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科研机构
上海药物研究所 [56]
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期刊论文 [55]
学位论文 [1]
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2020 [2]
2018 [5]
2017 [4]
2016 [5]
2015 [7]
2014 [1]
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Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network -molecular docking-LC-MSE analysis
期刊论文
JOURNAL OF INTEGRATIVE MEDICINE-JIM, 2020, 卷号: 18, 期号: 3, 页码: 229-241
作者:
Zhang, Zi-jia
;
Wu, Wen-yong
;
Hou, Jin-jun
;
Zhang, Lin-lin
;
Li, Fei-fei
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2020/07/01
Lung-toxin Dispelling Formula No. 1
COVID-19
3C-like protease
Network pharmacology
Molecular docking
Meridian tropism
Discovery of a Potent and Selective NF-kappa B-Inducing Kinase (NIK) Inhibitor That Has Anti-inflammatory Effects in Vitro and in Vivo
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 63, 期号: 8, 页码: 4388-4407
作者:
Li, Zhiqiang
;
Li, Xinzhi
;
Su, Ming-Bo
;
Gao, Li-Xin
;
Zhou, Yu-Bo
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2020/07/01
Traceable Bioinspired Nanoparticle for the Treatment of Metastatic Breast Cancer via NIR-Trigged Intracellular Delivery of Methylene Blue and Cisplatin
期刊论文
ADVANCED MATERIALS, 2018, 卷号: 30, 期号: 34
作者:
Zhai, Yihui
;
Ran, Wei
;
Su, Jinghan
;
Lang, Tianqun
;
Meng, Jia
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/01/08
bioinspired nanoparticles
cytotoxic T lymphocytes
metastasis
triple-negative breast cancer
tumor penetration
Sensitive detection of Bacillus thuringiensis Cry1B toxin based on camel single-domain antibodies
期刊论文
MICROBIOLOGYOPEN, 2018, 卷号: 7, 期号: 4
作者:
Zhong, Wenjing
;
Li, Guanghui
;
Yu, Xiaolu
;
Zhu, Min
;
Gong, Likun
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
biotin-streptavidin system
Cry1B
nanobody
phage display
sandwich ELISA
Solution structure of extracellular loop of human beta 4 subunit of BK channel and its biological implication on ChTX sensitivity
期刊论文
SCIENTIFIC REPORTS, 2018, 卷号: 8
作者:
Wang, Yanting
;
Lan, Wenxian
;
Yan, Zhenzhen
;
Gao, Jing
;
Liu, Xinlian
收藏
  |  
浏览/下载:74/0
  |  
提交时间:2019/01/08
Improved Protein Toxin Delivery Based on ATTEMPTS Systems
期刊论文
CURRENT DRUG TARGETS, 2018, 卷号: 19, 期号: 4, 页码: 380-392
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Min, Kyoung Ah
;
Wang, Huiyuan
;
Shin, Meong Cheol
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2019/01/08
Protein toxin
ribosome-inactivating protein
immunotoxin
cell-penetrating peptide (CPP)
gelonin
tumor-targeting delivery
The involvement of multidrug and toxin extrusion protein 1 in the distribution and excretion of berberine
期刊论文
XENOBIOTICA, 2018, 卷号: 48, 期号: 3, 页码: 314-323
作者:
Xiao, Ling
;
Xue, Yaru
;
Zhang, Cuifeng
;
Wang, Le
;
Lin, Yunfei
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  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Berberine
MATE1
hepatobiliary distribution
excretion
DDIs
Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance
期刊论文
MOLECULAR PHARMACEUTICS, 2017, 卷号: 14, 期号: 5, 页码: 1429-1438
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Jin, Hongyue
;
Tang, Yisi
;
Wu, Aihua
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2019/01/08
multidrug resistance
trichosanthin
matrix metalloproteinase
paclitaxel
caspase 9 phosphorylation
intein-mediated protein ligation
PEGylation
A small-molecule inhibitor of NF-kappa B-inducing kinase (NIK) protects liver from toxin-induced inflammation, oxidative stress, and injury
期刊论文
FASEB JOURNAL, 2017, 卷号: 31, 期号: 2, 页码: 711-718
作者:
Ren, Xiaomeng
;
Li, Xinzhi
;
Jia, Linna
;
Chen, Deheng
;
Hou, Hai
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
NIK
liver injury
inflammation
CCl4
Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature
期刊论文
BIOMATERIALS, 2017, 卷号: 116, 页码: 57-68
作者:
Chen, Yingzhi
;
Zhang, Meng
;
Jin, Hongyue
;
Tang, Yisi
;
Wang, Huiyuan
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
Intein-mediated protein ligation (IPL)
Protein toxin
Trichosanthin
Site-specific PEGylation
Gelatinase
Cell-penetrating peptide
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