal of Magnetic Resonance, 2009, 卷号: 26, 期号: 1, 页码: 111-119
作者:  ZHANG Pei-xuan;  LI Jian-feng;  WEI Ya-bing;  SHEN Jing-shan
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Tetrahydroberberine blocks membrane K+ channels underlying its inhibition of intracellular message-mediated outward currents in acutely dissociated CA1 neurons from rat hippocampus 期刊论文
BRAIN RESEARCH, 1997, 卷号: 775, 期号: 1-2, 页码: 214-218
作者:  Wu, J;  Jin, GZ
收藏  |  浏览/下载:15/0  |  提交时间:2019/01/08
Tetrahydroberberine inhibits acetylcholine-induced K+ current in acutely dissociated rat hippocampal CA1 pyramidal neurons 期刊论文
NEUROSCIENCE LETTERS, 1997, 卷号: 222, 期号: 2, 页码: 115-118
作者:  Wu, J;  Jin, GZ
收藏  |  浏览/下载:14/0  |  提交时间:2019/01/08
Tetrahydroprotoberberine analogs antagonize alpha(1)-adrenoceptors and inhibit mobilization of intracellular calcium 期刊论文
DRUG DEVELOPMENT RESEARCH, 1996, 卷号: 39, 期号: 2, 页码: 191-196
作者:  Han, CD;  Lu, ZZ;  Wei, X;  Jin, GZ
收藏  |  浏览/下载:8/0  |  提交时间:2019/01/08
Tetrahydroberberine suppresses dopamine-induced potassium current in acutely dissociated CA1 pyramidal neurons from rat hippocampus 期刊论文
NEUROSCIENCE LETTERS, 1996, 卷号: 207, 期号: 3, 页码: 155-158
作者:  Wu, J;  Jin, GZ
收藏  |  浏览/下载:10/0  |  提交时间:2019/01/08
On the central inhibition action of tetrahydroberberine without relevance to GABA receptors 会议论文
作者:  Wang, X L;  Jin, G Z;  Zhou, T C
收藏  |  浏览/下载:11/0  |  提交时间:2019/01/08


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