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Cytochrome P450-Mediated Metabolism and CYP Inhibition for the Synthetic Peroxide Antimalarial OZ439 期刊论文
ACS INFECTIOUS DISEASES, 2021, 卷号: 7, 期号: 7, 页码: 1885-1893
作者:  Shackleford, David M.;  Chiu, Francis C. K.;  Katneni, Kasiram;  Blundell, Scott;  McLaren, Jenna
收藏  |  浏览/下载:59/0  |  提交时间:2021/11/04
Furmonertinib (Alflutinib, AST2818) is a potential positive control drug comparable to rifampin for evaluation of CYP3A4 induction in sandwich-cultured primary human hepatocytes 期刊论文
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 10
作者:  Wu, Ya-li;  Xue, Ya-ru;  Guo, Zi-tao;  Chen, Zhen-dong;  Ge, Xin-yu
收藏  |  浏览/下载:22/0  |  提交时间:2021/08/17
Functional Proliferating Human Hepatocytes: In Vitro Hepatocyte Model for Drug Metabolism, Excretion, and Toxicity 期刊论文
DRUG METABOLISM AND DISPOSITION, 2021, 卷号: 49, 期号: 4, 页码: 305-313
作者:  Qiao, Shida;  Feng, Sisi;  Wu, Zhitao;  He, Ting;  Ma, Chen
收藏  |  浏览/下载:27/0  |  提交时间:2021/05/24
Pharmacokinetic Drug-drug Interaction of Antibiotics Used in Sepsis Care in China 期刊论文
CURRENT DRUG METABOLISM, 2021, 卷号: 22, 期号: 1, 页码: 5-23
作者:  Yu, Xuan;  Chu, Zixuan;  Li, Jian;  He, Rongrong;  Wang, Yaya
收藏  |  浏览/下载:69/0  |  提交时间:2021/05/24
Alflutinib (AST2818), primarily metabolized by CYP3A4, is a potent CYP3A4 inducer 期刊论文
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:  Liu, Xiao-yun;  Guo, Zi-tao;  Chen, Zhen-dong;  Zhang, Yi-fan;  Zhou, Jia-lan
收藏  |  浏览/下载:76/0  |  提交时间:2020/07/01
The Nonclinical Pharmacokinetics and Prediction of Human Pharmacokinetics of SPH3127, a Novel Direct Renin Inhibitor 期刊论文
EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2020, 卷号: 45, 期号: 1, 页码: 15-26
作者:  Zhang, Leduo;  Mao, Yu;  Gao, Zhiwei;  Chen, Xiaoyan;  Li, Xin
收藏  |  浏览/下载:46/0  |  提交时间:2020/07/01
Intravenous formulation of Panax notoginseng root extract: human pharmacokinetics of ginsenosides and potential for perpetrating drug interactions 期刊论文
ACTA PHARMACOLOGICA SINICA, 2019, 卷号: 40, 期号: 10, 页码: 1351-1363
作者:  Pintusophon, Salisa;  Niu, Wei;  Duan, Xiao-na;  Olaleye, Olajide E.;  Huang, Yu-hong
收藏  |  浏览/下载:32/0  |  提交时间:2020/07/01
Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids 期刊论文
ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209
作者:  Yang, Mengbi;  Ma, Jiang;  Ruan, Jianqing;  Ye, Yang;  Fu, Peter Pi-Cheng
收藏  |  浏览/下载:9/0  |  提交时间:2020/07/01
Induction of Cytochrome P450 Involved in the Accelerated Blood Clearance Phenomenon Induced by PEGylated Liposomes In Vivo 期刊论文
DRUG METABOLISM AND DISPOSITION, 2019, 卷号: 47, 期号: 4, 页码: 364-376
作者:  Wang, Fengling;  Wu, Yifan;  Zhang, Jiwen;  Wang, Huihui;  Xie, Xiaoting
收藏  |  浏览/下载:2/0  |  提交时间:2020/07/01
An Adaption of Human-Induced Hepatocytes to In Vitro Genetic Toxicity Tests 期刊论文
Mutagenesis, 2018
作者:  Liu, Weiying;  Xi, Jing;  Cao, Yiyi;  You, Xinyue;  Chen, Ruixue
收藏  |  浏览/下载:97/0  |  提交时间:2019/01/08


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